{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T08:50:05Z","timestamp":1790412605173,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:00:00Z","timestamp":1745452800000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Reports"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Metastatic bone disease and pathological fractures in the long bones of the forearm are rare. The methods and outcomes of surgical treatment for these fractures have not been adequately described.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To analyze the outcome of surgery for pathological fractures of the forearm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>Retrospective study of 30 complete and impending pathological fractures (28 consecutive patients) in the forearm, operated on in a single tertiary center between 1986 and 2020. The most common malignancy was hematological disease (multiple myeloma and lymphoma). Most fractures (<jats:italic>n<\/jats:italic>\u2009=\u200919) were managed with plate and screw reconstruction. In some cases, simple curettage or segmental resections of the metastasis were performed. Local complications were noted in six operations, the most common one being tumor relapse seen in three patients. Most patients had good outcomes regarding restoration of function and pain relief. There were no secondary surgeries in segmental resection, and the function was near normal.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Surgical reconstruction of metastases in the long bones of the forearm usually results in a good functional outcome with an acceptable complication rate. Plate osteosynthesis is often indicated. Segmental excision can be reserved for dispensable parts of the ulna and radius, with excellent results.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cnr2.70208","type":"journal-article","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T09:35:26Z","timestamp":1745487326000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Outcome of Surgical Treatment for Metastatic Bone Disease of the Forearm"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2101-747X","authenticated-orcid":false,"given":"Jennifer","family":"Sebghati","sequence":"first","affiliation":[{"name":"Karolinska University Hospital  Solna Sweden"},{"name":"Department of Molecular Medicine and Surgery Karolinska Institute  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6631-2053","authenticated-orcid":false,"given":"Panagiotis","family":"Tsagkozis","sequence":"additional","affiliation":[{"name":"Karolinska University Hospital  Solna Sweden"},{"name":"Department of Molecular Medicine and Surgery Karolinska Institute  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,24]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.3618"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/ctrv.2000.0210"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12893-018-0336-0"},{"issue":"2915","key":"e_1_2_10_5_1","first-page":"2906","article-title":"Acrometastasis: A Literature Review","volume":"19","author":"Stomeo D.","year":"2015","journal-title":"European Review for Medical and Pharmacological Sciences"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-8258(76)90065-2"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11999.0000000000000065"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/CORR.0000000000001036"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbo.2022.100427"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.3109\/17453677908991310"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otsr.2019.07.017"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301\u2010620x.83b4.12202"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.5435\/JAAOS\u2010D\u201023\u201000332"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbo.2021.100352"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo0000093843.72468.3a"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096\u20109098(199703)64:3<>3.0.CO;2\u20105"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.21873\/anticanres.15550"},{"issue":"4","key":"e_1_2_10_18_1","first-page":"1383","article-title":"Surgical Treatment of Pathologic Fractures in Patients With Metastatic Tumors","volume":"33","author":"Zore Z.","year":"2009","journal-title":"Collegium Antropologicum"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199901000-00016"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.suronc.2013.02.008"},{"issue":"1","key":"e_1_2_10_21_1","first-page":"119","article-title":"The IlluminOss System: A Solution in Elderly Patients With Upper Limbs Bone Metastases","volume":"26","author":"Perisano C.","year":"2022","journal-title":"European Review for Medical and Pharmacological Sciences"}],"container-title":["Cancer Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cnr2.70208","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T11:06:21Z","timestamp":1745924781000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cnr2.70208"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1002\/cnr2.70208"],"URL":"https:\/\/doi.org\/10.1002\/cnr2.70208","archive":["Portico"],"relation":{},"ISSN":["2573-8348","2573-8348"],"issn-type":[{"value":"2573-8348","type":"print"},{"value":"2573-8348","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"2024-07-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70208"}}