{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T12:53:43Z","timestamp":1760705623037,"version":"3.41.2"},"reference-count":48,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T00:00:00Z","timestamp":1536105600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001602","name":"Science Foundation Ireland","doi-asserted-by":"publisher","award":["15\/CDA\/3323"],"award-info":[{"award-number":["15\/CDA\/3323"]}],"id":[{"id":"10.13039\/501100001602","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Numer Methods Biomed Eng"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The current study aims to computationally evaluate the effect of right upper arm position on the geometric and hemodynamic characteristics of the brachial artery (BA) and cephalic vein (CV) and, furthermore, to present in detail the methodology to characterise morphological and hemodynamical healthy vessels. Ten healthy volunteers were analysed in two configurations, the supine (S) and the prone (P) position. Lumen 3D surface models were constructed from images acquired from a non\u2010contrast MRI sequence. Then, the models were used to numerically compute the physiological range of geometric (<jats:italic>n<\/jats:italic>\u00a0=\u00a010) and hemodynamic (<jats:italic>n<\/jats:italic>\u00a0=\u00a03) parameters in the BA and CV. Geometric parameters such as curvature and tortuosity, and hemodynamic parameters based on wall shear stress (WSS) metrics were calculated with the use of computational fluid dynamics. Our results highlight that changes in arm position had a greater impact on WSS metrics of the BA by altering the mean and maximum blood flow rate of the vessel. Whereas, curvature and tortuosity were found not to be significantly different between positions. Inter\u2010variability was associated with antegrade and retrograde flow in BA, and antegrade flow in CV. Shear stress was low and oscillatory shear forces were negligible. This data suggests that deviations from this state may contribute to the risk of accelerated intimal hyperplasia of the vein in arteriovenous fistulas. Therefore, preoperative conditions coupled with post\u2010operative longitudinal data will aid the identification of such relationships.<\/jats:p>","DOI":"10.1002\/cnm.3136","type":"journal-article","created":{"date-parts":[[2018,8,3]],"date-time":"2018-08-03T12:53:14Z","timestamp":1533300794000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Morphological and hemodynamical alterations in brachial artery and cephalic vein. An image\u2010based study for preoperative assessment for vascular access creation"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0206-7773","authenticated-orcid":false,"given":"Nicolas","family":"Aristokleous","sequence":"first","affiliation":[{"name":"Bio\u2010Science and Bio\u2010Engineering Research (BioSciBER), School of Engineering Bernal Institute and the Health Research Institute, University of Limerick, Castletroy  Limerick Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Graeme","family":"Houston","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular and Diabetes Medicine, Ninewells Hospital and Medical School University of Dundee  Dundee UK"},{"name":"NHS Tayside Clinical Radiology, Ninewells Hospital  Dundee UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonard D.","family":"Browne","sequence":"additional","affiliation":[{"name":"Bio\u2010Science and Bio\u2010Engineering Research (BioSciBER), School of Engineering Bernal Institute and the Health Research Institute, University of Limerick, Castletroy  Limerick Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen P.","family":"Broderick","sequence":"additional","affiliation":[{"name":"Bio\u2010Science and Bio\u2010Engineering Research (BioSciBER), School of Engineering Bernal Institute and the Health Research Institute, University of Limerick, Castletroy  Limerick 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