{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T21:58:33Z","timestamp":1785362313004,"version":"3.55.0"},"reference-count":45,"publisher":"Wiley","issue":"14","license":[{"start":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T00:00:00Z","timestamp":1784851200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T00:00:00Z","timestamp":1784851200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ChemPhysChem"],"published-print":{"date-parts":[[2026,7,29]]},"abstract":"<jats:p>\n                    Hydrogen peroxide activated by a cobalt ferrite catalyst generates hydroxyl radicals that effectively inactivate bacteria. A continuous\u2010flow packed\u2010bed reactor containing cobalt ferrite was developed and tested for bacterial disinfection. The inactivation kinetics were highly nonlinear. The classical Weibull model accurately described the initial decline in bacterial counts at low H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    concentration (3\u2009mM) but lost accuracy at longer contact times and higher concentrations (6\u201310\u2009mM). To improve prediction, 10 machine learning algorithms were evaluated. Gradient boosting (GB) and random forest (RF) showed the best performance and were assessed using cross\u2010validation, error metrics, and independent validation with previously unseen data at 4\u2009mM H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    . GB demonstrated superior generalization, whereas RF was more accurate under moderate oxidative stress. A combined GB\u2009+\u2009RF model, based on averaging predictions from both algorithms, provided the most balanced results, with average errors below \u00b110% at low\u2010to\u2010moderate peroxide concentrations. The findings highlight the limitations of conventional kinetic models for cobalt ferrite\u2010catalyzed peroxide disinfection and provide a predictive framework for selecting peroxide dose and contact time in continuous\u2010flow treatment. Independent validation confirmed high predictive accuracy, with larger relative errors observed only at very low residual bacterial counts.\n                  <\/jats:p>","DOI":"10.1002\/cphc.70504","type":"journal-article","created":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T01:39:47Z","timestamp":1784943587000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Predictive Modeling of Bacterial Inactivation With Hydrogen Peroxide Over a Cobalt Ferrite Catalyst"],"prefix":"10.1002","volume":"27","author":[{"given":"Viktor","family":"Husak","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Biotechnology Vasyl Stefanyk Carpathian National University  Ivano\u2010Frankivsk Ukraine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazarii","family":"Danyliuk","sequence":"additional","affiliation":[{"name":"Educational and Scientific Center of Materials Science and Nanotechnology Vasyl Stefanyk Carpathian National University  Ivano\u2010Frankivsk Ukraine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7498-4140","authenticated-orcid":false,"given":"Hynek","family":"Roubik","sequence":"additional","affiliation":[{"name":"Department of Food and BioResource Technology Faculty of Tropical AgriSciences Czech University of Life Sciences  Prague Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olena","family":"Bobrova","sequence":"additional","affiliation":[{"name":"Czech Agrifood Research Center Plant Physiology and Cryobiology Team  Prague Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacy Denise Hammond","family":"Hammond","sequence":"additional","affiliation":[{"name":"Department of Food and BioResource Technology Faculty of Tropical AgriSciences Czech University of Life Sciences  Prague Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Shyichuk","sequence":"additional","affiliation":[{"name":"Educational and Scientific Center of Materials Science and Nanotechnology Vasyl Stefanyk Carpathian National University  Ivano\u2010Frankivsk Ukraine"},{"name":"Faculty of Chemical Technology and Engineering Bydgoszcz University of Science and Technology  Bydgoszcz Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,24]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dwt.2025.101340"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010024\u201084094\u20109"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2023.115598"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jwpe.2025.108126"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2025.137833"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfp.2024.100306"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijhydene.2022.07.231"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2023.131393"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cattod.2024.114562"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jwpe.2024.106756"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jece.2022.107347"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2023.169580"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13762\u2010022\u201004732\u20105"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2022.115028"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jwpe.2024.105870"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jenvman.2024.121971"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2024.156048"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seppur.2024.127748"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2024.216198"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/su152015183"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/nano14201640"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2EW00886F"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mran.2024.100294"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/1750\u20103841.13783"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jwpe.2018.09.001"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cattod.2024.114520"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.2c09824"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2020.126673"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclepro.2024.144171"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jwpe.2025.108344"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2025.138048"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jece.2024.114481"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.3390\/app15158195"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsusc.2025.162610"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/jfpe.70149"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seppur.2020.118242"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.4315\/0362\u2010028X\u201070.10.2281"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ese.2025.100557"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1177\/1082013215624807"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1177\/1082013220913357"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168\u20101605(03)00064\u20103"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2004.10.005"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2025.123541"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jenvman.2023.118116"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10668\u2010025\u201006009\u20106"}],"container-title":["ChemPhysChem"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cphc.70504","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cphc.70504","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cphc.70504","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T21:10:17Z","timestamp":1785359417000},"score":1,"resource":{"primary":{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/10.1002\/cphc.70504"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,24]]},"references-count":45,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2026,7,29]]}},"alternative-id":["10.1002\/cphc.70504"],"URL":"https:\/\/doi.org\/10.1002\/cphc.70504","archive":["Portico"],"relation":{},"ISSN":["1439-4235","1439-7641"],"issn-type":[{"value":"1439-4235","type":"print"},{"value":"1439-7641","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,24]]},"assertion":[{"value":"2026-03-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70504"}}