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Protonation equilibria in dilute dichloromethane solution of a shape\u2010persistent macrocycle bearing two 2,2\u2032\u2010bipyridine units and two Coumarin 2 moieties (see figure) can be exploited to mimic decoding operations.<jats:boxed-text content-type=\"graphic\" position=\"anchor\"><jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/gif\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/mcontent.gif\"><jats:alt-text>magnified image<\/jats:alt-text><\/jats:graphic><\/jats:boxed-text><\/jats:p>","DOI":"10.1002\/cphc.200800793","type":"journal-article","created":{"date-parts":[[2009,1,13]],"date-time":"2009-01-13T08:34:49Z","timestamp":1231835689000},"page":"495-498","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["A Chemical System that Mimics Decoding Operations"],"prefix":"10.1002","volume":"10","author":[{"given":"Carlo","family":"Giansante","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Ceroni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margherita","family":"Venturi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junji","family":"Sakamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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