{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T16:21:04Z","timestamp":1759940464036,"version":"3.41.2"},"reference-count":49,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2017,4,11]],"date-time":"2017-04-11T00:00:00Z","timestamp":1491868800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Bizkaia Talent and European Commission","award":["AYD-000-285"],"award-info":[{"award-number":["AYD-000-285"]}]},{"name":"Spanish Ministry of Economics and Competitiveness (MINECO)","award":["SEV-2013-0323"],"award-info":[{"award-number":["SEV-2013-0323"]}]},{"name":"Plan Estatal de Investigaci\u00f3n, Desarrollo e Innovaci\u00f3n Orientada a los Retos de la Sociedad","award":["MTM2015-69992-R"],"award-info":[{"award-number":["MTM2015-69992-R"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Numer Methods Biomed Eng"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cortical spreading depression, a depolarization wave originating in the visual cortex and traveling towards the frontal lobe, is commonly accepted as a correlate of migraine visual aura. As of today, little is known about the mechanisms that can trigger or stop such phenomenon. However, the complex and highly individual characteristics of the brain cortex suggest that the geometry might have a significant impact in supporting or contrasting the propagation of cortical spreading depression. Accurate patient\u2010specific computational models are fundamental to cope with the high variability in cortical geometries among individuals, but also with the conduction anisotropy induced in a given cortex by the complex neuronal organisation in the grey matter. In this paper, we integrate a distributed model for extracellular potassium concentration with patient\u2010specific diffusivity tensors derived locally from diffusion tensor imaging data.<\/jats:p>","DOI":"10.1002\/cnm.2874","type":"journal-article","created":{"date-parts":[[2017,2,22]],"date-time":"2017-02-22T22:06:40Z","timestamp":1487801200000},"source":"Crossref","is-referenced-by-count":10,"title":["Patient\u2010specific computational modeling of cortical spreading depression via diffusion tensor imaging"],"prefix":"10.1002","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7067-5623","authenticated-orcid":false,"given":"Julia M.","family":"Kroos","sequence":"first","affiliation":[{"name":"Basque Center for Applied Mathematics  Bilbao Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabella","family":"Marinelli","sequence":"additional","affiliation":[{"name":"Basque Center for Applied Mathematics  Bilbao Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibai","family":"Diez","sequence":"additional","affiliation":[{"name":"Comp. Neuroimaging Lab, BioCruces Health Research Institute Cruces University Hospital  Barakaldo Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jesus M.","family":"Cortes","sequence":"additional","affiliation":[{"name":"Comp. Neuroimaging Lab, BioCruces Health Research Institute Cruces University Hospital  Barakaldo Spain"},{"name":"Ikerbasque: The Basque Foundation for Science  Bilbao Spain"},{"name":"Department of Cell Biology and Histology University of the Basque Country (UPV\/EHU)  Leioa Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastiano","family":"Stramaglia","sequence":"additional","affiliation":[{"name":"Basque Center for Applied Mathematics  Bilbao Spain"},{"name":"Dipartimento di Fisica Universita di Bari  Italy"},{"name":"INFN  Sezione di Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Gerardo\u2010Giorda","sequence":"additional","affiliation":[{"name":"Basque Center for Applied Mathematics  Bilbao Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,4,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00482-008-0653-9"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2014.14"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-86210-6"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.2001.81.3.1065"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.4821955"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3770"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1515\/revneuro-2014-0069"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(78)85447-2"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0010-4825(95)00051-8"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.physd.2015.06.008"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/2190-8567-3-7"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbiomolbio.2011.06.014"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euu257"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbiomolbio.2014.08.009"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.media.2011.07.003"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.4926428"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2008.12.003"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/cnm.1443"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncom.2015.00029"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2007.01.004"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncom.2016.00006"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1999.tb07965.x"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.171473898"},{"key":"e_1_2_8_25_1","first-page":"1","article-title":"Magnetic resonance imaging of mean values and anisotropy of electrical conductivity in the human brain","volume":"55","author":"Sekino M","year":"2004","journal-title":"Neurol Clin Neurophysiol"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1109\/TBME.2008.923159"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10827-011-0358-4"},{"volume-title":"Dynamical Systems in Neuroscience: The Geometry of Excitability and Bursting (Computational Neuroscience)","year":"2007","author":"Izhikevich EM","key":"e_1_2_8_28_1"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10827-008-0132-4"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1109\/10.310090"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(61)86902-6"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1076\/noph.28.2.101.23739"},{"key":"e_1_2_8_33_1","first-page":"49","article-title":"Evolution equations semigroups and functional analysis: degenerate evolution systems modeling the cardiac electric field at micro and macroscopic level","volume":"50","author":"Colli Franzone P","year":"2002","journal-title":"Prog Nonlin"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2012.01.021"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep10532"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-540-85268-1"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1209\/0295-5075\/111\/68007"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2015.01024"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.20279"},{"issue":"3","key":"e_1_2_8_40_1","first-page":"458","article-title":"High b\u2010value diffusion (b=3000\u2009s\/mm2) MR imaging in cerebral gliomas at 3T: visual and quantitative comparisons with b=1000\u2009s\/mm2","volume":"29","author":"Seo HS","year":"2008","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2013.00031"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.1076"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/cmr.a.20049"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-88-470-1935-5_12"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1109\/TBME.2011.2160347"},{"volume-title":"Brodmann's Localisation in the Cerebral Cortex \u2010 The Principles of Comparative Localisation in the Cerebral Cortex Based on Cytoarchitectonics","year":"2006","author":"Brodmann K","key":"e_1_2_8_46_1"},{"volume-title":"Theory and Practice of Finite Elements","year":"2013","author":"Ern A","key":"e_1_2_8_47_1"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1137\/1.9780898718003"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004647-199904000-00004"},{"journal-title":"A computational multiscale model of cortical spreading depression propagation","year":"2017","author":"Gerardo\u2010Giorda L","key":"e_1_2_8_50_1"}],"container-title":["International Journal for Numerical Methods in Biomedical Engineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcnm.2874","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cnm.2874","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T17:06:06Z","timestamp":1693674366000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cnm.2874"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,11]]},"references-count":49,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1002\/cnm.2874"],"URL":"https:\/\/doi.org\/10.1002\/cnm.2874","archive":["Portico"],"relation":{},"ISSN":["2040-7939","2040-7947"],"issn-type":[{"type":"print","value":"2040-7939"},{"type":"electronic","value":"2040-7947"}],"subject":[],"published":{"date-parts":[[2017,4,11]]},"article-number":"e2874"}}