{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T10:41:58Z","timestamp":1789987318220,"version":"4.0.1"},"edition-number":"1","reference-count":336,"publisher":"Wiley","isbn-type":[{"value":"9780470650714","type":"electronic"}],"license":[{"start":{"date-parts":[[2014,12,23]],"date-time":"2014-12-23T00:00:00Z","timestamp":1419292800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"DOI":"10.1002\/cphy.c140019","type":"other","created":{"date-parts":[[2014,12,24]],"date-time":"2014-12-24T09:00:54Z","timestamp":1419411654000},"page":"217-253","source":"Crossref","is-referenced-by-count":25,"title":["Hypothalamus as an Endocrine Organ"],"prefix":"10.1002","author":[{"given":"I.J.","family":"Clarke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,12,23]]},"reference":[{"key":"e_1_2_17_2_1","doi-asserted-by":"crossref","first-page":"5771","DOI":"10.1523\/JNEUROSCI.23-13-05771.2003","article-title":"Estrogen receptor beta mediates rapid estrogen actions on gonadotropin\u2010releasing hormone neurons in vivo","volume":"23","author":"Abraham IM","year":"2003","journal-title":"J Neurosci"},{"key":"e_1_2_17_3_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2006-0576"},{"key":"e_1_2_17_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00219949"},{"key":"e_1_2_17_5_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-126-4-1989"},{"key":"e_1_2_17_6_1","doi-asserted-by":"publisher","DOI":"10.1006\/frne.1996.0001"},{"key":"e_1_2_17_7_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-128-1-65"},{"key":"e_1_2_17_8_1","first-page":"291","article-title":"Blood supply of the rat hypothalamus. I. Nucleus supraopticus","volume":"22","author":"Ambach G","year":"1974","journal-title":"Acta Morphol Acad Sci Hung"},{"key":"e_1_2_17_9_1","first-page":"93","article-title":"Blood supply of the rat hypothalamus. IV. Retrochiasmatic area, median eminence, arcuate nucleus","volume":"24","author":"Ambach G","year":"1976","journal-title":"Acta Morphol Acad Sci Hung"},{"key":"e_1_2_17_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-291X(71)80179-1"},{"key":"e_1_2_17_11_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2011-1622"},{"key":"e_1_2_17_12_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6879204"},{"key":"e_1_2_17_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000123492"},{"key":"e_1_2_17_14_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2013-1889"},{"key":"e_1_2_17_15_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-128-2-997"},{"key":"e_1_2_17_16_1","doi-asserted-by":"publisher","DOI":"10.2170\/jjphysiol.15.278"},{"key":"e_1_2_17_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(80)90040-8"},{"key":"e_1_2_17_18_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.85.23.9331"},{"key":"e_1_2_17_19_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2009-0604"},{"key":"e_1_2_17_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2013.12.015"},{"key":"e_1_2_17_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-9781(99)00139-4"},{"key":"e_1_2_17_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/0361-9230(85)90153-4"},{"key":"e_1_2_17_23_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1470565"},{"key":"e_1_2_17_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(76)90056-2"},{"key":"e_1_2_17_25_1","volume-title":"Annual Seminar Weekend of the Australian Society of Endocrinology","author":"Bartolini D","year":"2012"},{"key":"e_1_2_17_26_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.139.10.4175"},{"key":"e_1_2_17_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00306908"},{"key":"e_1_2_17_28_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-106-3-690"},{"key":"e_1_2_17_29_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-100-2-452"},{"key":"e_1_2_17_30_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-110-6-1861"},{"key":"e_1_2_17_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(80)90046-3"},{"key":"e_1_2_17_32_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-102-5-1325"},{"key":"e_1_2_17_33_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo.139.8.6154"},{"key":"e_1_2_17_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(73)90371-5"},{"key":"e_1_2_17_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/0361-9230(83)90124-7"},{"key":"e_1_2_17_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/0167-0115(82)90107-0"},{"key":"e_1_2_17_37_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.138.3.1019"},{"key":"e_1_2_17_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(69)90868-7"},{"key":"e_1_2_17_39_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.140.12.5929"},{"key":"e_1_2_17_40_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.179.4068.77"},{"key":"e_1_2_17_41_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2011-2005"},{"key":"e_1_2_17_42_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0510405"},{"key":"e_1_2_17_43_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.69.1.278"},{"key":"e_1_2_17_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00489916"},{"key":"e_1_2_17_45_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-125-5-2532"},{"key":"e_1_2_17_46_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1620215"},{"key":"e_1_2_17_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2012.02283.x"},{"key":"e_1_2_17_48_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo.139.4.5904"},{"key":"e_1_2_17_49_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI114626"},{"key":"e_1_2_17_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-291X(88)80572-2"},{"key":"e_1_2_17_51_1","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0820263"},{"key":"e_1_2_17_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/jne.12030"},{"key":"e_1_2_17_53_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2009-0541"},{"key":"e_1_2_17_54_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1213594110"},{"key":"e_1_2_17_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2010.10.019"},{"key":"e_1_2_17_56_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2009-0584"},{"key":"e_1_2_17_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2006.05.041"},{"key":"e_1_2_17_58_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0877-06.2006"},{"key":"e_1_2_17_59_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1190397"},{"key":"e_1_2_17_60_1","first-page":"54","article-title":"GnRH and ovarian hormone feedback","volume":"9","author":"Clarke IJ","year":"1987","journal-title":"Oxf Rev Reprod Biol"},{"key":"e_1_2_17_61_1","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1210\/endo.133.4.8404603","article-title":"Variable patterns of gonadotropin\u2010releasing hormone secretion during the estrogen\u2010induced luteinizing hormone surge in ovariectomized ewes","volume":"133","author":"Clarke IJ","year":"1993","journal-title":"Endocrinology"},{"key":"e_1_2_17_62_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1450271"},{"key":"e_1_2_17_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/1043-2760(95)95218-T"},{"key":"e_1_2_17_64_1","first-page":"45","volume-title":"Effector Mechanisms of the Hypothalamus that Regulate the Anterior Pituitary Gland","author":"Clarke IJ","year":"1996"},{"key":"e_1_2_17_65_1","first-page":"120","volume-title":"Scientific Essentials of Reproductive Medicine","author":"Clarke IJ","year":"1996"},{"key":"e_1_2_17_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2014.02.005"},{"key":"e_1_2_17_67_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2004-1085"},{"key":"e_1_2_17_68_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1110043"},{"key":"e_1_2_17_69_1","first-page":"135","volume-title":"Opioids and Reproduction","author":"Clarke IJ","year":"1988"},{"key":"e_1_2_17_70_1","first-page":"198","volume-title":"Handbook of Neuroendocrinology","author":"Clarke IJ","year":"2011"},{"key":"e_1_2_17_71_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-111-5-1737"},{"key":"e_1_2_17_72_1","doi-asserted-by":"publisher","DOI":"10.1159\/000123990"},{"key":"e_1_2_17_73_1","doi-asserted-by":"publisher","DOI":"10.1159\/000123484"},{"key":"e_1_2_17_74_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-127-3-1470"},{"key":"e_1_2_17_75_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo.143.1.8644"},{"key":"e_1_2_17_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yfrne.2009.04.001"},{"key":"e_1_2_17_77_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2008-0575"},{"key":"e_1_2_17_78_1","first-page":"159","article-title":"The role of kisspeptin and gonadotropin inhibitory hormone (GnIH) in the seasonality of reproduction in sheep","volume":"67","author":"Clarke IJ","year":"2010","journal-title":"Soc Reprod Fertil Suppl"},{"key":"e_1_2_17_79_1","doi-asserted-by":"publisher","DOI":"10.1159\/000332822"},{"key":"e_1_2_17_80_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2009.01835.x"},{"key":"e_1_2_17_81_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2007-1260"},{"key":"e_1_2_17_82_1","volume-title":"The Principia: A New Translaiton","author":"Cohen B","year":"1999"},{"key":"e_1_2_17_83_1","doi-asserted-by":"publisher","DOI":"10.1093\/biolreprod\/8.3.277"},{"key":"e_1_2_17_84_1","doi-asserted-by":"publisher","DOI":"10.1210\/me.2002-0398"},{"key":"e_1_2_17_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(03)00063-1"},{"key":"e_1_2_17_86_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-105-3-636"},{"key":"e_1_2_17_87_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI30227"},{"key":"e_1_2_17_88_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5486-09.2010"},{"key":"e_1_2_17_89_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2007-1487"},{"key":"e_1_2_17_90_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.135.6.2392"},{"key":"e_1_2_17_91_1","first-page":"1","article-title":"Studies of the hypothalamus and the pituitary gland with special reference to the effects of transection of the pituitary stalk","volume":"201","author":"Daniel PM","year":"1975","journal-title":"Acta Endocrinol Suppl (Copenh)"},{"key":"e_1_2_17_92_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2008.01784.x"},{"key":"e_1_2_17_93_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2826.2003.01060.x"},{"key":"e_1_2_17_94_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0057972"},{"key":"e_1_2_17_95_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0057972"},{"key":"e_1_2_17_96_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2012-1616"},{"key":"e_1_2_17_97_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1050107"},{"key":"e_1_2_17_98_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.19.3.269"},{"key":"e_1_2_17_99_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1834399100"},{"key":"e_1_2_17_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(82)91260-4"},{"key":"e_1_2_17_101_1","first-page":"175","article-title":"The