{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:19:19Z","timestamp":1791231559277,"version":"4.1.0"},"reference-count":39,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T00:00:00Z","timestamp":1634774400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000521","name":"Canadian Cancer Society","doi-asserted-by":"publisher","award":["707031"],"award-info":[{"award-number":["707031"]}],"id":[{"id":"10.13039\/501100000521","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Reports"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Children with cancer are increasingly using cannabis therapeutically.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>The purpose of this study was to determine the perspectives and practices of pediatric oncologists and palliative care physicians regarding the use of cannabis for medical purposes among children with cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A self\u2010administered, voluntary, cross\u2010sectional, deidentified online survey was sent to all pediatric oncologists and palliative care physicians in Canada between June and August 2020. Survey domains included education, knowledge, and concerns about cannabis, views on its effectiveness, and the importance of cannabis\u2010related research. Data were analyzed using descriptive statistics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 122\/259 (47.1%) physicians completed the survey. Although 62.2% of the physicians completed some form of training about medical cannabis, nearly all (95.8%) desired to know more about the dosing, side effects, and safety of cannabis. Physicians identified a potential role of cannabis in the management of nausea and vomiting (85.7%), chronic pain (72.3%), cachexia\/poor appetite (67.2%), and anxiety or depression (42.9%). Only four (0.3%) physicians recognized cannabis to be potentially useful as an anticancer agent. Nearly all physicians reported that cannabis\u2010related research for symptom relief is essential (91.5%) in pediatric oncology, whereas 51.7% expressed that future studies are necessary to determine the anticancer effects of cannabis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our findings indicate that most pediatric oncologists and palliative care physicians recognize a potential role for cannabis in symptom control in children with cancer. Well\u2010conducted studies are required to create evidence for cannabis use and promote shared decision making with pediatric oncology patients and their caregivers.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cnr2.1551","type":"journal-article","created":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T14:36:44Z","timestamp":1634827004000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Perspectives of pediatric oncologists and palliative care physicians on the therapeutic use of cannabis in children with cancer"],"prefix":"10.1002","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6071-0042","authenticated-orcid":false,"given":"Sapna","family":"Oberoi","sequence":"first","affiliation":[{"name":"Department of Pediatrics and Child Health University of Manitoba Winnipeg Canada"},{"name":"Department of Pediatric Hematology\u2010Oncology CancerCare Manitoba Winnipeg Canada"},{"name":"Children's Hospital Research Institute of Manitoba Winnipeg Manitoba Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer L. P.","family":"Protudjer","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health University of Manitoba Winnipeg Canada"},{"name":"Children's Hospital Research Institute of Manitoba Winnipeg Manitoba Canada"},{"name":"George and Fay Yee Centre for Healthcare Innovation Winnipeg Canada"},{"name":"Department Foods and Human Nutritional Sciences University of Manitoba Winnipeg Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5090-8987","authenticated-orcid":false,"given":"Adam","family":"Rapoport","sequence":"additional","affiliation":[{"name":"Paediatric Advanced Care Team Hospital for Sick Children Toronto Ontario Canada"},{"name":"Emily's House Children's Hospice Toronto Ontario Canada"},{"name":"Department of Paediatrics Faculty of Medicine, University of Toronto Toronto Ontario Canada"},{"name":"Department of Family &amp; Community Medicine Faculty of Medicine, University of Toronto Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8005-2641","authenticated-orcid":false,"given":"Shahrad R.","family":"Rassekh","sequence":"additional","affiliation":[{"name":"Division of Oncology\/Hematology\/BMT, Department of Pediatrics University of British Columbia Vancouver Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce","family":"Crooks","sequence":"additional","affiliation":[{"name":"Pediatric Hematology\/Oncology &amp; Medical Education IWK Health Centre Halifax Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harold","family":"Siden","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Faculty of Medicine University of British Columbia Vancouver Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Decker","sequence":"additional","affiliation":[{"name":"Department of Community Health Sciences University of Manitoba Winnipeg Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5614-7445","authenticated-orcid":false,"given":"Prasanna","family":"Ananth","sequence":"additional","affiliation":[{"name":"Section of Pediatric Hematology\/Oncology, Department of Pediatrics Yale School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacy","family":"Chapman","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health University of Manitoba Winnipeg Canada"},{"name":"Department of Pediatric Hematology\u2010Oncology CancerCare Manitoba Winnipeg Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynda G.","family":"Balneaves","sequence":"additional","affiliation":[{"name":"College of Nursing University of Manitoba Winnipeg Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2015-0615","authenticated-orcid":false,"given":"Magimairajan Issai","family":"Vanan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health University of Manitoba Winnipeg Canada"},{"name":"Department of Pediatric Hematology\u2010Oncology CancerCare Manitoba Winnipeg Canada"},{"name":"Children's Hospital Research Institute of Manitoba Winnipeg Manitoba Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren E.","family":"Kelly","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health University of Manitoba Winnipeg Canada"},{"name":"Children's Hospital Research Institute of Manitoba Winnipeg Manitoba Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,10,21]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"National Institute on Drug Abuse.Marijuana. 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