{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T11:24:12Z","timestamp":1767007452000,"version":"3.45.0"},"reference-count":32,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T00:00:00Z","timestamp":1762300800000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Reports"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>Existing literature on ovarian masses necessitating intervention in children by pediatric surgeons and gynecologists in Low\u2010 and Middle\u2010Income Countries is sparse and lacks collaborative standardization in management between the two subspecialties. Therefore, this study seeks to assess the range of ovarian masses presenting to these two specialties and to explore variations in management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A 15\u2010year retrospective review of surgically biopsied or excised ovarian masses between subspecialties at two academic hospitals in Johannesburg.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We identified 288 patients, six with bilateral disease and 294 ovarian masses. The mean age was 13.34\u2009years (SD \u00b15.12). The most common presentation was abdominal pain in 149\/288 (51.74%); 117 patients (40.62%) were from pediatric surgery and 171 (59.38%) from gynecology departments. There were 127\/288 (44.09%) non\u2010neoplastic and 161\/288 (55.90%) neoplastic lesions, of which 110\/161 (68.33%) were benign and 51\/161 (31.67%) malignant. The neoplastic lesions consisted of 107\/161 (66.45%) germ cells, 28\/161 (17.39%) surface epithelial tumors, and 26\/161 (16.14%) sex cord\u2010stromal tumors. Ovarian\u2010sparing surgery was done in 56\/288 (19.44%) patients, 22\/117 (18.80%) in pediatric surgery, and 34\/171 (19.88%) in gynecology. Laparoscopy was done in 57\/288 (19.79%) patients, 24\/117 (20.51%) in pediatric surgery, and 19\/171 (19.29%) in gynecology. The survival rate in benign masses was 100%, and 86.28% in malignancies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study highlights the diverse spectrum of ovarian masses managed by pediatric surgeons and gynecologists. A laparoscopic approach combined with ovarian preservation, which was comparable between specialties, should be the preferred method for managing benign lesions whenever feasible. These findings underscore the need for standardized, collaborative guidelines between pediatric surgeons and gynecologists to ensure consistent and optimal management of ovarian masses in children.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cnr2.70396","type":"journal-article","created":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T10:06:06Z","timestamp":1762337166000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Surgical Management of Ovarian Masses in Children: A Comparative Analysis by Pediatric Surgeons and Gynecologists at Two Academic Hospitals in Johannesburg"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-2911-4211","authenticated-orcid":false,"given":"Nkhensani C.","family":"Mashaba","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery, School of Clinical Medicine, Faculty of Health Sciences University of the Witwatersrand  Johannesburg South Africa"},{"name":"Department of Pediatric Surgery Polokwane\u2010Mankweng Tertiary and Academic Hospital, University of Limpopo  Polokwane South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5950-791X","authenticated-orcid":false,"given":"Langanani","family":"Mbodi","sequence":"additional","affiliation":[{"name":"Department of Gynecologic Oncology, School of Clinical Medicine, Faculty of Health Sciences University of the Witwatersrand  Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0291-6001","authenticated-orcid":false,"given":"Ellen M.","family":"Mapunda","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, School of Clinical Medicine, Faculty of Health Sciences University of the Witwatersrand  Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7636-7616","authenticated-orcid":false,"given":"Tanvier","family":"Omar","sequence":"additional","affiliation":[{"name":"Division of Anatomical Pathology, School of Pathology, Faculty of Health Sciences University of the Witwatersrand  Johannesburg South\u00a0Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7093-1383","authenticated-orcid":false,"given":"Derek S.","family":"Harrison","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, School of Clinical Medicine, Faculty of Health Sciences University of the Witwatersrand  Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,5]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2019.10.032"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.4102\/sajo.v3i0.87"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.7196\/SAMJ.2015.v105i11.9780"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpag.2013.07.007"},{"key":"e_1_2_10_6_1","first-page":"529","volume-title":"Pediatric Surgery: Expert Consult\u2010Online and Print","author":"Coran A. 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