primary plexus of the hypophyseal portal system","volume":"51","author":"Duvernoy H","year":"1968","journal-title":"Arch Anat Histol Embryol"},{"key":"e_1_2_17_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2014.03.009"},{"key":"e_1_2_17_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(88)90742-8"},{"key":"e_1_2_17_104_1","doi-asserted-by":"publisher","DOI":"10.1159\/000125139"},{"key":"e_1_2_17_105_1","doi-asserted-by":"publisher","DOI":"10.1159\/000125062"},{"key":"e_1_2_17_106_1","doi-asserted-by":"publisher","DOI":"10.1159\/000125141"},{"key":"e_1_2_17_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2007.02.004"},{"key":"e_1_2_17_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/0301-0082(86)90012-2"},{"key":"e_1_2_17_109_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2006.01485.x"},{"key":"e_1_2_17_110_1","doi-asserted-by":"publisher","DOI":"10.1210\/me.2013-1095"},{"key":"e_1_2_17_111_1","doi-asserted-by":"publisher","DOI":"10.1159\/000125214"},{"key":"e_1_2_17_112_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2004-0111"},{"key":"e_1_2_17_113_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(81)90006-3"},{"key":"e_1_2_17_114_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1440323"},{"key":"e_1_2_17_115_1","doi-asserted-by":"publisher","DOI":"10.1159\/000126722"},{"key":"e_1_2_17_116_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2006.03.039"},{"key":"e_1_2_17_117_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-114-4-1059"},{"key":"e_1_2_17_118_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI114681"},{"key":"e_1_2_17_119_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.2845584"},{"key":"e_1_2_17_120_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2003.11.066"},{"key":"e_1_2_17_121_1","doi-asserted-by":"publisher","DOI":"10.1159\/000125744"},{"key":"e_1_2_17_122_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-102-6-1895"},{"key":"e_1_2_17_123_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2008-0316"},{"key":"e_1_2_17_124_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-104-5-1407"},{"key":"e_1_2_17_125_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.1990.tb00846.x"},{"key":"e_1_2_17_126_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2012-1550"},{"key":"e_1_2_17_127_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2007-0961"},{"key":"e_1_2_17_128_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2012-1611"},{"key":"e_1_2_17_129_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4757-3565-9"},{"key":"e_1_2_17_130_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2004-0431"},{"key":"e_1_2_17_131_1","doi-asserted-by":"publisher","DOI":"10.1159\/000126214"},{"key":"e_1_2_17_132_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001560208"},{"key":"e_1_2_17_133_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod52.1.139"},{"key":"e_1_2_17_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(81)90606-5"},{"key":"e_1_2_17_135_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-104-3-583"},{"key":"e_1_2_17_136_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3328-05.2005"},{"key":"e_1_2_17_137_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2011.02206.x"},{"key":"e_1_2_17_138_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2008.06.076"},{"key":"e_1_2_17_139_1","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/BF00349134","article-title":"The neurohypophysis in the series of mammals","volume":"39","author":"Hanstrom B","year":"1953","journal-title":"Z Zellforsch Mikrosk Anat"},{"key":"e_1_2_17_140_1","first-page":"298","volume-title":"Neural Control of the Pituitary Gland","author":"Harris GW","year":"1955"},{"key":"e_1_2_17_141_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.139.1.57"},{"key":"e_1_2_17_142_1","doi-asserted-by":"publisher","DOI":"10.1210\/edrv.19.3.0332"},{"key":"e_1_2_17_143_1","doi-asserted-by":"publisher","DOI":"10.1159\/000126433"},{"key":"e_1_2_17_144_1","doi-asserted-by":"publisher","DOI":"10.1159\/000126948"},{"key":"e_1_2_17_145_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2011-1228"},{"key":"e_1_2_17_146_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2826.1998.00243.x"},{"key":"e_1_2_17_147_1","doi-asserted-by":"publisher","DOI":"10.1159\/000350790"},{"key":"e_1_2_17_148_1","first-page":"88","volume-title":"Structure and Function of Peptidergic and Aminergic Neurons","author":"Hoffman