{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T19:48:46Z","timestamp":1762112926686},"reference-count":47,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2004,10,9]],"date-time":"2004-10-09T00:00:00Z","timestamp":1097280000000},"content-version":"vor","delay-in-days":3974,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Comparative Neurology"],"published-print":{"date-parts":[[1993,11,22]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The brain of the sturgeon has recently been shown to contain at least two forms of GnRH (gonadotropin\u2010releasing hormone), mammalian GnRH (mGnRH) and chicken GnRH\u2010II (cGnRH\u2010II). In this study, we compared the distribution of immunoreactive (ir) mGnRH and cGnRH\u2010II in the brain of immature Siberian sturgeons (<jats:italic>Acipenser baeri<\/jats:italic>). The overall distribution of mGnRH was very similar to the distribution of sGnRH in teleosts such as salmonids or cyprinids. mGnRH\u2010ir perikarya were observed in the olfactory nerves and bulbs, the telencephalon, the preoptic region, and the mediobasal hypothalamus. All these cell bodies are located along a continuum of ir\u2010fibers that could be traced from the olfactory nerve to the nerve to the hypothalamopituitary interface. No ir\u2010fibers were observed in the anterior lobe of the pituitary, but a few were seen to enter the neurointermediate lobe. mGnRH\u2010ir fibers were detected in many parts of the brain, particularly in the forebrain. mGnRH\u2010ir cerebrospinal fluid\u2010containing cells were observed in the telencephalon, the preoptic region, and the mediobasal hypothalamus. In contrast, cGnRH\u2010II was present mainly in the posterior brain, although a few ir axons were seen in the above\u2010mentioned territories. In particular, cGnRH\u2010II\u2010ir cell bodies, negative for mGnRH, were consistently observed in the nucleus of the medial longitudinal fasciculus of the midbrain tegmentum. The cGnRH\u2010II innervation in the optic tectum, cerebellum, vagal lobe, and medulla oblongata was more abundant than the mGnRH innervation in the same areas. This study provides evidence that the organization of the GnRH systems in a primitive bony fish is, highly similar to that reported in teleosts and further documents the differential distribution of two forms of GnRH in the brain of vertebrates. \u00a9 1993 Wiley\u2010Liss,Inc.<\/jats:p>","DOI":"10.1002\/cne.903370404","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T09:09:07Z","timestamp":1104570547000},"page":"568-583","source":"Crossref","is-referenced-by-count":62,"title":["Comparative distribution of mammalian GnRH (gonadotrophin\u2010releasing hormone) and chicken GnRH\u2010II in the brain of the immature siberian sturgeon (<i>Acipenser baeri<\/i>)"],"prefix":"10.1002","volume":"337","author":[{"given":"Emmanuel","family":"Lepr\u00eatre","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Anglade","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Williot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frans","family":"Vandesande","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00e9rard","family":"Tramu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivier","family":"Kah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,9]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"386","article-title":"The olfactory bulb and related nuclei of the sturgeon (Scaphirhynchus platorynchus). 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