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While extensive clinical and computational literature on aortic and mitral valve replacements is available, PVR's post\u2010procedural haemodynamics in the pulmonary artery and the impact of prosthetic valve dynamics remain significantly understudied. Addressing this gap, we introduce a reduced Fluid\u2013Structure Interaction (rFSI) model, applied for the first time to the pulmonary valve. This model couples a three\u2010dimensional computational representation of pulmonary artery haemodynamics with a one\u2010degree\u2010of\u2010freedom model to account for valve structural mechanics. Through this approach, we analyse patient\u2010specific haemodynamics pre and post PVR. Patient\u2010specific geometries, reconstructed from CT scans, are virtually equipped with a template valve geometry. Boundary conditions for the model are established using a lumped\u2010parameter model, fine\u2010tuned based on clinical patient data. Our model accurately reproduces patient\u2010specific haemodynamic changes across different scenarios: pre\u2010PVR, six months post\u2010PVR, and a follow\u2010up condition after a decade. It effectively demonstrates the impact of valve implantation on sustaining the diastolic pressure gradient across the valve. The numerical results indicate that our valve model is able to reproduce overall physiological and\/or pathological conditions, as preliminary assessed on two different patients. This promising approach provides insights into post\u2010PVR haemodynamics and prosthetic valve effects, shedding light on potential implications for patient\u2010specific outcomes.<\/jats:p>","DOI":"10.1002\/cnm.3846","type":"journal-article","created":{"date-parts":[[2024,7,23]],"date-time":"2024-07-23T05:55:41Z","timestamp":1721714141000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Computational haemodynamics for pulmonary valve replacement by means of a reduced fluid\u2010structure interaction model"],"prefix":"10.1002","volume":"40","author":[{"given":"Elisabetta","family":"Criseo","sequence":"first","affiliation":[{"name":"LaBS, Dipartimento di Chimica, Materiali e Ingegneria Chimica Politecnico di Milano  Milan Italy"},{"name":"Centro Cardiologico Monzino IRCCS  Milan 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