GE","year":"1983"},{"key":"e_1_2_17_149_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(82)90012-4"},{"key":"e_1_2_17_150_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2010-0066"},{"key":"e_1_2_17_151_1","doi-asserted-by":"publisher","DOI":"10.1016\/0028-3908(88)90116-5"},{"key":"e_1_2_17_152_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(89)90479-4"},{"key":"e_1_2_17_153_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2010.07239.x"},{"key":"e_1_2_17_154_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.141.9.3506"},{"key":"e_1_2_17_155_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2012-1545"},{"key":"e_1_2_17_156_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.142.7.3261"},{"key":"e_1_2_17_157_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(93)90094-4"},{"key":"e_1_2_17_158_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2005-0622"},{"key":"e_1_2_17_159_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2005.01319.x"},{"key":"e_1_2_17_160_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(00)02912-7"},{"key":"e_1_2_17_161_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod18.5.808"},{"key":"e_1_2_17_162_1","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.7.8.8500693"},{"key":"e_1_2_17_163_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2006.09.009"},{"key":"e_1_2_17_164_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-118-2-805"},{"key":"e_1_2_17_165_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.domaniend.2009.02.001"},{"key":"e_1_2_17_166_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410240610"},{"key":"e_1_2_17_167_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2012.02363.x"},{"key":"e_1_2_17_168_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.131.1.208"},{"key":"e_1_2_17_169_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-9781(99)00156-4"},{"key":"e_1_2_17_170_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-109-5-1739"},{"key":"e_1_2_17_171_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-118-5-1872"},{"key":"e_1_2_17_172_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2006-1540"},{"key":"e_1_2_17_173_1","doi-asserted-by":"publisher","DOI":"10.1159\/000123356"},{"key":"e_1_2_17_174_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902650208"},{"key":"e_1_2_17_175_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0361-9230(01)00638-4"},{"key":"e_1_2_17_176_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902090307"},{"key":"e_1_2_17_177_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2005-0195"},{"key":"e_1_2_17_178_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0901176106"},{"key":"e_1_2_17_179_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.81.6.1854"},{"key":"e_1_2_17_180_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-98-2-311"},{"key":"e_1_2_17_181_1","doi-asserted-by":"publisher","DOI":"10.1177\/002215540205001209"},{"key":"e_1_2_17_182_1","doi-asserted-by":"publisher","DOI":"10.1038\/45230"},{"key":"e_1_2_17_183_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2005.01374.x"},{"key":"e_1_2_17_184_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.900550104"},{"key":"e_1_2_17_185_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4614-6199-9_18"},{"key":"e_1_2_17_186_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0511003103"},{"key":"e_1_2_17_187_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.18.8462"},{"key":"e_1_2_17_188_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-111-1-55"},{"key":"e_1_2_17_189_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2012.02360.x"},{"key":"e_1_2_17_190_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2010-0022"},{"key":"e_1_2_17_191_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0361-9230(97)00225-6"},{"key":"e_1_2_17_192_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.133.2.887"},{"key":"e_1_2_17_193_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902440103"},{"key":"e_1_2_17_194_1","doi-asserted-by":"publisher","DOI":"10.1159\/000335998"},{"key":"e_1_2_17_195_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-116-3-966"},{"key":"e_1_2_17_196_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00493148"},{"key":"e_1_2_17_197_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00496811"},{"key":"e_1_2_17_198_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI117121"},{"key":"e_1_2_17_199_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5759-10.2011"},{"key":"e_1_2_17_200_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(77)90501-7"},{"key":"e_1_2_17_201_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(01)02544-7"},{"key":"e_1_2_17_202_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-124-3-1522"},{"key":"e_1_2_17_203_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo.140.8.6943"},{"key":"e_1_2_17_204_1","first-page":"43","article-title":"The relative importance of hypothalamic neurons containing corticotropin\u2010releasing factor or vasopressin in the regulation of adrenocorticotropic hormone secretion","volume":"168","author":"Makara GB","year":"1992","journal-title":"Ciba Found Symp"},{"key":"e_1_2_17_205_1","doi-asserted-by":"publisher","DOI":"10.1210\/mend.13.10.0351"},{"key":"e_1_2_17_206_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(00)02520-8"},{"key":"e_1_2_17_207_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(80)90170-5"},{"key":"e_1_2_17_208_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-291X(71)80019-0"},{"key":"e_1_2_17_209_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.136.5.1821"},{"key":"e_1_2_17_210_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(92)91138-5"},{"key":"e_1_2_17_211_1","first-page":"594","volume-title":"The Human Nervous System","author":"McKinley