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The results are in good agreement with the available measurement data for both inspiration and expiration. A detailed sensitivity analysis of the dissipation and viscous resistance in a branch then examines the ratio of the viscous resistance to that for a fully developed Poiseuille flow, <jats:italic>Z<\/jats:italic>. As other researchers have noted, the calculated resistances give lower values than those from the standard correlation of Pedley et al. The results demonstrate that the resistance is sensitive to the velocity profile upstream of the bifurcations and explain from fluid dynamical considerations the apparent sensitivity of the resistance to the generation number of the branch. The paper also suggests a revised value for the calibration constant in the expression for <jats:italic>Z<\/jats:italic>. Finally, a limited set of results are presented for junction losses, and for expiration.<\/jats:p>","DOI":"10.1002\/cnm.2898","type":"journal-article","created":{"date-parts":[[2017,5,19]],"date-time":"2017-05-19T00:46:39Z","timestamp":1495154799000},"source":"Crossref","is-referenced-by-count":4,"title":["The prediction of viscous losses and pressure drop in models of the human airways"],"prefix":"10.1002","volume":"34","author":[{"given":"Andrew K.","family":"Wells","sequence":"first","affiliation":[{"name":"ANSYS UK Ltd.  97 Jubilee Avenue, Milton Park Abingdon Oxon OX14 4RW UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8937-3529","authenticated-orcid":false,"given":"Ian P.","family":"Jones","sequence":"additional","affiliation":[{"name":"ANSYS UK Ltd.  97 Jubilee Avenue, Milton Park Abingdon Oxon OX14 4RW UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian S.","family":"Hamill","sequence":"additional","affiliation":[{"name":"ANSYS UK Ltd.  97 Jubilee Avenue, Milton Park Abingdon Oxon OX14 4RW UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafel","family":"Bordas","sequence":"additional","affiliation":[{"name":"Department of Computer Science University of Oxford, Wolfson Building  Parks Road Oxford OX1 3QD UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,7,19]]},"reference":[{"key":"e_1_2_16_2_1","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.01411"},{"key":"e_1_2_16_3_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00135909"},{"key":"e_1_2_16_4_1","doi-asserted-by":"crossref","DOI":"10.1017\/CBO9780511627156","volume-title":"Lung Mechanics, An Inverse Modeling Approach","author":"Bates JHT","year":"2009"},{"key":"e_1_2_16_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medengphy.2016.11.007"},{"key":"e_1_2_16_6_1","first-page":"225","article-title":"Flow patterns in models of the human airways","volume":"162","author":"Schroter RC","year":"1969","journal-title":"Respiration Physiology"},{"key":"e_1_2_16_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5687(70)90093-9"},{"key":"e_1_2_16_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5687(70)90094-0"},{"key":"e_1_2_16_9_1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0144105","article-title":"Development and analysis of patient\u2010based complete conducting airways models","volume":"10","author":"Bordas R","year":"2015","journal-title":"PloS One"},{"key":"e_1_2_16_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtbi.2012.01.042"},{"key":"e_1_2_16_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/cnm.2577"},{"key":"e_1_2_16_12_1","article-title":"A quasi\u20103D wire approach to model pulmonary airflow in human airways","author":"Kannan R","year":"2016","journal-title":"International Journal for Numerical Methods in Biomedical Engineering."},{"key":"e_1_2_16_13_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00795.2004"},{"key":"e_1_2_16_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2015.03.035"},{"key":"e_1_2_16_15_1","unstructured":"ANSYS CFX release 16 manuals ANSYS Inc; 2016."},{"key":"e_1_2_16_16_1","doi-asserted-by":"crossref","unstructured":"RawMJ.Robustness of coupled algebraic multigrid for the Navier\u2010Stokes equations. 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