{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T05:59:36Z","timestamp":1789192776557,"version":"build-2803163510"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,12,9]],"date-time":"2020-12-09T00:00:00Z","timestamp":1607472000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Reports"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cystic adrenal lesions are rare and uncommon manifestation with few cases reported so far. Different types of adrenal cysts have been described with heterogeneous etiology and overlapping clinical findings, ranging from benign to malignant cystic neoplasm. They are usually asymptomatic or may rarely present with abdominal pain or fullness. Optimum management of adrenal cysts still remain controversial, owing to its low incidence. In this study, we report our institutional experience on diagnosis and management of different histological types of cystic adrenal lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Cases<\/jats:title><jats:p>During 4\u2009years period, 55 patients underwent adrenalectomy with five cases presenting as adrenal cysts. All the five patients were biochemically nonfunctional and underwent adrenalectomy (laparoscopic anterior n = 2, retroperitoneoscopic approach n = 1, and open anterior transperitoneal approach n = 2). The primary indications for surgery were larger size and\/or suspicion of malignancy. Histological evaluation revealed two epithelial cysts, one endothelial cyst, one pseudocyst, and a very rare case of adrenocortical carcinoma arising in a pseudocyst.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Cystic adrenal lesions are rare with varied etiologic and clinical presentation that may sometimes lead to diagnostic and management dilemma. These cases must undergo biochemical and radiological evaluation to rule out underlying malignancy followed by referral for surgical intervention.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cnr2.1314","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T06:48:45Z","timestamp":1607582925000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Cystic adrenal lesions: A report of five cases"],"prefix":"10.1002","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4517-6929","authenticated-orcid":false,"given":"Divya","family":"Goel","sequence":"first","affiliation":[{"name":"Department of Pathology King George's Medical University  Lucknow Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loreno","family":"Enny","sequence":"additional","affiliation":[{"name":"Department of Endocrine surgery King George's Medical University  Lucknow Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1783-7689","authenticated-orcid":false,"given":"Chanchal","family":"Rana","sequence":"additional","affiliation":[{"name":"Department of Pathology King George's Medical University  Lucknow Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pooja","family":"Ramakant","sequence":"additional","affiliation":[{"name":"Department of Endocrine surgery King George's Medical University  Lucknow Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kulranjan","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Endocrine surgery King George's Medical University  Lucknow Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suresh","family":"Babu","sequence":"additional","affiliation":[{"name":"Department of Pathology King George's Medical University  Lucknow Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anand","family":"Mishra","sequence":"additional","affiliation":[{"name":"Department of Endocrine surgery King George's Medical University  Lucknow Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.07.2799"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-003-4547-8"},{"key":"e_1_2_9_4_1","first-page":"1401e1406","article-title":"Cysts of the adrenal gland: revision of a 15\u2010year experience","volume":"21","author":"Cavallaro A","year":"2001","journal-title":"Anticancer Res."},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(89)90153-6"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.20555"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2014.11.023"},{"key":"e_1_2_9_8_1","first-page":"751","article-title":"Adrenal gland cyst. 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