{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T05:22:18Z","timestamp":1768713738508,"version":"3.49.0"},"reference-count":43,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001843","name":"Science and Engineering Research Board","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001843","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Numer Methods Biomed Eng"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Magnetic nanoparticles for hyperthermic cancer treatment have gained significant attention in recent years. Magnetic hyperthermia ablates malignant cells by dissipating heat from magnetic nanoparticles (MNPs) when subjected to an alternate magnetic field. Living tissues are highly non\u2010homogeneous, and non\u2010Fourier thermal behavior in biological tissue has been experimentally observed. In the present work, two important treatment parameters\u2014the therapeutic temperature distribution and the degree of thermal damage to a three\u2010dimensional, randomly shaped tumor encompassed by healthy tissue during the MNP hyperthermia treatment procedure\u2014have been determined computationally. A three\u2010dimensional space\u2013time fractional dual\u2010phase lag model has been discussed to simulate heat transmission in the tissues. The considered model is solved using the meshless method based on the RBF function and shifted Chebyshev polynomials in spatial and temporal directions, respectively. The influence of fractional derivatives (), phase lag times (), and heat source parameters () on the thermal damage in tumors has been investigated, and it has been observed that these parameters have significant effects on the distribution of temperature and thermal damage to the tumor tissue.<\/jats:p>","DOI":"10.1002\/cnm.70083","type":"journal-article","created":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T00:57:12Z","timestamp":1755046632000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Study on Thermal Damage in\n                    <scp>3D<\/scp>\n                    Tumor During Magnetic Nanoparticle Hyperthermia Using Space\u2013Time Fractional Dual Phase Lag Bioheat Model"],"prefix":"10.1002","volume":"41","author":[{"given":"Bhagya Shree","family":"Meena","sequence":"first","affiliation":[{"name":"Department of Mathematics and Statistics Manipal University Jaipur  Jaipur India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4498-5123","authenticated-orcid":false,"given":"Sushil","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Mathematics S. V. National Institute of Technology Surat  Surat India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,12]]},"reference":[{"issue":"2","key":"e_1_2_11_2_1","first-page":"341","article-title":"Hyperthermia in Cancer Therapy: Where Are We Today and Where Are We Going?","volume":"68","author":"Steeves R. 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