{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T07:19:32Z","timestamp":1787901572227,"version":"build-2784847793"},"reference-count":31,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T00:00:00Z","timestamp":1785801600000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004733","name":"Universidade de Macau","doi-asserted-by":"publisher","award":["UMDF\u2010TISF\u2010I\/2026\/019\/ICMS"],"award-info":[{"award-number":["UMDF\u2010TISF\u2010I\/2026\/019\/ICMS"]}],"id":[{"id":"10.13039\/501100004733","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004733","name":"Universidade de Macau","doi-asserted-by":"publisher","award":["SRG2025\u201000027\u2010ICMS"],"award-info":[{"award-number":["SRG2025\u201000027\u2010ICMS"]}],"id":[{"id":"10.13039\/501100004733","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["CNS Neurosci Ther"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Stroke incidence and mortality are higher among adults in northern and western China, commonly referred to as the \u201cStroke Belt.\u201d However, few studies have compared stroke action awareness between Stroke Belt and non\u2013Stroke Belt regions at the national level. This study aimed to evaluate stroke action awareness\u2014including recognition of symptoms and appropriate emergency responses\u2014among community residents in China, with comparisons between Stroke Belt and non\u2010Stroke Belt regions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a cross\u2010sectional, questionnaire\u2010based survey of community residents across China to assess knowledge of stroke symptoms and appropriate responses to suspected stroke events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 6181 residents were included in the final analysis, with 2037 living in Stroke Belt regions and 4144 in non\u2010Stroke Belt regions. Overall, 19.07% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20091179) were unaware of any stroke symptoms, 17.96% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20091110) recognized one symptom, 11.97% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009740) recognized two symptoms, and 50.99% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20093152) recognized all three. Additionally, 77.59% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20094796) identified calling emergency medical services (EMS) as the correct response. Multivariable logistic regression showed that residents of the Stroke Belt had significantly lower odds of recognizing all three symptoms (adjusted odds ratio [aOR]: 0.50; 95% CI: 0.44\u20130.56;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), calling EMS (aOR: 0.62; 95% CI: 0.54\u20130.70;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and both recognizing all three symptoms and calling EMS (aOR: 0.51; 95% CI: 0.45\u20130.58;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Stroke action awareness remains notably low among community residents in China, with the lowest levels observed in the Stroke Belt. Targeted public health interventions are urgently needed to improve symptom recognition and promote timely action for emergency stroke care, especially in high\u2010risk regions such as the Stroke Belt.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cns.71056","type":"journal-article","created":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T09:48:18Z","timestamp":1785836898000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Geographic Disparities in Stroke Action Awareness in China: A National Survey"],"prefix":"10.1002","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0906-1822","authenticated-orcid":false,"given":"Jing","family":"Yuan","sequence":"first","affiliation":[{"name":"Institute of Chinese Medical Sciences, Centre for Pharmaceutical Regulatory Sciences &amp; Faculty of Health Sciences University of Macau  Macao SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renyu","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care Perelman School of Medicine at the University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-7437-5162","authenticated-orcid":false,"given":"Yu","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Neurology Affiliated Hospital of Xuzhou Medical University  Xuzhou Jingsu Province People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurology Sixian People's Hospital  Suzhou Anhui Province People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shujian","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurology Fangcheng County People's Hospital  Nanyang Henan Province People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Neurology People's Hospital of Xinjiang Uygur Autonomous Region  Urumqi People's Republic of China"},{"name":"Xinjiang Clinical Research Center for Stroke and Neurological Rare Disease  Urumqi People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0293-2744","authenticated-orcid":false,"given":"Xunming","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Xuanwu Hospital, Capital Medical University  Beijing People's Republic of China"},{"name":"Beijing Key Laboratory of Hypoxic Conditioning Translational Medicine Xuanwu Hospital, Capital Medical University  People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Neurology Minhang Hospital, Fudan University  Shanghai 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