{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T07:39:00Z","timestamp":1764056340154,"version":"3.45.0"},"reference-count":12,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:00:00Z","timestamp":1761696000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Reports"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Breast cancer in males is rare, accounting for just 0.5% to 1% according to World Health Organization data. This is the first reported case of IESCM from breast cancer in an African male, which makes it noteworthy. Furthermore, unlike previously reported cases in females, this case involved L1\u2013L2 metastasis with sphincter dysfunction and a subsequent relapse leading to mortality, thereby expanding the documented spectrum of IESCM presentations and outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>This is a case of a 77\u2010year\u2010old male with invasive ductal carcinoma of the left breast and intradural extramedullary spinal cord metastasis diagnosed via Magnetic Resonance Imaging after presenting with neurological symptoms 4\u2009years post\u2010mastectomy. He eventually passed away following a right Deep Venous Thrombosis, which led to bilateral pulmonary embolism after his second relapse.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Late presentation most likely contributed to the worsening of symptoms and poor prognosis. This report overstates the importance of prompt access to healthcare and the essence of thorough investigations, especially in breast cancer, where neurological symptoms may point to a metastatic diagnosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cnr2.70382","type":"journal-article","created":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T04:22:11Z","timestamp":1761798131000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Intradural Extramedullary Spinal Cord Metastasis of Breast Cancer in a Male: A Case Report"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-8248-9227","authenticated-orcid":false,"given":"Hadi Mohammed","family":"Abdullah","sequence":"first","affiliation":[{"name":"Department of Neurosurgery Korle\u2010Bu Teaching Hospital  Accra Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1685-5287","authenticated-orcid":false,"given":"Naa Adzoa Adzeley","family":"Boi\u2010Dsane","sequence":"additional","affiliation":[{"name":"Department of Epidemiology The Noguchi Memorial Institute for Medical Research, University of Ghana  Accra Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1723-7730","authenticated-orcid":false,"given":"George","family":"Wepeba","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Korle\u2010Bu Teaching Hospital  Accra Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5041-324X","authenticated-orcid":false,"given":"Thomas","family":"Dakurah","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Korle\u2010Bu Teaching Hospital  Accra Ghana"},{"name":"Department of Surgery University of Ghana Medical School  Accra Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,29]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"World Health Organization Breast Cancer Caused 670 000 Deaths Globally in 2022 Roughly Half of All Breast Cancers Occur in Women With No Specific Risk Factors Other Than Sex and Age Breast Cancer Was the Most Common Cancer in Women in 157 Countries Out of 185 in 2022 Breast Cancer Occurs in Every Country in the World Approximately 0.5\u20131% of Breast Cancers Occur in Men. Breast Cancer 2024 https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/breast\u2010cancer."},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.4314\/jmbs.v3i3.4"},{"volume-title":"StatPearls [Internet]","year":"2025","author":"Ziu E.","key":"e_1_2_9_4_1"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199208273270907"},{"volume-title":"Centres for Disease Control and Prevention. Male Breast Cancer Incidence and Mortality, United States\u20142013\u20132017","year":"2020","author":"U.S. Cancer Statistics Data Briefs, No. 19","key":"e_1_2_9_6_1"},{"issue":"1","key":"e_1_2_9_7_1","first-page":"140","article-title":"Male Breast Cancer: A Review","volume":"3","author":"Fentiman I. S.","year":"2009","journal-title":"Ecancermedicalscience"},{"key":"e_1_2_9_8_1","first-page":"337","volume-title":"Breast Disease: Management and Therapies: Volume 2","author":"Igci A.","year":"2022"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000136825"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.21873\/anticanres.16189"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0042-1750806"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-031-16199-5_73"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.21873\/anticanres.15814"}],"container-title":["Cancer Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cnr2.70382","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T07:36:47Z","timestamp":1764056207000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cnr2.70382"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,29]]},"references-count":12,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1002\/cnr2.70382"],"URL":"https:\/\/doi.org\/10.1002\/cnr2.70382","archive":["Portico"],"relation":{},"ISSN":["2573-8348","2573-8348"],"issn-type":[{"type":"print","value":"2573-8348"},{"type":"electronic","value":"2573-8348"}],"subject":[],"published":{"date-parts":[[2025,10,29]]},"assertion":[{"value":"2024-08-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70382"}}