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The objective of this study was to assess the safety of CRS\/HIPEC in this cohort of patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case<\/jats:title><jats:p>Five PHIV were identified, four of whom underwent CRS\/HIPEC. Primary sites of disease were low\u2010grade appendiceal mucinous tumors in three patients and peritoneal mesothelioma in the other. Operative time ranged from 7 to 14 h. One patient developed a Clavien grade II complication postoperatively. There was no instance of neutropenia identified. One patient died of disease 19 months after surgery; the remaining three patients are alive 11, 21, and 33 months postoperatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study demonstrates that CRS\/HIPEC can be performed in PHIV without prohibitive complications and operative recovery approximates that of non\u2010HIV patients. Though more study is needed, HIV should not preclude a patient from being offered CRS\/HIPEC.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cnr2.1667","type":"journal-article","created":{"date-parts":[[2022,7,23]],"date-time":"2022-07-23T05:04:56Z","timestamp":1658552696000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Safe performance of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in patients with <scp>HIV<\/scp> infection"],"prefix":"10.1002","volume":"5","author":[{"given":"Anna","family":"Coghill","sequence":"first","affiliation":[{"name":"Center for Immunization and Infection Research in Cancer Moffitt Cancer Center  Tampa Florida USA"},{"name":"Cancer Epidemiology Program Moffitt Cancer Center  Tampa Florida USA"},{"name":"Department of Oncologic Sciences, Morsani College of Medicine University of South Florida  Tampa Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian","family":"Sanchez","sequence":"additional","affiliation":[{"name":"Department of Oncologic Sciences, Morsani College of Medicine University of South Florida  Tampa Florida USA"},{"name":"Department of Gastrointestinal Oncology Moffitt Cancer Center  Tampa Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sweta","family":"Sinha","sequence":"additional","affiliation":[{"name":"Cancer Epidemiology Program Moffitt Cancer Center  Tampa Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer B.","family":"Permuth","sequence":"additional","affiliation":[{"name":"Cancer Epidemiology Program Moffitt Cancer Center  Tampa Florida USA"},{"name":"Department of Oncologic Sciences, Morsani College of Medicine University of South Florida  Tampa Florida USA"},{"name":"Department of Gastrointestinal Oncology Moffitt Cancer Center  Tampa Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle","family":"Laskowitz","sequence":"additional","affiliation":[{"name":"Department of Oncologic Sciences, Morsani College of Medicine University of South Florida  Tampa Florida USA"},{"name":"Department of Gastrointestinal Oncology Moffitt Cancer Center  Tampa Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2679-6302","authenticated-orcid":false,"given":"Benjamin D.","family":"Powers","sequence":"additional","affiliation":[{"name":"Department of Oncologic Sciences, Morsani College of Medicine University of South Florida  Tampa Florida USA"},{"name":"Department of Gastrointestinal Oncology Moffitt Cancer Center  Tampa Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2012-2238","authenticated-orcid":false,"given":"Sean P.","family":"Dineen","sequence":"additional","affiliation":[{"name":"Department of Oncologic Sciences, Morsani College of Medicine University of South Florida  Tampa Florida USA"},{"name":"Department of Gastrointestinal Oncology Moffitt Cancer Center  Tampa Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,7,22]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.37.1039"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-008-9966-2"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1642052"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.25939"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-020-05402-8"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.32868"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2019.09.017"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.32874"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.7326\/M17-2499"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa1016"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.32158"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2019.1742"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32835ad56e"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.54.8644"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-86081-w"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.140.10.961"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-015-2994-8"},{"key":"e_1_2_8_19_1","unstructured":"Ending the HIV Epidemic in the U.S (EHE).2021. 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