{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T13:19:35Z","timestamp":1770297575498,"version":"3.49.0"},"reference-count":53,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2004,10,10]],"date-time":"2004-10-10T00:00:00Z","timestamp":1097366400000},"content-version":"vor","delay-in-days":3478,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Comparative Neurology"],"published-print":{"date-parts":[[1995,4,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The rhythmically active pyloric and gastric mill motor patterns in the stomatogastric ganglion of the crab, <jats:italic>Cancer borealis<\/jats:italic>, are influenced by modulatory projection neurons whose somata are located primarily in the other ganglia of the stomatogastric nervous system. One of these projection neurons exhibits substance P\u2010like immunolabeling. However, bath application of substance P does not influence these motor patterns. To determine whether a different peptide is responsible for the substance P\u2010like immunolabeling, we studied the presence and physiological effects of the locustatachykinins and the leucokinins, two families of tachykininlike peptides originally identified in insect nervous systems. Locustatachykinin\u2010hke immunolabeling has the same distribution in the stomatogastric nervous system as substance P\u2010like immunolabeling and colocalizes with it in the majority of immunopositive structures. Preincubation of locustatachykinin antibody with substance P, and preincubation of substance P antibody with locustatachykinin, blocks subsequent immunolabeling in the stomatogastric nervous system. In contrast, we found no leucokinin\u2010like immunolabeling in this system. Bath application to the stomatogastric ganglion of individual locustatachykinins or leucokinins excited the pyloric rhythm in a state\u2010dependent manner. Each peptide family had distinct effects on the pyloric rhythm. Thus, both of these tachykinin\u2010like peptide families are likely related to native neuropeptides that influence the pyloric rhythm. Furthermore, a member of the locustatachykinin family is likely to be the source of the previously identified substance P\u2010like immunoreactivity in the stomatogastric nervous system. \u00a9 1995 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/cne.903540209","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T22:19:23Z","timestamp":1104617963000},"page":"282-294","source":"Crossref","is-referenced-by-count":67,"title":["Distribution and effects of tachykinin\u2010like peptides in the stomatogastric nervous system of the crab, <i>Cancer borealis<\/i>"],"prefix":"10.1002","volume":"354","author":[{"given":"Dawn M.","family":"Blitz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew E.","family":"Christie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eve","family":"Marder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael P.","family":"Nusbaum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,10]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"2320","article-title":"Neural control of limb coordination. 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