{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T10:11:25Z","timestamp":1780913485604,"version":"3.54.1"},"reference-count":50,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T00:00:00Z","timestamp":1775779200000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100012547","name":"Natural Science Foundation of Guangxi Zhuang Autonomous Region","doi-asserted-by":"publisher","award":["2025GXNSFAA069038"],"award-info":[{"award-number":["2025GXNSFAA069038"]}],"id":[{"id":"10.13039\/100012547","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82260243;82560240."],"award-info":[{"award-number":["82260243;82560240."]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["CNS Neurosci Ther"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate whether dynamic changes in resting\u2010state functional MRI (rs\u2010fMRI) metrics can serve as sensitive biomarkers for distinguishing acute basal ganglia cerebral infarction (BGCI) patients with post\u2010stroke cognitive impairment (PSCI) from those without (non\u2010PSCI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Data on various rs\u2010fMRI metrics dynamic functional connectivity (dFC), dynamic amplitude of low\u2010frequency fluctuation (dALFF), and percent amplitude of fluctuation (PerAF) were acquired using a Siemens Prisma 3.0T scanner from 38 PSCI and 36 non\u2010PSCI patients, with follow\u2010up assessments. Functional segregation and integration were analyzed using PerAF, dALFF, and dFC. Feature extraction and selection were performed using support vector machine (SVM), followed by classifier construction and evaluation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Patients with PSCI showed decreased PerAF in the left cerebellar Crus I (lCbeCru1) and increased dALFF in the right cerebellar Crus I and left lingual gyrus compared to non\u2010PSCI patients. Altered dFC was observed between cerebellar cognitive\u2010related seed regions and widespread cortical areas, with increased dFC in the right cerebellar Crus II and left cuneus, and decreased dFC primarily in the inferior frontal gyrus and superior temporal gyrus. Among single\u2010feature models, dFC achieved the best classification performance (AUC\u2009=\u20090.98, accuracy\u2009=\u200994.52%, sensitivity\u2009=\u200997.14%, specificity\u2009=\u200992.11%, precision\u2009=\u200991.89%). A combined feature model yielded the highest precision (94.12%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>SVM\u2010based integration of PerAF, dALFF, and dFC features holds promise as a neuroimaging biomarker for PSCI in patients with BGCI. This approach may support more precise early rehabilitation strategies in clinical practice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cns.70871","type":"journal-article","created":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T16:00:30Z","timestamp":1775836830000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Decoding Post\u2010Stroke Cognitive Impairment After Acute Basal Ganglia Infarction: The Synergistic Role of Functional Segregation and Integration in an\n                    <scp>SVM fMRI<\/scp>\n                    Framework"],"prefix":"10.1002","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6547-3608","authenticated-orcid":false,"given":"Shijian","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Neurology The First Affiliated Hospital of Guangxi Medical University  Nanning Guangxi China"},{"name":"Department of Neurology The Fourth Affiliated 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