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TMJs are bilateral joints which work as one unit in conducting daily functions such as speaking, mastication, and other activities associated with the movement of the jaw. Issues associated with the TMJs may arise due to various factors\u2014one such factor being the internal load on the TMJ. These issues may contribute to temporomandibular disorders (TMD). This study aims to evaluate the mandibular trajectories and the associated stress changes during the process of opening the mouth on the TMJs of an asymptomatic subject. The mouth opening motion was recorded by a motion capturing system using models of the mandible and maxilla constructed based on the computed tomography (CT). Two discs constructed based on magnetic resonance imaging (MRI). Finite element analysis was performed on the relative motion of the mandible to the maxilla and validated. The process modelled by these displacements provided less than 10% error in terms of deformation. The simulation results indicate that the lateral intermediate zone\u2014the head and neck of the mandible\u2014and the articular eminence sustained the most significant stresses during the mouth opening motion. The results also suggested that the stresses increase as the range of opening increases with the greatest von Mises stress, tensile, and compressive stress found at the position of maximal opening.<\/jats:p>","DOI":"10.1002\/cnm.3373","type":"journal-article","created":{"date-parts":[[2020,5,26]],"date-time":"2020-05-26T10:05:10Z","timestamp":1590487510000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Biomechanical behaviour of temporomandibular joints during opening and closing of the mouth: A 3D finite element analysis"],"prefix":"10.1002","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5404-4912","authenticated-orcid":false,"given":"Jingheng","family":"Shu","sequence":"first","affiliation":[{"name":"Key Lab for Biomechanical Engineering of Sichuan Province Sichuan University  Chengdu 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