{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T08:59:11Z","timestamp":1789203551748,"version":"build-2803163510"},"reference-count":34,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T00:00:00Z","timestamp":1696204800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Reports"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Surgical complications and particularly infections after digestive cancer surgery remain a major health and economic problem and its burden in France is not well documented.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The aim of this study was to analyse recent data regarding surgical complications in patients undergoing major digestive cancer surgery, and to estimate its burden for the French society.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p>\n                      Using the 2018 French hospital discharge database and 2017 National CostStudy we studied hospital stays for surgical resection in patients withdigestive cancer. The population was divided into three groups based onpostoperative outcomes: no complications (NC), related infectious complications (RIC) and other complications. The main analysis compared the length and cost per stay between RIC and NC. Forty\u2010Four thousand one hundred and twenty\u2010three stays following a digestive cancer resection were identified. Lower gastro\u2010intestinal cancers were the most prevalent representing 74.8% of stays, the rate of malnutrition was 32.8% and 15.8% of patients presented RIC. Mean (SD) length of stay varied from 11,7 (9.0) days for NC to 25,5\u2009days (19.5) for RIC (p\u2009&lt;\u20090.01). The mean cost per patients' stay (SD) varied from \u20ac10\u2009641 (\u20ac\u20095897) for the NC to \u20ac18\u2009720 (\u20ac7905) for RIC (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The risk of RIC after digestive cancer resection remains high (&gt;15%) and was associated with significantly longer length of stay and higher cost per stay. Although important prevention plans have been implemented in recent years, care strategies are still needed to alleviate the burden on patients and the healthcare system.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cnr2.1895","type":"journal-article","created":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T03:30:10Z","timestamp":1696217410000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Clinical and economic burden of surgical complications during hospitalization for digestive cancer surgery in\n                    <i>France<\/i>"],"prefix":"10.1002","volume":"6","author":[{"given":"Guillaume","family":"Piessen","sequence":"first","affiliation":[{"name":"Service de Chirurgie Digestive et Oncologique CHU Lille  Lille France"},{"name":"CNRS, Inserm, CHU Lille, UMR9020\u2010U1277\u2010CANTHER\u2013Cancer, Heterogeneity Plasticity and Resistance to Therapies University of Lille  Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Dive\u2010Pouletty","sequence":"additional","affiliation":[{"name":"Nestl\u00e9 Health Science  Issy\u2010les Moulineaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aur\u00e9lie","family":"Danel","sequence":"additional","affiliation":[{"name":"Nestl\u00e9 Health Science  Vevey Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magali","family":"Laborey","sequence":"additional","affiliation":[{"name":"Median Conseil  Pau France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5244-6096","authenticated-orcid":false,"given":"Beno\u00eet","family":"Thom\u00e9","sequence":"additional","affiliation":[{"name":"Median Conseil  Pau France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,10,2]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2018.23.46.1800516"},{"key":"e_1_2_11_3_1","unstructured":"Enqu\u00eate nationale de pr\u00e9valence des infections nosocomiales et des traitements anti\u2010infectieux en \u00e9tablissements de sant\u00e9 m\u2010jS\u2010MSpF.2019www.santepubliquefrance.fr"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2004.10.019"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-018-0386-1"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1086\/589331"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-4474-5"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2004.10.017"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2017.219"},{"key":"e_1_2_11_10_1","volume-title":"Healthcare\u2010Associated Infections: Surgical Site Infections.In: ECDC. 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