{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T13:41:44Z","timestamp":1782135704856,"version":"3.54.5"},"reference-count":36,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T00:00:00Z","timestamp":1685491200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Reports"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The survival rate of adult patients with Hodgkin lymphoma (HL) depends on the responses to standard chemotherapy, radiotherapy, or combined therapy. Resource\u2010limited countries face numerous obstacles in supporting patients with HL who undergo chemotherapy, especially in advanced stages.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To analyze the survival outcomes of adult patients with HL after combined\u2010modality treatment (CMT) with involved\u2010field or non\u2010involved\u2010field radiotherapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>We retrospectively reviewed the medical records of 90 adult patients with HL who received CMT at Rajavithi Hospital, Bangkok between 2007 and 2021. Patients with stage I\u2010IV disease received different therapies depending on their risk group. The risk groups were evaluated according to initial response, bulky disease, and B symptoms. Patients (n\u2009=\u200990) who underwent CMT were followed up for 34.7\u2009months (range, 1\u2013141\u2009months). The median follow\u2010up periods of early and advanced\u2010stage patients were 53.1\u2009months and 23.5\u2009months, respectively. The estimated 5\u2010year overall survival (OS) and progression\u2010free survival (PFS) rates of patients with advanced\u2010stage diseases were 85% and 62%, respectively. There was a difference in the 3\u2010year overall survival among advance\u2010stage patients who underwent ABVD (94%) compared to those administered BEACOPPesc (50%), and the 3\u2010year PFS (84%) among patients who underwent ABVD was higher than that among those administered BEACOPPesc (66%). Radiotherapy increased toxicity but did not improve the survival rate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Chemotherapy administered to patients with advanced\u2010stage adult HL was more effective than BEACOPPesc when ABVD was administered. Our findings are relevant for hospitals with limited resources.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cnr2.1839","type":"journal-article","created":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T09:27:17Z","timestamp":1685525237000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Survival rates of adult patients with <scp>H<\/scp>odgkin lymphoma who underwent <scp>ABVD<\/scp> versus escalated <scp>BEACOPP<\/scp> in a resource\u2010limited country: An observational study"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8519-4160","authenticated-orcid":false,"given":"Tawatchai","family":"Suwanban","sequence":"first","affiliation":[{"name":"Division of Hematology, Department of Medicine, Rajavithi Hospital College of Medicine, Rangsit University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1956-1097","authenticated-orcid":false,"given":"Supat","family":"Chamnanchanunt","sequence":"additional","affiliation":[{"name":"Division of Hematology, Department of Medicine, Rajavithi Hospital College of Medicine, Rangsit University  Bangkok Thailand"},{"name":"Department of Clinical Tropical Medicine, Faculty of Tropical Medicine Mahidol University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8287-2096","authenticated-orcid":false,"given":"Pravinwan","family":"Thungthong","sequence":"additional","affiliation":[{"name":"Division of Hematology, Department of Medicine, Rajavithi Hospital College of Medicine, Rangsit University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7158-8313","authenticated-orcid":false,"given":"Chajchawan","family":"Nakhahes","sequence":"additional","affiliation":[{"name":"Division of Hematology, Department of Medicine, Rajavithi Hospital College of Medicine, Rangsit University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunapa","family":"Iam\u2010arunthai","sequence":"additional","affiliation":[{"name":"Division of Hematology, Department of Medicine, Rajavithi Hospital College of Medicine, Rangsit University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tananchai","family":"Akrawikrai","sequence":"additional","affiliation":[{"name":"Division of Hematology, Department of Medicine, Rajavithi Hospital College of Medicine, Rangsit University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8887-4292","authenticated-orcid":false,"given":"Udomsak","family":"Bunworasate","sequence":"additional","affiliation":[{"name":"Division of Hematology, Department of Medicine, Faculty of Medicine Chulalongkorn University  Bangkok Thailand"},{"name":"Research Unit in Translational Hematology, Faculty of Medicine Chulalongkorn University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,31]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.27033"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552\u2010018\u20101025\u20100"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17051783"},{"key":"e_1_2_10_5_1","unstructured":"National Comprehensive Cancer Network.Hodgkin Lymphoma \u2013 NCCN Clinical Practice Guidline in Oncology National Comprehensive Cancer Network. 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