{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T01:05:39Z","timestamp":1792458339346,"version":"4.5.0"},"reference-count":28,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2018,7,24]],"date-time":"2018-07-24T00:00:00Z","timestamp":1532390400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Numer Methods Biomed Eng"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Annually, hundreds of thousands of surgical interventions to correct nasal airway obstruction are performed throughout the world. Recent studies have noted that a significant number of patients have persistent symptoms of nasal obstruction postoperatively. In the present work, we introduce a new methodology that raises the success rate of nasal cavity surgery. In this procedure, the surgeon performs virtual surgery on a 3D nasal model of a patient prior to the real surgery. The main goal of the methodology is to guide the surgeon throughout the virtual operation using mathematical estimators based on CFD results. The virtual surgery intervention ends as soon as the estimators fall into a region of a Cartesian coordinate system with a high success probability. This region is defined according to a statistical analysis of estimators corresponding to sets of healthy and diseased cavities. As examples of this application, this study includes 2 surgical operations performed with this innovative methodology on patients with severe nasal obstruction. The patients underwent nasal surgery according to the final nasal geometry revealed by CFD\u2010guided virtual surgery. Currently, both subjects show high degrees of satisfaction.<\/jats:p>","DOI":"10.1002\/cnm.3126","type":"journal-article","created":{"date-parts":[[2018,7,3]],"date-time":"2018-07-03T01:00:00Z","timestamp":1530579600000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Nasal surgery handled by CFD tools"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0888-1984","authenticated-orcid":false,"given":"Enrique","family":"Sanmiguel\u2010Rojas","sequence":"first","affiliation":[{"name":"Escuela de Ingenier\u00edas Industriales, Andaluc\u00eda Tech Universidad of M\u00e1laga  29071 M\u00e1laga Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel Antonio","family":"Burgos","sequence":"additional","affiliation":[{"name":"Departamento de Ingenie\u0155\u0131a T\u00e9rmica y de Fluidos Universidad Polit\u00e9cnica de Cartagena  Cartagena Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Esteban\u2010Ortega","sequence":"additional","affiliation":[{"name":"Departamento de Otorrinolaringolog\u00eda, Hospital Universitario Virgen del Roc\u00edo Universidad de Sevilla  Sevilla Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,7,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2009.171"},{"issue":"2","key":"e_1_2_9_3_1","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/S0030-6665(20)31450-X","article-title":"The systemic effects of nasal obstruction","volume":"22","author":"Kimmelman C","year":"1989","journal-title":"Otolaryngologic Clinics of North America"},{"issue":"2","key":"e_1_2_9_4_1","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0030-6665(20)31437-7","article-title":"The problem of nasal obstruction","volume":"22","author":"Kimmelman CP","year":"1989","journal-title":"Otolaryngologic Clinics of North America"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02439733"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20777"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/194589240401800603"},{"issue":"1","key":"e_1_2_9_8_1","first-page":"24","article-title":"Numerical simulation of intranasal air flow and temperature after resection of the turbinates","volume":"43","author":"Lindemann J","year":"2005","journal-title":"Rhinology"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-006-9094-8"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-008-9556-2"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20585"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2009.0306"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/cnm.2616"},{"key":"e_1_2_9_14_1","unstructured":"SeoA LeeJ KimDH KimSW KimSK.Collaborative three\u2010dimensional virtual nasal surgery. In: Proceedings of the 35th IASTED International Conference. Innsbruck Austria.2016;https:\/\/doi.org\/10.2316\/P.2016.830\u2010053."},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10409-008-0148-z"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21319"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-005-2513-4"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.131.12.1102"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2010.24.3511"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/cnm.2906"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-017-4611-y"},{"issue":"8","key":"e_1_2_9_22_1","first-page":"452","article-title":"Numerical simulation of airflow in the human nose","volume":"261","author":"Weinhold I","year":"2004","journal-title":"European Archives of Oto\u2010Rhino\u2010 Laryngology and Head Neck"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2018.05.016"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25367"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2016.08.014"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-4486.2009.01995.x"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.12881"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-014-3437-0"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2010.24.3428"}],"container-title":["International Journal for Numerical Methods in Biomedical Engineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcnm.3126","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cnm.3126","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T09:07:12Z","timestamp":1693645632000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cnm.3126"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,24]]},"references-count":28,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["10.1002\/cnm.3126"],"URL":"https:\/\/doi.org\/10.1002\/cnm.3126","archive":["Portico"],"relation":{},"ISSN":["2040-7939","2040-7947"],"issn-type":[{"value":"2040-7939","type":"print"},{"value":"2040-7947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,24]]},"assertion":[{"value":"2018-02-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-06-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e3126"}}