{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T23:31:12Z","timestamp":1790897472604,"version":"4.1.0"},"reference-count":54,"publisher":"Wiley","issue":"22","license":[{"start":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T00:00:00Z","timestamp":1695772800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ChemPhysChem"],"published-print":{"date-parts":[[2023,11,16]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>As an exceptional Fenton\u2010like reagent, cerium oxide (CeO<jats:sub>2<\/jats:sub>) finds applications in biomedical science and organic pollutants treatment. The Fenton\u2010like reaction catalyzed by CeO<jats:sub>2<\/jats:sub> typically encompasses two distinct processes: one resembling the classical Fenton reaction, wherein cerium (Ce<jats:sup>3+<\/jats:sup>) triggers the decomposition of hydrogen peroxide (H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub>) to yield reactive oxygen species (ROS), and the other involves the complexation of H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub> on the Ce<jats:sup>3+<\/jats:sup> surface, leading to the formation of peroxides. However, the influence of diverse CeO<jats:sub>2<\/jats:sub> morphologies on these two reaction pathways has not been comprehensively explored. In this study, CeO<jats:sub>2<\/jats:sub> exhibiting three typical morphologies, rods, cubes, and spheres, were prepared. The generation of ROS and peroxides was evaluated using the 3,3,5,5\u2010tetramethylbenzidine (TMB) oxidation reaction and the reduction current of H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub>, respectively. Moreover, the impacts of pH variations and CeO<jats:sub>2<\/jats:sub>\/H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub> concentrations on the production and conversion of these two reaction products were investigated. To corroborate the distinctions between the resultant products and their applicability, apoptosis assays and acid orange 7 (AO7) degradation analyses were performed. Notably, CeO<jats:sub>2<\/jats:sub> rods exhibited the highest proportion of Ce<jats:sup>3+<\/jats:sup>, predominantly engaging in complexation with H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub> to foster peroxide formation, thereby facilitating the robust degradation of AO7. However, the generated peroxides appeared to occupy Ce<jats:sup>3+<\/jats:sup> sites, thereby impeding the H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub> decomposition process. Conversely, Ce<jats:sup>3+<\/jats:sup> species on the surface of CeO<jats:sub>2<\/jats:sub> cubes were primarily involved in H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub> decomposition, leading to heightened ROS production, and thus showcasing substantial potential for damaging A549 tumor cells. It is worth noting that the ability of these Ce<jats:sup>3+<\/jats:sup> species to form peroxides through complexation with H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub> was comparatively reduced. In summation, this study sheds light on the intricate interplay between distinct CeO<jats:sub>2<\/jats:sub> morphologies and their divergent impacts on Fenton\u2010like reactions. These findings expand our comprehension of the influences on its reactivity of CeO<jats:sub>2<\/jats:sub> morphologies and open new insights for applications in diverse domains, from organic dye degradation to tumor therapy.<\/jats:p>","DOI":"10.1002\/cphc.202300211","type":"journal-article","created":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T13:59:57Z","timestamp":1692799197000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["A Detailed Insight into the Effects of Morphologies of Cerium Oxide on Fenton\u2010like Reactions for Different Applications"],"prefix":"10.1002","volume":"24","author":[{"given":"Meijuan","family":"Ding","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine Cancer Hospital of Harbin Medical University  150 Haping Road, Nangang District 150001 Harbin China"},{"name":"Department of Oncology Second Affifiliated Hospital of Harbin Medical University  246 Xuefu Road, Nangang District 150086 Harbin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dexin","family":"Jia","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Cancer Hospital of Harbin Medical University  150 Haping Road, Nangang District 150001 Harbin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Cancer Hospital of Harbin Medical University  150 Haping Road, Nangang District 150001 Harbin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Cancer Hospital of Harbin Medical University  150 Haping Road, Nangang District 150001 Harbin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guochang","family":"Lin","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Science and Technology on Advanced Composites in Special Environments Harbin Institute of Technology  92 Xidazhi Road, Nangang District 150001 Harbin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2466-5600","authenticated-orcid":false,"given":"Xuelin","family":"Zhang","sequence":"additional","affiliation":[{"name":"MEMS Center Harbin Institute of Technology  92 Xidazhi Road, Nangang District 150001 Harbin China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,9,27]]},"reference":[{"key":"e_1_2_9_1_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13346-013-0136-0"},{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/tpj.13299"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2012.01.008"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2021.08.018"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2010.04.067"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2013.10.043"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-012-1279-0"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2020.123949"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.9b09671"},{"key":"e_1_2_9_10_1","doi-asserted-by":"crossref","unstructured":"N. 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