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A search on Medline, African Journals Online, Web of Science, and Embase was performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Recent Findings<\/jats:title>\n                    <jats:p>Distribution of molecular subtypes, such as Luminal A or B, HER2\u2010enriched and Triple\u2010negative, was also analyzed. From 125 selected studies comprising 42689 patients with staged breast cancer, 63.1% were diagnosed at a late stage, with regional variations (74.5% in Middle Africa, 68.5% in Eastern Africa, 71% in Western Africa, and 55.2% in Southern Africa).Luminal subtypes (A and B) accounted for 68.2% of cases, followed by triple\u2010negative breast cancer (21.1%) and HER2\u2010enriched tumors (10.6%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our findings provide an updated synthesis of the stage at diagnosis of breast cancer in sub\u2010Saharan Africa since January 2014. Although a high proportion of patients continue to present at late stage, comparisons with earlier reports should be interpreted cautiously due to heterogeneity in study populations, regional representation, and reporting practices. These findings should be interpreted as an updated regional synthesis rather than evidence of a confirmed temporal improvement in stage at diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>The review protocol was not registered in PROSPERO which we acknowledge as a limitation<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cnr2.70594","type":"journal-article","created":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T07:59:23Z","timestamp":1781078363000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Stage at Diagnosis and Molecular Subtype Distribution of Breast Cancer in Sub\u2010Saharan Africa: A Systematic Review"],"prefix":"10.1002","volume":"9","author":[{"given":"A\u00efssatou Dada","family":"Fall","sequence":"first","affiliation":[{"name":"Department of Medicine and Surgery Universidad CEU Cardenal Herrera, CEU Universities  Alfara del Patriarca Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0063-0830","authenticated-orcid":false,"given":"Veronica","family":"Veses","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences Universidad CEU Cardenal Herrera, CEU Universities  Alfara del Patriarca Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8303-0218","authenticated-orcid":false,"given":"Chirag C.","family":"Sheth","sequence":"additional","affiliation":[{"name":"Department of Medicine and Surgery Universidad CEU Cardenal Herrera, CEU Universities  Alfara del Patriarca Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,10]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21834"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2022.08.010"},{"key":"e_1_2_10_4_1","unstructured":"J.Ferlay M.Laversanne M.Ervik et\u00a0al. \u201cGlobal Cancer Observatory: Cancer Tomorrow (Version 1.1). 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