{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:38:50Z","timestamp":1790789930046,"version":"4.1.0"},"reference-count":106,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T00:00:00Z","timestamp":1731283200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Numer Methods Biomed Eng"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Reported in this paper is a cutting\u2010edge computational investigation into the influence of geometric characteristics on abdominal aortic aneurysm (AAA) rupture risk, beyond the traditional measure of maximum aneurysm diameter. A Comprehensive fluid\u2013structure interaction (FSI) analysis was employed to assess risk factors in a range of patient scenarios, with the use of three\u2010dimensional (3D) AAA models reconstructed from patient\u2010specific aortic data and finite element method. Wall shear stress (WSS), and its derivatives such as time\u2010averaged WSS (TAWSS), oscillatory shear index (OSI), relative residence time (RRT) and transverse WSS (transWSS) offer insights into the force dynamics acting on the AAA wall. Emphasis is placed on these WSS\u2010based metrics and seven key geometric indices. By correlating these geometric discrepancies with biomechanical phenomena, this study highlights the novel and profound impact of geometry on risk prediction. This study demonstrates the necessity of a multidimensional assessment approach, future efforts should complement these findings with experimental validations for an applicable approach for clinical use.<\/jats:p>","DOI":"10.1002\/cnm.3884","type":"journal-article","created":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T02:54:12Z","timestamp":1731380052000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Impact of Geometric Attributes on Abdominal Aortic Aneurysm Rupture Risk: An In\u00a0Vivo\n                    <scp>FSI<\/scp>\n                    \u2010Based Study"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6465-1609","authenticated-orcid":false,"given":"Xiaochen","family":"Wang","sequence":"first","affiliation":[{"name":"School of Electrical and Mechanical Engineering University of Adelaide  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4883-0786","authenticated-orcid":false,"given":"Mergen H.","family":"Ghayesh","sequence":"additional","affiliation":[{"name":"School of Electrical and Mechanical Engineering University of Adelaide  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiawen","family":"Li","sequence":"additional","affiliation":[{"name":"School of Electrical and Mechanical Engineering University of Adelaide  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei","family":"Kotousov","sequence":"additional","affiliation":[{"name":"School of Electrical and Mechanical Engineering University of Adelaide  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4099-8146","authenticated-orcid":false,"given":"Anthony C.","family":"Zander","sequence":"additional","affiliation":[{"name":"School of Electrical and Mechanical Engineering University of Adelaide  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph A.","family":"Dawson","sequence":"additional","affiliation":[{"name":"Department of Vascular &amp; Endovascular Surgery Royal Adelaide Hospital  Adelaide South Australia Australia"},{"name":"Trauma Surgery Unit Royal Adelaide Hospital  Adelaide South Australia Australia"},{"name":"Adelaide Medical School University of Adelaide  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Psaltis","sequence":"additional","affiliation":[{"name":"Adelaide Medical School University of Adelaide  Adelaide South Australia Australia"},{"name":"Vascular Research Centre, Lifelong Health Theme South Australian Health &amp; Medical Research Institute (SAHMRI)  Adelaide South Australia Australia"},{"name":"Department of Cardiology Central Adelaide Local Health Network  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,11]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572\u2010018\u20100030\u20107"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2021.03.009"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41569\u2010018\u20100114\u20109"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2016.08.003"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2019.03.051"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2019.12.026"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2023.105922"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2019.00111"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439\u2010019\u201002375\u20101"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1115\/1.4051905"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2013.10.097"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2017.05.014"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2023.01.002"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2021.717593"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2016.12.030"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/cnm.3326"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2009.12.002"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13550\u2010015\u20100153\u20108"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medengphy.2020.01.008"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2023.107790"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2017.10.033"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10237\u2010021\u201001419\u20107"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00270\u2010022\u201003140\u2010z"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euromechflu.2014.02.011"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2018.07.013"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40430\u2010022\u201003480\u20104"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/fld.1763"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/cnm.3736"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.3390\/app12168049"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11517\u2010022\u201002665\u20102"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10237\u2010021\u201001478\u2010w"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00419\u2010021\u201002034\u20109"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439\u2010019\u201002261\u2010w"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010021\u201096512\u20103"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1115\/1.4036826"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medengphy.2018.06.007"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2005.12.013"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1115\/1.4024275"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2015.04.027"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021\u20109290(99)00201\u20108"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2011.02.017"},{"key":"e_1_2_10_43_1","volume-title":"Help