{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T16:46:28Z","timestamp":1772037988543,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,12,26]],"date-time":"2024-12-26T00:00:00Z","timestamp":1735171200000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Reports"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Screening of rural women of Assam by careHPV test for high\u2010risk HPV (hr\u2010HPV) DNA and Papanicolaou (PAP) test for abnormal cytology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This prospective cross\u2010sectional study included 480 non\u2010pregnant women participants aged 20\u201370\u2009years from Kamrup District, Assam. Two cervical scrap samples were obtained from eligible enrolled women. The Hr\u2010HPV DNA test by CareHPV was performed with one cervical scrap, and a second cervical scrap sample was used for the Papanicolaou (PAP) test. The statistical analysis was done using RStudio for variables. A <jats:italic>p<\/jats:italic>\u2010value &lt;\u20090.05 was considered to be statistically significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Women having positive hr\u2010HPV DNA outcomes were 3.33% (16\/480) and 7.7% (37\/480) women had positive PAP. Tobacco chewing was significantly associated with positive hr\u2010HPV DNA (<jats:italic>p<\/jats:italic>\u2009=\u20090.04) and positive PAP (<jats:italic>p<\/jats:italic>\u2009=\u20090.03) status. Alcohol\u2010consuming women have a significantly higher risk of positive hr\u2010HPV DNA (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.00001) and positive PAP (<jats:italic>p<\/jats:italic>\u20100.04) outcomes. Irregular menstruation (<jats:italic>p<\/jats:italic>\u2009=\u20090.004) and urogenital tract infection (<jats:italic>p<\/jats:italic>\u2009=\u20090.008) also have significant risk for a positive hr\u2010HPV DNA status. The positive hr\u2010HPV DNA status was also significant in women having &gt;\u20093 numbers of children birth (<jats:italic>p<\/jats:italic>\u2009=\u20090.003).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We found that the positive hr\u2010HPV DNA status among rural women in Kamrup, Assam, was significantly associated with alcohol consumption, tobacco chewing, irregular menstruation, urogenital tract infection, and more than three children birth. The abnormal cytology outcome was also substantially associated with tobacco chewing and alcohol consumption.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cnr2.70097","type":"journal-article","created":{"date-parts":[[2024,12,27]],"date-time":"2024-12-27T02:59:21Z","timestamp":1735268361000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["<scp>CareHPV<\/scp>, <scp>Papanicolaou<\/scp> Positivity Status, and Their Association With Behavioral Risk Factors in Rural Women\u00a0of Kamrup District, Assam, India"],"prefix":"10.1002","volume":"7","author":[{"given":"Pallavi","family":"Sarma","sequence":"first","affiliation":[{"name":"DBT Centre for Molecular Biology and Cancer Research Dr B. Borooah Cancer Institute  Guwahati Assam India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debabrata","family":"Barmon","sequence":"additional","affiliation":[{"name":"Department of Gynaecologic Oncology Dr B. Borooah Cancer Institute  Guwahati Assam India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8699-8400","authenticated-orcid":false,"given":"Avdhesh Kumar","family":"Rai","sequence":"additional","affiliation":[{"name":"DBT Centre for Molecular Biology and Cancer Research Dr B. Borooah Cancer Institute  Guwahati Assam India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amal Chandra","family":"Kataki","sequence":"additional","affiliation":[{"name":"Dr B. Borooah Cancer Institute  Guwahati Assam India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anupam","family":"Sarma","sequence":"additional","affiliation":[{"name":"Department of Oncopathology Dr B. Borooah Cancer Institute  Guwahati Assam India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Upasana","family":"Baruah","sequence":"additional","affiliation":[{"name":"Department of Gynaecologic Oncology Dr B. 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