{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T04:57:30Z","timestamp":1758776250744,"version":"3.44.0"},"reference-count":12,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T00:00:00Z","timestamp":1757376000000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Reports"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To present a case of metastatic endometrial carcinosarcoma (ECS) with a long\u2010term complete response to chemotherapy using a paclitaxel and carboplatin regimen.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Report<\/jats:title><jats:p>A 47\u2010year\u2010old premenopausal woman was diagnosed with a large, advanced intrauterine tumor. She underwent a total abdominal hysterectomy with bilateral salpingo\u2010oophorectomy. Pathological assessment revealed a uterine mass with mesenchymal and epithelial components consistent with ECS, while the right ovarian tumor was identified as serous papillary carcinoma. The patient experienced a prolonged postoperative recovery period lasting 3\u2009months. Staging workup later revealed recurrence of adnexal and pulmonary lesions, indicating metastasis. The patient received 6\u2009cycles of postoperative chemotherapy consisting of paclitaxel and carboplatin, achieving complete remission that has persisted for 3\u2009years since the initial diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This case highlights the efficacy of postoperative chemotherapy using paclitaxel and carboplatin in the successful treatment of metastatic ECS.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cnr2.70346","type":"journal-article","created":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T07:59:11Z","timestamp":1757404751000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Long\u2010Term Complete Remission of Metastatic Endometrial Carcinosarcoma With Radical Surgical Resection and Postoperative Chemotherapy Utilizing Paclitaxel and Carboplatin"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7524-5887","authenticated-orcid":false,"given":"Kambiz","family":"Novin","sequence":"first","affiliation":[{"name":"Radiation Oncology Department, School of Medicine Iran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3931-5395","authenticated-orcid":false,"given":"Soroush","family":"Shahrokh","sequence":"additional","affiliation":[{"name":"Texas Tech University Health Sciences Center  Lubbock Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3462-894X","authenticated-orcid":false,"given":"Mohadese","family":"Shahin","sequence":"additional","affiliation":[{"name":"Radiation Oncology Department, School of Medicine Iran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6195-2203","authenticated-orcid":false,"given":"Farzad","family":"Taghizadeh\u2010Hesary","sequence":"additional","affiliation":[{"name":"ENT and Head and Neck Research Center and Department, the Five Senses Health Institute, School of Medicine Iran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,9]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_12_2_1","DOI":"10.1097\/GRF.0b013e31821ac635"},{"doi-asserted-by":"publisher","key":"e_1_2_12_3_1","DOI":"10.7759\/cureus.10283"},{"doi-asserted-by":"publisher","key":"e_1_2_12_4_1","DOI":"10.1136\/ijgc\u20102022\u2010004073"},{"doi-asserted-by":"publisher","key":"e_1_2_12_5_1","DOI":"10.1017\/9781108935579.075"},{"doi-asserted-by":"publisher","key":"e_1_2_12_6_1","DOI":"10.1080\/13697137.2024.2376189"},{"doi-asserted-by":"publisher","key":"e_1_2_12_7_1","DOI":"10.1016\/j.critrevonc.2007.06.011"},{"doi-asserted-by":"publisher","key":"e_1_2_12_8_1","DOI":"10.1038\/s41467\u2010019\u201012985\u2010x"},{"doi-asserted-by":"publisher","key":"e_1_2_12_9_1","DOI":"10.1186\/s13244\u2010021\u201001084\u20105"},{"doi-asserted-by":"publisher","key":"e_1_2_12_10_1","DOI":"10.1007\/s00404\u2010012\u20102529\u20106"},{"key":"e_1_2_12_11_1","article-title":"Adjuvant Radiotherapy and\/or Chemotherapy After Surgery for Uterine Carcinosarcoma","volume":"1","author":"Galaal K.","year":"2011","journal-title":"Cochrane Database of Systematic Reviews"},{"doi-asserted-by":"publisher","key":"e_1_2_12_12_1","DOI":"10.1136\/ijgc\u20102020\u2010001315"},{"doi-asserted-by":"publisher","key":"e_1_2_12_13_1","DOI":"10.1200\/JCO.2006.06.4907"}],"container-title":["Cancer Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cnr2.70346","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T04:07:26Z","timestamp":1758773246000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cnr2.70346"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":12,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1002\/cnr2.70346"],"URL":"https:\/\/doi.org\/10.1002\/cnr2.70346","archive":["Portico"],"relation":{},"ISSN":["2573-8348","2573-8348"],"issn-type":[{"type":"print","value":"2573-8348"},{"type":"electronic","value":"2573-8348"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"2024-11-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70346"}}