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Using computational fluid dynamics, this study aims to investigate the effect of various peristaltic parameters on the motion of an obstacle through a two\u2010dimensional ureter. Methodologically, Incompressible Navier\u2013Stokes equations were utilized as the fluid domain's governing equations, and the Dynamic Mesh method (DM) was employed to simulate the peristaltic and obstacle motion. The peristaltic motion was modeled by a sinusoidal contraction wave propagating alongside the ureter at the physiological speed, and the motion of the obstruction through the ureter, which is caused by the fluid forces applied on its surface, was explored using the equation of Newton's second law. Various test cases of different shapes and sizes were supposed as kidney stones to understand the influence of the peristalsis properties on the stone removal process. The results show that the motion of the kidney stone is highly influenced by the gradient pressure force applied to its surface in the fluid domain. Moreover, investigating the effects of the peristaltic physical properties on the obstacle's motion indicates that the stone's motion is dependent on these parameters. Furthermore, this analysis provides insight into the peristaltic motion effects, assisting physicians in developing new medicines to facilitate the kidney stone removal process based on its shape and size.<\/jats:p>","DOI":"10.1002\/cnm.3800","type":"journal-article","created":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T00:24:05Z","timestamp":1705019045000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Numerical analysis of an obstacle motion in the human ureter using the dynamic mesh approach"],"prefix":"10.1002","volume":"40","author":[{"given":"Saman","family":"Abbasian","sequence":"first","affiliation":[{"name":"Faculty of Mechanical Engineering Tarbiat Modares University Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7387-8434","authenticated-orcid":false,"given":"Reza","family":"Maddahian","sequence":"additional","affiliation":[{"name":"Faculty of Mechanical Engineering Tarbiat Modares University Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,1,11]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_10_2_1","DOI":"10.1115\/1.3564720"},{"doi-asserted-by":"publisher","key":"e_1_2_10_3_1","DOI":"10.1017\/S0022112077001189"},{"doi-asserted-by":"publisher","key":"e_1_2_10_4_1","DOI":"10.1017\/S0022112082002304"},{"doi-asserted-by":"publisher","key":"e_1_2_10_5_1","DOI":"10.1080\/10618560290034681"},{"doi-asserted-by":"publisher","key":"e_1_2_10_6_1","DOI":"10.1017\/S0022112069000899"},{"doi-asserted-by":"publisher","key":"e_1_2_10_7_1","DOI":"10.1017\/S0022112075001760"},{"doi-asserted-by":"publisher","key":"e_1_2_10_8_1","DOI":"10.1017\/S0022112088002149"},{"doi-asserted-by":"publisher","key":"e_1_2_10_9_1","DOI":"10.1017\/jfm.2023.363"},{"doi-asserted-by":"publisher","key":"e_1_2_10_10_1","DOI":"10.1063\/1.5128417"},{"doi-asserted-by":"publisher","key":"e_1_2_10_11_1","DOI":"10.1146\/annurev.fluid.37.061903.175725"},{"doi-asserted-by":"publisher","key":"e_1_2_10_12_1","DOI":"10.1016\/S0895\u20107177(00)00295\u20108"},{"doi-asserted-by":"publisher","key":"e_1_2_10_13_1","DOI":"10.1063\/1.2963530"},{"doi-asserted-by":"publisher","key":"e_1_2_10_14_1","DOI":"10.1016\/j.amc.2009.11.002"},{"doi-asserted-by":"publisher","key":"e_1_2_10_15_1","DOI":"10.1080\/10255842.2014.940332"},{"doi-asserted-by":"publisher","key":"e_1_2_10_16_1","DOI":"10.1556\/APhysiol.96.2009.4.2"},{"doi-asserted-by":"crossref","unstructured":"EghbalA RassoliA FatouraeeN.The Effect of the Ureterovesical Junction on Urinary Peristaltic Flow.Proceeding of IEEE; 106\u2010110.","key":"e_1_2_10_17_1","DOI":"10.1109\/ICBME.2016.7890939"},{"doi-asserted-by":"publisher","key":"e_1_2_10_18_1","DOI":"10.1080\/10255842.2011.581237"},{"doi-asserted-by":"publisher","key":"e_1_2_10_19_1","DOI":"10.22037\/uj.v11i3.2472"},{"doi-asserted-by":"publisher","key":"e_1_2_10_20_1","DOI":"10.1002\/wsbm.1523"},{"doi-asserted-by":"publisher","key":"e_1_2_10_21_1","DOI":"10.1016\/j.cmpb.2021.106378"},{"doi-asserted-by":"publisher","key":"e_1_2_10_22_1","DOI":"10.30919\/es8d734"},{"key":"e_1_2_10_23_1","first-page":"256","article-title":"Ureterdynamic analysis of multiple peristaltic waves on variable diameter ureter","volume":"17","author":"Keni LG","year":"2022","journal-title":"Eng Sci"},{"issue":"4","key":"e_1_2_10_24_1","first-page":"55","article-title":"A nonlinear analysis of urine bolus peristaltic transport from the renal pelvis into the bladder using computational method of fluid\u2010structure interaction","volume":"10","author":"Fatouraee N","year":"2010","journal-title":"Modares Mech Eng"},{"unstructured":"TakaddusAT.Numerical Investigations of Unobstructed and Obstructed Human Ureter Peristalsis [Thesis]. 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