{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T23:27:07Z","timestamp":1769556427657,"version":"3.49.0"},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,4]],"date-time":"2026-01-04T00:00:00Z","timestamp":1767484800000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Reports"],"published-print":{"date-parts":[[2026,1]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n Maxillofacial squamous cell carcinoma (SCC) typically metastasizes to lymph nodes, yet coexisting tuberculous lymphadenitis is extraordinarily rare, posing diagnostic challenges.<\/jats:p>\n <\/jats:sec>\n \n Case<\/jats:title>\n A 68\u2010year\u2010old female with right maxillofacial SCC and ipsilateral lymphadenopathy underwent radical resection and selective neck dissection after computed tomography had shown nodes with central necrosis and rim enhancement\u2014features indeterminate for metastasis versus infection. Histopathological examination of the dissected lymph nodes revealed concurrent metastatic SCC foci and tuberculous granulomas. Further tuberculosis\u2010specific tests returned positive results, confirming the final diagnosis of metastatic maxillofacial SCC with coexisting tuberculous lymphadenitis. Notably, the patient had no tuberculosis\u2010related symptoms, with tuberculous lymphadenitis unsuspected preoperatively, underscoring the diagnostic challenge of such coexisting conditions.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n This case highlights the importance of considering infectious comorbidities, particularly in cases with atypical imaging or clinical manifestations, when evaluating lymph node lesions in cancer patients to avoid misdiagnosis and optimize therapeutic strategies.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/cnr2.70454","type":"journal-article","created":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T05:41:42Z","timestamp":1767591702000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Maxillofacial Squamous Cell Carcinoma With Cervical Metastasis and Tuberculous Lymphadenitis: Diagnostic Dilemmas and Clinical Insights"],"prefix":"10.1002","volume":"9","author":[{"given":"Xierzhati","family":"Tuerxun","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Kashi Prefecture Second People's Hospital Kashi Xinjiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-9904-6774","authenticated-orcid":false,"given":"Meiheriban","family":"Tuerhong","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Kashi Prefecture Second People's Hospital Kashi Xinjiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-8721-818X","authenticated-orcid":false,"given":"Zainure","family":"Wubulihasimu","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Kashi Prefecture Second People's Hospital Kashi Xinjiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9259-0496","authenticated-orcid":false,"given":"Baihetiyaer","family":"Yimin","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Kashi Prefecture Second People's Hospital Kashi Xinjiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0505-0993","authenticated-orcid":false,"given":"Maimaitituxun","family":"Tuerdi","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Trauma and Orthognathic Surgery The First Affiliated Hospital of Xinjiang Medical University Urumqi Xinjiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6578-8132","authenticated-orcid":false,"given":"Kai","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Kashi Prefecture Second People's Hospital Kashi Xinjiang China"},{"name":"Department of Oral and Craniomaxillofacial Surgery, Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine Shanghai China"},{"name":"College of Stomatology Shanghai Jiao Tong University Shanghai China"},{"name":"National Center for Stomatology Shanghai China"},{"name":"National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,4]]},"reference":[{"issue":"7","key":"e_1_2_15_2_1","article-title":"Review of Head and Neck Masses in the Indian Population Based on Prevalence and Etiology With an Emphasis on Primary Diagnostic Modalities","volume":"13","author":"Bhasker N.","year":"2021","journal-title":"Cureus"},{"issue":"10","key":"e_1_2_15_3_1","article-title":"Delayed Diagnosis of Inborn Errors of Immunity due to CISH Gene Mutation Presenting as Recurrent Tuberculosis","volume":"16","author":"Munshi A.","year":"2024","journal-title":"Cureus"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-020-02075-6"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2025.1561719"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijtb.2023.09.006"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmcr.2021.101485"},{"issue":"5","key":"e_1_2_15_8_1","article-title":"The Role of Surgery in the Treatment of Cervical Lymph Node Tuberculosis","volume":"15","author":"Tahiri I.","year":"2023","journal-title":"Cureus"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-024-04913-9"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/tcmj.tcmj_86_22"}],"container-title":["Cancer Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cnr2.70454","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cnr2.70454","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cnr2.70454","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T10:11:41Z","timestamp":1769508701000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cnr2.70454"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1002\/cnr2.70454"],"URL":"https:\/\/doi.org\/10.1002\/cnr2.70454","archive":["Portico"],"relation":{},"ISSN":["2573-8348","2573-8348"],"issn-type":[{"value":"2573-8348","type":"print"},{"value":"2573-8348","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-06-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70454"}}