{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T09:43:54Z","timestamp":1753868634620,"version":"3.41.2"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,10,27]],"date-time":"2022-10-27T00:00:00Z","timestamp":1666828800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Reports"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Acceptability and tolerance of chemotherapy on patients treated for breast cancer remain challenging. Complementary approaches such as hypnosis may have a favorable impact both at the time of announcing and during chemotherapy, due to the notorious anxiety, distress, and self\u2010perceived dysfunction. The objective of the study was that the patients complied with at least four self\u2010hypnosis sessions out of the six cycles of chemotherapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This open, prospective longitudinal study assessed feasibility of compliance to self\u2010hypnosis during chemotherapy in an outpatients setting. Training sessions were given by a hypnotherapist. Throughout each cycle of chemotherapy, the patient had to use self\u2010hypnosis to better control her anxiety or any difficulties. Nurses could offer help to the patient. Chemotherapy\u2010associated side effects were evaluated through the NCI\u2010Common Toxicity Criteria for Adverse Events v 4.03; moreover, side effects as pain, nausea, vomiting, fatigue, and anxiety were also evaluated during chemotherapy using a visual analogic scale. Health\u2010related quality of life, emotional distress (anxiety and depression), and cancer\u2010related fatigue were assessed (at inclusion, end of chemotherapy and 3\u00a0months later) using the EORTC QLQ\u2010C30 and QLQ\u2010BR23, HADS and MFI\u201020 questionnaires, respectively. The number of patients screened and actually included in the study was reported, as the reasons for refusal.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010five patients were included with a median age of 55\u2009years (35\u201378). All patients received a hypnosis training session. The overall compliance with self\u2010hypnosis was 68.6% (95% CI: 50.7%\u201383.2%), meaning that more than two thirds of patients performed at least four sessions of self\u2010hypnosis. According to NCI\u2010CTCAE, Grade 2 nausea and vomiting was observed in 45.7% and 22.9%, respectively, Grade 2 fatigue in 62.9%. Based on the HADS questionnaire, anxiety increased at the end of the chemotherapy and returned to the initial value 3\u00a0months later (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.97) whereas depression significantly decrease 3\u00a0months after the end of chemotherapy with respect to the inclusion (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.003). Role, emotional, and cognitive functioning were slightly affected throughout the treatment, in contrast to dyspnea or physical functioning.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our study showed that self\u2010hypnosis was feasible on patients newly diagnosed for breast cancer receiving chemotherapy.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cnr2.1732","type":"journal-article","created":{"date-parts":[[2022,10,28]],"date-time":"2022-10-28T02:59:31Z","timestamp":1666925971000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Hypnosis on patients treated with adjuvant chemotherapy for breast cancer: A feasibility study"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1910-4777","authenticated-orcid":false,"given":"Michel","family":"Fabbro","sequence":"first","affiliation":[{"name":"Medical Oncology Department Montpellier Cancer Institute (ICM), University of Montpellier  Montpellier France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Jacot","sequence":"additional","affiliation":[{"name":"Medical Oncology Department Montpellier Cancer Institute (ICM), University of Montpellier  Montpellier France"},{"name":"Institut de Recherche en Canc\u00e9rologie de Montpellier (IRCM), Inserm U1194, University of Montpellier  Montpellier France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Jarlier","sequence":"additional","affiliation":[{"name":"Biometrics Unit Montpellier Cancer Institute (ICM), University of Montpellier  Montpellier France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00e9verine","family":"Guiu","sequence":"additional","affiliation":[{"name":"Medical Oncology Department Montpellier Cancer Institute (ICM), University of Montpellier  Montpellier France"},{"name":"Institut de Recherche en Canc\u00e9rologie de Montpellier (IRCM), Inserm U1194, University of Montpellier  Montpellier France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V\u00e9ronique","family":"D'Hondt","sequence":"additional","affiliation":[{"name":"Medical Oncology Department Montpellier Cancer Institute (ICM), University of Montpellier  Montpellier France"},{"name":"Institut de Recherche en Canc\u00e9rologie de Montpellier (IRCM), Inserm U1194, University of Montpellier  Montpellier France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"St\u00e9phane","family":"Pouderoux","sequence":"additional","affiliation":[{"name":"Medical Oncology Department Montpellier Cancer Institute (ICM), University of Montpellier  Montpellier France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrice","family":"Champoiral","sequence":"additional","affiliation":[{"name":"Psycho\u2010Oncology Unit Montpellier Cancer Institute (ICM), University of Montpellier  Montpellier 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