{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T09:44:03Z","timestamp":1753868643045,"version":"3.41.2"},"reference-count":9,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T00:00:00Z","timestamp":1685491200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Reports"],"published-print":{"date-parts":[[2023,8]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Hodgkin lymphoma (HL) is diagnosed definitively by biopsy, and treatment is based on stage. Owing to the nature of the disease, post\u2010treatment efficacy is determined mainly by fluorodeoxyglucose\u2010positron emission tomography\/computed tomography, and the efficacy of treatment is not confirmed by histopathology. We report a case of tongue cancer after treatment for HL, in which a post\u2010treatment lymph node with complete remission was histopathologically confirmed by neck dissection.<\/jats:p><\/jats:sec>Case<\/jats:title>The patient was a 74\u2010year\u2010old man who was referred to our hospital for cancer on the right side of his tongue. He had previously undergone chemotherapy for HL involving the right side of his neck and achieved complete remission. Because he had cT3N2cM0 tongue cancer, glossectomy and bilateral neck dissection were performed. Surprisingly, histopathological examination revealed that there was neither metastatic lymph nodes nor lymphoma cells in his right neck. Moreover, there was no lymphatic structure in his remnant lymph nodes.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>This was a rare case in which complete remission of HL was confirmed by histopathological analysis. The absence of lymph node structure and lymphatic flow led to contralateral neck lymph node metastases of tongue cancer.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cnr2.1838","type":"journal-article","created":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T09:25:45Z","timestamp":1685525145000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A case of complete remission of H<\/scp>odgkin lymphoma confirmed histopathologically by neck dissection"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9212-0445","authenticated-orcid":false,"given":"Yu","family":"Ohashi","sequence":"first","affiliation":[{"name":"Division of Oral and Maxillofacial Surgery, Department of Reconstructive Oral and Maxillofacial Surgery Iwate Medical University, School of Dentistry Morioka Iwate Japan"},{"name":"Head and Neck Cancer Center Iwate Medical University Hospital Yahaba Iwate Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyoto","family":"Shiga","sequence":"additional","affiliation":[{"name":"Head and Neck Cancer Center Iwate Medical University Hospital Yahaba Iwate Japan"},{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Iwate Medical University, School of Medicine Yahaba Iwate Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsunori","family":"Katagiri","sequence":"additional","affiliation":[{"name":"Head and Neck Cancer Center Iwate Medical University Hospital Yahaba Iwate Japan"},{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Iwate Medical University, School of Medicine Yahaba Iwate Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Saito","sequence":"additional","affiliation":[{"name":"Head and Neck Cancer Center Iwate Medical University Hospital Yahaba Iwate Japan"},{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Iwate Medical University, School of Medicine Yahaba Iwate Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shin\u2010ichi","family":"Oikawa","sequence":"additional","affiliation":[{"name":"Head and Neck Cancer Center Iwate Medical University Hospital Yahaba Iwate Japan"},{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Iwate Medical University, School of Medicine Yahaba Iwate Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kodai","family":"Tsuchida","sequence":"additional","affiliation":[{"name":"Head and Neck Cancer Center Iwate Medical University Hospital Yahaba Iwate Japan"},{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Iwate Medical University, School of Medicine Yahaba Iwate Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Miyaguchi","sequence":"additional","affiliation":[{"name":"Head and Neck Cancer Center Iwate Medical University Hospital Yahaba Iwate Japan"},{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Iwate Medical University, School of Medicine Yahaba Iwate Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiro","family":"Kusaka","sequence":"additional","affiliation":[{"name":"Head and Neck Cancer Center Iwate Medical University Hospital Yahaba Iwate Japan"},{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Iwate Medical University, School of Medicine Yahaba Iwate Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Yamada","sequence":"additional","affiliation":[{"name":"Division of Oral and Maxillofacial Surgery, Department of Reconstructive Oral and Maxillofacial Surgery Iwate Medical University, School of Dentistry Morioka Iwate Japan"},{"name":"Head and Neck Cancer Center Iwate Medical University Hospital Yahaba Iwate Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,5,31]]},"reference":[{"key":"e_1_2_12_2_1","unstructured":"RiesLAG YoungJL KeelGE EisnerMP LinYD HornerM\u2010J.SEER survival monograph: cancer survival among adults: U.S. SEER program 1988\u20102001 patient and tumor characteristics. NIH Pub. No. 07\u20106215. Vol2007.National Cancer Institute SEER Program."},{"key":"e_1_2_12_3_1","unstructured":"NCCN.Clinical practice guidelines in oncology Hodgkin lymphoma version 2.2023. Accessed November 8 2022.https:\/\/www.nccn.org\/professionals\/physician_gls\/pdf\/hodgkins.pdf"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2010.529208"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2012.677535"},{"key":"e_1_2_12_6_1","first-page":"1225","volume-title":"Otolaryngology\u2010Head and Neck Surgery","author":"Baker SR","year":"1993"},{"key":"e_1_2_12_7_1","first-page":"135","volume-title":"The Lymphatics in Cancer","author":"Haagensen CD","year":"1972"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000505830"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/17474086.2020.1746183"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-022-01717-8"}],"container-title":["Cancer Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cnr2.1838","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T21:23:14Z","timestamp":1692566594000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cnr2.1838"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,31]]},"references-count":9,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["10.1002\/cnr2.1838"],"URL":"https:\/\/doi.org\/10.1002\/cnr2.1838","archive":["Portico"],"relation":{},"ISSN":["2573-8348","2573-8348"],"issn-type":[{"type":"print","value":"2573-8348"},{"type":"electronic","value":"2573-8348"}],"subject":[],"published":{"date-parts":[[2023,5,31]]},"assertion":[{"value":"2023-01-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e1838"}}