{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T02:43:14Z","timestamp":1780454594063,"version":"3.54.1"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,2,26]],"date-time":"2021-02-26T00:00:00Z","timestamp":1614297600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Reports"],"published-print":{"date-parts":[[2021,6]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Febrile neutropenia is a serious complication of chemotherapy. The Multinational Association for Supportive Care in Cancer (MASCC) risk index score identifies patients at low risk of serious complications. Outpatient management programs have been successfully piloted in other Australian metropolitan cancer centers.<\/jats:p><\/jats:sec>Aim<\/jats:title>To assess current management of febrile neutropenia at our regional cancer center and determine potential impacts of an outpatient management program.<\/jats:p><\/jats:sec>Method<\/jats:title>We performed a retrospective review of medical records for all patients admitted at our regional institution with febrile neutropenia between 1 January 2016, and 31 December 2018. We collected information regarding patient characteristics, determined the MASCC risk index score, and if low risk, we determined the eligibility for outpatient care and potential reduction in length of stay and cost benefit.<\/jats:p><\/jats:sec>Results<\/jats:title>A total of 98 hospital admissions were identified. Of these, 66 had a MASCC low\u2010risk index score. Fifty\u2010eight patients met the eligibility criteria for outpatient management. Seventy\u2010one percent were female. The most common tumor type was breast cancer. Forty\u2010eight percent were treated with curative intent. The median length of stay was 3\u2009days. The median potential reduction in length of stay for each admission was 2\u2009days. The total potential reduction in length of stay was 198\u2009days. No admission resulted in serious complications.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>This review demonstrates a significant number of hospital admission days can be avoided. We intend to conduct a prospective pilot study at our center to institute an outpatient management program for such low\u2010risk patients with potential reduction in hospital length of stay. This will have significant implications on health resource usage, service provision planning, and patient quality of life.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cnr2.1345","type":"journal-article","created":{"date-parts":[[2021,2,26]],"date-time":"2021-02-26T13:39:06Z","timestamp":1614346746000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Potential reduction of hospital stay length with outpatient management of low\u2010risk febrile neutropenia in a regional cancer center"],"prefix":"10.1002","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3044-1707","authenticated-orcid":false,"given":"Mike","family":"Nguyen","sequence":"first","affiliation":[{"name":"Medical Oncology St Vincent's Hospital Melbourne Fitzroy Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tate","family":"Jacobson","sequence":"additional","affiliation":[{"name":"Department of Medicine Peninsula Health Frankston Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Torres","sequence":"additional","affiliation":[{"name":"Medical Oncology Goulburn Valley Health Shepparton Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alysson","family":"Wann","sequence":"additional","affiliation":[{"name":"Medical Oncology Goulburn Valley Health Shepparton Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,2,26]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.21847"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2000.18.16.3038"},{"issue":"3","key":"e_1_2_11_4_1","first-page":"CD009031","article-title":"Outpatient treatment for people with cancer who develop a low\u2010risk febrile neutropaenic event","volume":"1","author":"Rivas\u2010Ruiz R","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1200\/JOP.18.00016"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdw325"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.2010.02339.x"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-017-3921-3"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/imj.13313"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/imj.12251"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/imj.12228"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/imj.12117"},{"key":"e_1_2_11_13_1","unstructured":"Department of Health and Human Services. Policy and funding guidelines 2019\u201320.2019.https:\/\/www.dhhs.vic.gov.au\/sites\/default\/files\/documents\/201908\/Policy%20and%20Funding%20Guidelines%202019-20.pdf. Accessed January 29 2021."},{"key":"e_1_2_11_14_1","unstructured":"The Independent Hospital Pricing Authority. National Efficient Price Determination 2020\u201321.2020.https:\/\/www.ihpa.gov.au\/publications\/national-efficient-price-determination-2019-20. 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