{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T17:12:27Z","timestamp":1766509947566,"version":"3.48.0"},"reference-count":26,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T00:00:00Z","timestamp":1765324800000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Reports"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Radiofrequency ablation (RFA) can be an alternative management method for patients who are not candidates for surgery or who refuse it. There are limited data concerning the role of RFA in patients with medullary thyroid carcinoma (MTC). This case is presented to discuss the efficacy of RFA in the management of nonmetastatic MTC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case<\/jats:title>\n                    <jats:p>In this report, we present the case of an 83\u2010year\u2010old male with MTC who refused thyroidectomy. RFA was performed and he was followed for 1\u2009year. In this case, RFA resulted in significant reductions in tumor size and calcitonin levels without any significant complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This research indicates that Radiofrequency Ablation (RFA) can yield acceptable results in the management of Medullary Thyroid Cancer (MTC). However, ongoing investigation remains crucial to clarify long\u2010term outcomes and to compare RFA's efficacy against conventional management methods.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cnr2.70419","type":"journal-article","created":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T14:18:35Z","timestamp":1765376315000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Efficacy of Radiofrequency Ablation in Treating Nonmetastatic Medullary Thyroid Carcinoma: A Case Study"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1037-4463","authenticated-orcid":false,"given":"Hojat","family":"Ebrahiminik","sequence":"first","affiliation":[{"name":"Department of Interventional Radiology and Radiation Sciences Research Center AJA University of Medical Sciences  Tehran 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