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A finite element model of the lumbar spine (49\u2010year\u2010old asymptomatic female) was used to simulate intervertebral movements (L2\u2013L5) of 127 asymptomatic participants. The data from participants that at least completed a simulation of lumbar vertebral movement during the first 53% of a movement cycle (flexion phase) were used for further analyses. Then, for each vertebral angular motion curve with constant spatial peaks, different temporal patterns were simulated in two stages: (1) in lumbar pattern exchange (LPE), each vertebral angle was simulated by the corresponding vertebrae of other participants data; (2) in vertebral pattern exchange (VPE), vertebral angles were simulated by each other. The <jats:italic>k<\/jats:italic>\u2010mean algorithm was used to cluster two groups of variables; peak and cumulative IDP, in both stages of simulations (i.e., LPE and VPE). In the second stage of the simulation (VPE), Kendall's tau was utilized to consider the relationship between different temporal patterns and IDPs for each individual lumbar level. Cluster analyses showed that the temporal movement pattern did not exhibit any effect on the peak IDP while the cumulative IDP changed significantly for some patterns. Earlier involvement in lumbar motion at any level led to higher IDP in the majority of simulations. There is therefore a possibility of manipulating lumbar IDP by changing the temporal pattern with the same ROM, in which optimal distribution of the loads among lumbar levels may be applied as preventive or treatment interventions. Evaluating load benefits, such as load, on biomechanically relevant lumbar levels, dynamically measured by quantitative fluoroscopy, may help inform interventional exercises.<\/jats:p>","DOI":"10.1002\/cnm.3866","type":"journal-article","created":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T23:34:39Z","timestamp":1728430479000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effect of asymptomatic intervertebral flexion patterns on lumbar disc pressure: A finite element analysis study"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1370-7182","authenticated-orcid":false,"given":"Mehdi","family":"Nematimoez","sequence":"first","affiliation":[{"name":"Department of Sport Biomechanics University of Bojnord  Bojnurd 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