{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T19:40:49Z","timestamp":1786390849111,"version":"build-2736575974"},"reference-count":33,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Reports"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Kaposi sarcoma herpes virus (KSHV) is associated with multiple clinical manifestations, including primary effusion lymphoma, an aggressive CD38+ B cell lymphoma with a plasmablastic phenotype.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case<\/jats:title>\n                    <jats:p>This case describes an antiretroviral therapy\u2010adherent person with HIV who presented with concurrent KSHV\u2010related disorders of Kaposi sarcoma (KS), multicentric Castleman disease (MCD), and extracavitary primary effusion lymphoma (EC\u2010PEL). Single\u2010cell RNAseq (scRNAseq) and multiplex immunohistochemistry (mIHC) provide detailed insights into differences in cellular composition and viral and cellular transcriptomic differences between these diseases. Moreover, the case describes a long\u2010term remission with single\u2010agent anti\u2010CD38 antibody, daratumumab, in a chemotherapy\u2010refractory case.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This case highlights the differing clinical manifestations of KSHV and the efficacy of immunotherapy in KSHV\u2010associated primary effusion lymphoma.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cnr2.70589","type":"journal-article","created":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T22:40:11Z","timestamp":1780353611000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Synchronous Manifestations of Kaposi Sarcoma Herpesvirus\u2010Associated Disorders"],"prefix":"10.1002","volume":"9","author":[{"given":"Kandice","family":"Roberts","sequence":"first","affiliation":[{"name":"Department of Medicine Washington University in St Louis School of Medicine  St Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Vali\u00f1o Ramos","sequence":"additional","affiliation":[{"name":"Department of Microbiology Washington University in St Louis School of Medicine  St Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saurabh","family":"Jindal","sequence":"additional","affiliation":[{"name":"Department of Radiology Washington University in St Louis School of Medicine  St Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikas","family":"Prasad","sequence":"additional","affiliation":[{"name":"Department of Radiology Washington University in St Louis School of Medicine  St Louis Missouri 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University in St Louis School of Medicine  St Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Simonson","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology University of Washington  Seatle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Odeny","sequence":"additional","affiliation":[{"name":"Department of Medicine Washington University in St Louis School of Medicine  St Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2744-7294","authenticated-orcid":false,"given":"Lee","family":"Ratner","sequence":"additional","affiliation":[{"name":"Department of Medicine Washington University in St Louis School of Medicine  St Louis Missouri USA"},{"name":"Department of Microbiology Washington University in St Louis School of Medicine  St Louis Missouri 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