{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T09:44:36Z","timestamp":1753868676403,"version":"3.41.2"},"reference-count":14,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T00:00:00Z","timestamp":1732060800000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Reports"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Prolonged fever of more than a year duration can be a symptom of underlying malignancy. This article appreciates the need for diligent history taking and carefully performed clinical examination, which is fundamental to reaching an initial diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case<\/jats:title><jats:p>We report the case of a middle\u2010aged male who presented to us with a fever of more than a year duration. The patient's residence was located in a remote area where the nearby tertiary care center was almost 250\u2009km away. He was empirically treated with antibiotics without any success by local physicians. After more than a year, he reported to us and was diagnosed with Hodgkin lymphoma with a characteristic Pel\u2013Ebstein pattern of fever missed earlier by the local physicians. His fever resolved within 5\u2009days of chemotherapy, and he achieved complete remission.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Meticulous history\u2010taking and clinical examination are essential for reaching a clinical diagnosis. Malignant causes should be considered in the differentials of prolonged fever.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cnr2.70039","type":"journal-article","created":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T01:39:23Z","timestamp":1732153163000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hodgkin Lymphoma Presenting as Pel\u2013Ebstein Fever: A Case Report"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-3423-496X","authenticated-orcid":false,"given":"Ujjawal Kumar","family":"Shriwastav","sequence":"first","affiliation":[{"name":"Chitwan Medical College  Bharatpur India"},{"name":"Department of Internal Medicine All India Institute of Medical Sciences  Rishikesh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6378-7694","authenticated-orcid":false,"given":"Deepak","family":"Sundriyal","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Hematology All India Institute of Medical Sciences  Rishikesh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parmod","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Hematology All India Institute of Medical Sciences  Rishikesh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7100-8999","authenticated-orcid":false,"given":"Amit","family":"Sehrawat","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Hematology All India Institute of Medical Sciences  Rishikesh India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,20]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/095952873201700106"},{"key":"e_1_2_10_3_1","article-title":"Professor Pel en \u201cklierkoorts\u201d [Professor Pel and \u201cglandular fever\u201d]","volume":"153","author":"Gijn J.","year":"2009","journal-title":"Nederlands Tijdschrift voor Geneeskunde"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1510093"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/2052-1839-13-9"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3399\/bjgpopen19X101668"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(02)01041-0"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199502163320705"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2009.12.030"},{"key":"e_1_2_10_10_1","first-page":"288","article-title":"Paraneoplastic syndromes","volume":"24","author":"Dinarello C. A.","year":"1997","journal-title":"Fever Seminars in Oncology"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20010915)92:6 <1684::AID-CNCR1497>3.0.CO;2-Z"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-005-0825-4"},{"issue":"2","key":"e_1_2_10_13_1","article-title":"Fever of Unknown Origin: The Workup and Diagnosis of Pel\u2013Ebstein Fever","volume":"14","author":"Khanna P.","year":"2022","journal-title":"Cureus"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)01231-3"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.4103\/2278-330X.130483"}],"container-title":["Cancer Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cnr2.70039","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T03:23:55Z","timestamp":1732677835000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cnr2.70039"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":14,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1002\/cnr2.70039"],"URL":"https:\/\/doi.org\/10.1002\/cnr2.70039","archive":["Portico"],"relation":{},"ISSN":["2573-8348","2573-8348"],"issn-type":[{"type":"print","value":"2573-8348"},{"type":"electronic","value":"2573-8348"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"2024-05-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70039"}}