{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T07:10:10Z","timestamp":1750144210896,"version":"3.41.0"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T00:00:00Z","timestamp":1749513600000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Annals of the Child Neurology Society"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Fenfluramine is an antiseizure medication approved by the Food and Drug Administration\u00a0for the treatment of Dravet syndrome in patients older than 2 years. Fenfluramine is an amphetamine derivative. It cross\u2010reacts with amphetamines in urine drug screen immunoassays.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patient Presentation<\/jats:title><jats:p>A 2\u2010year\u2010old patient with Dravet syndrome had\u00a0a cardiorespiratory arrest and tested positive for amphetamines in a urine drug screen, raising concerns of child abuse. Liquid chromatography\u2013mass spectrometry confirmed the presence of fenfluramine but did not detect amphetamines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Fenfluramine can result in a false\u2010positive amphetamine urine drug screen at the recommended dose for Dravet syndrome. Awareness of this potential cross\u2010reactivity can prevent undue child protective services reports, especially in patients at high risk for sudden death.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cns3.70012","type":"journal-article","created":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T14:13:18Z","timestamp":1749564798000},"page":"121-124","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Fenfluramine: An Uncommon Cause of False Positive Urine Drug Testing: A Case Report"],"prefix":"10.1002","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-3108-5701","authenticated-orcid":false,"given":"Maria","family":"Ghawji","sequence":"first","affiliation":[{"name":"Children's Medical Center Dallas Texas USA"},{"name":"University of Texas Southwestern Medical Center Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meagan","family":"Hainlen","sequence":"additional","affiliation":[{"name":"Children's Medical Center Dallas Texas USA"},{"name":"University of Texas Southwestern Medical Center Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charuta","family":"Joshi","sequence":"additional","affiliation":[{"name":"Children's Medical Center Dallas Texas USA"},{"name":"University of Texas Southwestern Medical Center Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2016.09.007"},{"key":"e_1_2_7_3_1","unstructured":"International League Against Epilepsy \"Dravet Syndrome (DS) \" EpilepsyDiagnosis.org accessed May 28 2025 https:\/\/www.epilepsydiagnosis.org\/syndrome\/dravet-overview.html."},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2023.1192022"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-023-01881-w"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40120-023-00452-1"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.17866"},{"key":"e_1_2_7_8_1","unstructured":"\u201cData Analysis Dashboard \u201d WebPOISONCONTRO accessed May 28 2025 https:\/\/www.poison.org\/webpoisoncontrol-data-analysis-dashboard#Age%20Distribution."},{"issue":"4","key":"e_1_2_7_9_1","first-page":"305","article-title":"[The Urinary Screening and Identification of Amphetamines in Clinical Toxicology Laboratory\u2014VGH]","volume":"48","author":"Lin W. 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