{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T21:03:05Z","timestamp":1791406985568,"version":"4.3.3"},"reference-count":51,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T00:00:00Z","timestamp":1787356800000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["CNS Neurosci Ther"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Spinal cord stimulation (SCS) is a promising treatment for disorders of consciousness (DoC), but early neurophysiological markers of durable recovery remain unclear. We aimed to determine whether source\u2010space EEG network energy and communication features capture early brain\u2010network reorganization linked to 6\u2010month recovery in chronic DoC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Thirty\u2010one chronic DoC patients undergoing cervical SCS completed resting\u2010state EEG before stimulation and at 1\u2009week and 1\u2009month after stimulation onset. Source\u2010space EEG was analyzed across delta, theta, alpha, and beta bands. NetPower quantified network energy within five canonical networks, and ModularAUC quantified threshold\u2010robust within\u2010 and between\u2010network communication. EEG features were related to 6\u2010month CRS\u2010R outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Recovery was associated with sustained alpha\/beta NetPower enhancement across default mode, frontoparietal, cingulo\u2010opercular, somatomotor, and occipital networks, peaking at 1\u2009month. Beta\u2010band ModularAUC showed the clearest communication\u2010architecture consolidation, with broader within\u2010 and cross\u2010network synergy in recovered patients. Low\u2010frequency changes were weaker and less consistent. High\u2010frequency NetPower features, especially FPN alpha at 1\u2009month and CON beta at 1\u2009week, showed the strongest associations with long\u2010term improvement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>SCS\u2010related recovery in DoC is characterized by high\u2010frequency network\u2010energy enhancement and beta\u2010band communication consolidation. Here, high\u2010frequency network reorganization mainly refers to alpha\u2010 and beta\u2010band source\u2010space EEG changes. Source\u2010space EEG may provide early potential neurophysiological markers for monitoring recovery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cns.71101","type":"journal-article","created":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T08:07:32Z","timestamp":1787386052000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Early High\u2010Frequency Network Reorganization After Spinal Cord Stimulation Is Linked to Long\u2010Term Recovery in Disorders of Consciousness"],"prefix":"10.1002","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-9813-7895","authenticated-orcid":false,"given":"Kang","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Neurosurgery The First Hospital of Jilin University  Changchun 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