System, Mechanical APDL 2022 R2","author":"ANSYS\u00ae Academic Research","year":"2022"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnonlinmec.2020.103530"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnonlinmec.2011.05.001"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnonlinmec.2010.02.003"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnonlinmec.2018.11.010"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2021.07.036"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2020.104079"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2117232119"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnonlinmec.2016.12.013"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1080\/10255840802176396"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1067\/mva.2002.126087"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2008.01.006"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10237\u2010022\u201001618\u2010w"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2019.105185"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compstruc.2006.08.041"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1115\/1.4037857"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1115\/1.4001886"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2017.06.005"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13239\u2010018\u201000385\u2010z"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2021.104882"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2019.105064"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2022.106826"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2023.107598"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.2174\/1877613211303010006"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1115\/1.3127256"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439\u2010017\u20101837\u20101"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0187421"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2011.06.017"},{"key":"e_1_2_10_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2017.06.029"},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnonlinmec.2023.104517"},{"key":"e_1_2_10_73_1","doi-asserted-by":"publisher","DOI":"10.1115\/1.4005176"},{"key":"e_1_2_10_74_1","doi-asserted-by":"publisher","DOI":"10.1115\/1.4045268"},{"key":"e_1_2_10_75_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2015.0852"},{"key":"e_1_2_10_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2020.105916"},{"key":"e_1_2_10_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2023.107418"},{"key":"e_1_2_10_78_1","doi-asserted-by":"publisher","DOI":"10.3390\/bioengineering10050540"},{"key":"e_1_2_10_79_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439\u2010010\u20100175\u20103"},{"key":"e_1_2_10_80_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439\u2010018\u201002116\u2010w"},{"key":"e_1_2_10_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2015.01.040"},{"key":"e_1_2_10_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2021.104385"},{"key":"e_1_2_10_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvscit.2020.01.014"},{"key":"e_1_2_10_84_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/472564"},{"key":"e_1_2_10_85_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.21.2035"},{"key":"e_1_2_10_86_1","doi-asserted-by":"publisher","DOI":"10.1067\/mva.2002.125478"},{"key":"e_1_2_10_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medengphy.2016.03.003"},{"key":"e_1_2_10_88_1","doi-asserted-by":"publisher","DOI":"10.1114\/1.140"},{"key":"e_1_2_10_89_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439\u2010010\u20109949\u2010x"},{"key":"e_1_2_10_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2023.106609"},{"key":"e_1_2_10_91_1","doi-asserted-by":"publisher","DOI":"10.1177\/0954411912444080"},{"key":"e_1_2_10_92_1","doi-asserted-by":"publisher","DOI":"10.1002\/cnm.3555"},{"key":"e_1_2_10_93_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13239\u2010016\u20100287\u20105"},{"key":"e_1_2_10_94_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10237\u2010019\u201001269\u20104"},{"key":"e_1_2_10_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2021.104652"},{"key":"e_1_2_10_96_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00897.2003"},{"key":"e_1_2_10_97_1","doi-asserted-by":"publisher","DOI":"10.1115\/1.3127252"},{"key":"e_1_2_10_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2016.11.035"},{"key":"e_1_2_10_99_1","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.113.301826"},{"key":"e_1_2_10_100_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01047.2006"},{"key":"e_1_2_10_101_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A3558"},{"key":"e_1_2_10_102_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.110.592923"},{"key":"e_1_2_10_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2022.107174"},{"key":"e_1_2_10_104_1","doi-asserted-by":"crossref","unstructured":"G.Jalalahmadi M.Helguera andC. A.Linte \u201cA Machine Leaning Approach for Abdominal Aortic Aneurysm Severity Assessment Using Geometric Biomechanical and Patient\u2010Specific Historical Clinical Features \u201dinMedical Imaging 2020: Biomedical Applications in Molecular Structural and Functional Imaging (SPIE 2020) 266\u2013271.","DOI":"10.1117\/12.2549277"},{"key":"e_1_2_10_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2021.104394"},{"key":"e_1_2_10_106_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2019.12.027"},{"key":"e_1_2_10_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2021.106082"}],"container-title":["International Journal for Numerical Methods in Biomedical Engineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cnm.3884","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T11:32:02Z","timestamp":1750419122000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cnm.3884"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,11]]},"references-count":106,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1002\/cnm.3884"],"URL":"https:\/\/doi.org\/10.1002\/cnm.3884","archive":["Portico"],"relation":{},"ISSN":["2040-7939","2040-7947"],"issn-type":[{"value":"2040-7939","type":"print"},{"value":"2040-7947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,11]]},"assertion":[{"value":"2024-04-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e3884"}}