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Deep and superficial vibrissal nerves innervate nearly exclusive targets in the large follicle\u2013sinus complexes (F\u2010SCs) at the base of each tactile vibrissa. Dermal plexus nerves innervate the fur between the vibrissae. Each type of nerve provides a similar variety of sensory endings, albeit to different targets. In this study, Winkelmann and Sevier\u2010Munger reduced silver techniques revealed that most of the endings differntiate postnatally in an overlapping sequence like that observed previously in the rat. Afferents from the deep vibrissal nerves begin to differentiate first, followed successively by those from superficial vibrissal nerves and the dermal plexus. Within each type of nerve, Merkel endings begin to differentiate first, followed successively by lanceolate endings and circumferential endings. In the ferret, the differentiation of the intervibrissal fur and its innervation is slightly delayed but substantially overlaps the development of the vibrissal innervation, whereas in the rat it occurs almost entirely later. There was no evidence of a transient exuberant or misplaced innervation or other secondary remodeling. Differentiating afferents and endings are located only in the sites normally seen in the adult, suggesting a high degree of afferent\u2010target specificity. In the ferret, innervation is virtually lacking in one target\u2014the inner conical body of the F\u2010SCs, which is densely innervated in the rat. This lack was due to a failure of innervation to develop rather than to a secondary elimination of a transient innervation. \u00a9 1993 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/cne.903330302","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T08:54:09Z","timestamp":1104569649000},"page":"309-325","source":"Crossref","is-referenced-by-count":13,"title":["Sequential differentiation of sensory innervation in the mystacial pad of the ferret"],"prefix":"10.1002","volume":"333","author":[{"given":"T. M.","family":"Mosconi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. 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