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Measurable combined inflammatory markers in the blood, which indicate the inflammatory response, play a crucial role in managing patients with malignancies. These markers have been validated as less invasive, practical, and cost\u2010effective tools in the clinical decision\u2010making process. The aim of this study is to evaluate the predictive value of inflammatory markers based on complete blood count (CBC), including neutrophil\u2010to\u2010lymphocyte ratio (NLR), platelet\u2010to\u2010lymphocyte ratio (PLR), and lymphocyte\u2010to\u2010monocyte ratio (LMR) in major solid tumors, including breast, lung, colorectal, and prostate cancers, due to their high prevalence and strong evidence base.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Recent Findings<\/jats:title>\n                    <jats:p>In this study, studies from 2015 to June 2025 were searched in Google Scholar, PubMed, and Scopus using keywords such as neutrophil\u2010to\u2010lymphocyte ratio, platelet\u2010to\u2010lymphocyte ratio, monocyte\u2010to\u2010lymphocyte ratio, prognosis value, predictive value, diagnosis value, lung cancer, colon cancer, prostate cancer, and breast cancer. Findings indicate that elevated NLR and PLR, alongside reduced LMR, are commonly associated with advanced disease, poorer survival, and diminished response to treatment, though the strength of evidence varies by cancer type. Limitations across studies include retrospective design, inconsistent cut\u2010off values, and confounding factors such as comorbidities and treatment regimens.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Current evidence suggests that NLR, PLR, and LMR have significant potential as accessible biomarkers for risk stratification and treatment monitoring in common solid tumors. However, lack of standardization in methodology and cut\u2010off definitions limits their widespread clinical implementation. High\u2010quality prospective studies are needed to establish unified thresholds and clarify their role alongside established biomarkers.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cnr2.70407","type":"journal-article","created":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T10:40:39Z","timestamp":1764240039000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["The Evaluation of Diagnostic, Prognostic, and Predictive Role of Hematologic Inflammatory Indices\n                    <scp>NLR<\/scp>\n                    ,\n                    <scp>PLR<\/scp>\n                    , and\n                    <scp>LMR<\/scp>\n                    in Common Solid Tumors"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-9629-4443","authenticated-orcid":false,"given":"Fatemeh","family":"Arianmanesh","sequence":"first","affiliation":[{"name":"Department of Hematology and 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