{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T13:56:43Z","timestamp":1791035803766,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2012,5,17]],"date-time":"2012-05-17T00:00:00Z","timestamp":1337212800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Numer Methods Biomed Eng"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Computational head and brain volume conductor modeling is a practical and non\u2010invasive method to investigate neuroelectrical activity in the brain. Anatomical structures included in a model affect the flow of volume currents and the resulting scalp surface potentials. The influence of different tissues within the head on scalp surface potentials was investigated by constructing five highly detailed, realistic head models from segmented and processed Visible Human Man digital images. The models were: (1) model with 20 different tissues, that is, skin, dense connective tissue (fat), aponeurosis (muscle), outer, middle and inner tables of the scalp, dura matter, arachnoid layer (including cerebrospinal fluid), pia matter, six cortical layers, eye tissue, muscle around the eye, optic nerve, temporal muscle, white matter and internal air, (2) model with three main inhomogeneities, that is, scalp, skull, brain, (3) model with homogeneous scalp and remaining inhomogeneities, (4) model with homogeneous skull and remaining inhomogeneities, and (5) model with homogeneous brain matter and remaining inhomogeneities. Scalp potentials because of three different dipolar sources in the parietal\u2010occipital lobe were computed for all five models. Results of a forward solution revealed that tissues included in the model and the dipole source location directly affect the simulated scalp surface potentials. The major finding indicates that significant change in the scalp surface potentials is observed when the brain's distinctions are removed. The other modifications, for example, layers of the scalp and skull are important too, but they have less effect on the overall results. Copyright \u00a9\u20092012 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/cnm.2483","type":"journal-article","created":{"date-parts":[[2012,5,17]],"date-time":"2012-05-17T17:53:15Z","timestamp":1337277195000},"page":"1144-1155","source":"Crossref","is-referenced-by-count":6,"title":["Computational representation of a realistic head and brain volume conductor model: electroencephalography simulation and visualization study"],"prefix":"10.1002","volume":"28","author":[{"given":"Asta","family":"Kybartaite","sequence":"first","affiliation":[{"name":"Institute of Neurosciences Lithuanian University of Health Sciences  Kaunas Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,5,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01132768"},{"key":"e_1_2_7_3_1","volume-title":"Electroencephalography: Basic Principles, Clinical Applications and Related Fields","author":"Neidermeyer E","year":"2005"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004691-200201000-00001"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1350-4533(99)00038-7"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2005.10.014"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1023\/B:BRAT.0000032859.68959.76"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.10152"},{"key":"e_1_2_7_9_1","first-page":"217","article-title":"Pre\u2010operative planning and intra\u2010operative guidance in modern neurosurgery: a review of 300 cases","volume":"81","author":"Wadley J","year":"1999","journal-title":"Annals of the Royal College of Surgeons of England"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/32\/1\/014"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1109\/10.887939"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10548-005-6029-x"},{"key":"e_1_2_7_13_1","first-page":"406","article-title":"A comparison of different numerical methods for solving the forward problem in EEG and MEG","volume":"34","author":"Pruis GW","year":"1993","journal-title":"Physiological Measurement"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-2607(98)00084-4"},{"key":"e_1_2_7_15_1","unstructured":"Finite Element Method. Available at:http:\/\/www.finite\u2010element\u2010method.info> accessed 12.09.2011."},{"key":"e_1_2_7_16_1","unstructured":"LaarneP.2000.Implementation of a Realistic Conductivity Model for the Head.PhD Thesis Tampere University of Technology Tampere. 47 p."},{"key":"e_1_2_7_17_1","unstructured":"Boundary Element Method. Available at:http:\/\/www.boundary\u2010element\u2010method.com> accessed 12.09.2011."},{"issue":"2","key":"e_1_2_7_18_1","first-page":"14","article-title":"The visible human project","volume":"18","author":"Ackerman M","year":"1991","journal-title":"The Journal of Biocommunication"},{"key":"e_1_2_7_19_1","unstructured":"National Institutes of Health.Visible Human Project U.S. National Library of Medicine (NLM). Available from:http:\/\/www.nlm.nih.gov\/research\/visible\/visible_human.html> accessed 12.09.2011."},{"key":"e_1_2_7_20_1","unstructured":"NarraGN.2006.3D Segmentation of Medical Volumes Using Level Sets.MSc Thesis Tampere University of Technology Tampere.65p."},{"key":"e_1_2_7_21_1","volume-title":"The Human Nervous System","author":"Paxinos G","year":"2003"},{"key":"e_1_2_7_22_1","unstructured":"TokanoN.2002.Reduction of ECG Leads and Equivalent Sources Using Orthogonalization and Clustering Techniques.PhD Dissertation publication 382 Tampere University of Technology Tampere Finland."},{"key":"e_1_2_7_23_1","unstructured":"Ryyn\u00e4nenO.2002.Model\u2010Based Inverse Solution of Cortical EEG Potentials.MSc Thesis Tampere University of Technology Tampere.111p."},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/acprof:oso\/9780195058239.001.0001"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1014590923185"},{"key":"e_1_2_7_26_1","first-page":"910","article-title":"The conductivity of brain tissues: comparison of results in vivo and in vitro measurements","volume":"1","author":"Latikka JA","year":"2001","journal-title":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Istanbul, Turkey"},{"key":"e_1_2_7_27_1","first-page":"1426","volume-title":"Fundamental of Neuroscience","author":"Squire LR","year":"2003"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1109\/10.995679"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1515\/bmte.2000.45.7-8.211"},{"key":"e_1_2_7_30_1","unstructured":"ArolaT.2003.Lead Field Based Simulation Tool for Dipolar Bioelectric Fields.MSc Thesis Tampere University of Technology Tampere. 76 p."},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1109\/10.40805"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0013-4694(97)00147-8"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.60.7.1062"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1109\/10.605429"}],"container-title":["International Journal for Numerical Methods in Biomedical Engineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcnm.2483","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cnm.2483","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T15:57:25Z","timestamp":1697471845000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cnm.2483"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5,17]]},"references-count":33,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["10.1002\/cnm.2483"],"URL":"https:\/\/doi.org\/10.1002\/cnm.2483","archive":["Portico"],"relation":{},"ISSN":["2040-7939","2040-7947"],"issn-type":[{"value":"2040-7939","type":"print"},{"value":"2040-7947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,5,17]]}}}