MJ","year":"1990"},{"key":"e_1_2_17_212_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-114-4-1082"},{"key":"e_1_2_17_213_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2012-1357"},{"key":"e_1_2_17_214_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0409330102"},{"key":"e_1_2_17_215_1","doi-asserted-by":"publisher","DOI":"10.1071\/RD10150"},{"key":"e_1_2_17_216_1","doi-asserted-by":"publisher","DOI":"10.1159\/000125322"},{"key":"e_1_2_17_217_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.141.5.1772"},{"key":"e_1_2_17_218_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-127-3-1450"},{"key":"e_1_2_17_219_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2010-1418"},{"key":"e_1_2_17_220_1","doi-asserted-by":"publisher","DOI":"10.1159\/000125746"},{"key":"e_1_2_17_221_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05026"},{"key":"e_1_2_17_222_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.137.4.1171"},{"key":"e_1_2_17_223_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-121-1-205"},{"key":"e_1_2_17_224_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-102-4-1008"},{"key":"e_1_2_17_225_1","doi-asserted-by":"publisher","DOI":"10.1038\/35051587"},{"key":"e_1_2_17_226_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2011-2009"},{"key":"e_1_2_17_227_1","doi-asserted-by":"publisher","DOI":"10.1016\/0196-9781(88)90169-6"},{"key":"e_1_2_17_228_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.2009-0005"},{"key":"e_1_2_17_229_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2009.01909.x"},{"key":"e_1_2_17_230_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2012-1066"},{"key":"e_1_2_17_231_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-101-2-598"},{"key":"e_1_2_17_232_1","first-page":"R1247","article-title":"Heterogeneous neurochemical responses to different stressors: A test of Selye's doctrine of nonspecificity","volume":"275","author":"Pacak K","year":"1998","journal-title":"Am J Physiol"},{"key":"e_1_2_17_233_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2010.02094.x"},{"key":"e_1_2_17_234_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI109433"},{"key":"e_1_2_17_235_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2005-1533"},{"key":"e_1_2_17_236_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.7256264"},{"key":"e_1_2_17_237_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-114-1-164"},{"key":"e_1_2_17_238_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00216766"},{"key":"e_1_2_17_239_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.10805"},{"key":"e_1_2_17_240_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(01)02372-1"},{"key":"e_1_2_17_241_1","first-page":"88","article-title":"A portal circulation from the pituitary to the hypothalamic region","volume":"65","author":"Popa G.","year":"1930","journal-title":"J Anat"},{"key":"e_1_2_17_242_1","first-page":"161","article-title":"Neurovascular regulation of the anterior hypophysis","volume":"29","author":"Porter JC","year":"1973","journal-title":"Recent Prog Horm Res"},{"key":"e_1_2_17_243_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.90377.2008"},{"key":"e_1_2_17_244_1","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1111\/j.1365-2826.2010.02033.x","article-title":"Gonadotrophin\u2010releasing hormone nerve terminals, tanycytes and neurohaemal junction remodelling in the adult median eminence: Functional consequences for reproduction and dynamic role of vascular endothelial cells","volume":"22","author":"Prevot V","journal-title":"J Neuroendocrinol"},{"key":"e_1_2_17_245_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(99)00383-8"},{"key":"e_1_2_17_246_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yfrne.2010.05.003"},{"key":"e_1_2_17_247_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2009.01886.x"},{"key":"e_1_2_17_248_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11154-007-9031-7"},{"key":"e_1_2_17_249_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2006.07.025"},{"key":"e_1_2_17_250_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-111-4-1051"},{"key":"e_1_2_17_251_1","doi-asserted-by":"publisher","DOI":"10.1016\/0361-9230(81)90100-3"},{"key":"e_1_2_17_252_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2005.01.045"},{"key":"e_1_2_17_253_1","doi-asserted-by":"publisher","DOI":"10.1038\/305325a0"},{"key":"e_1_2_17_254_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2012-1133"},{"key":"e_1_2_17_255_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2008-1287"},{"key":"e_1_2_17_256_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2826.2000.00426.x"},{"key":"e_1_2_17_257_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-86-3-568"},{"key":"e_1_2_17_258_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0074-7696(05)47003-5"},{"key":"e_1_2_17_259_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00757.2002"},{"key":"e_1_2_17_260_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2009-0775"},{"key":"e_1_2_17_261_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-123-4-1928"},{"key":"e_1_2_17_262_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2005-0174"},{"key":"e_1_2_17_263_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.103.017848"},{"key":"e_1_2_17_264_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1212137110"},{"key":"e_1_2_17_265_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(71)90766-2"},{"key":"e_1_2_17_266_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1954.tb08198.x"},{"key":"e_1_2_17_267_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa035322"},{"key":"e_1_2_17_268_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00319366"},{"key":"e_1_2_17_269_1","doi-asserted-by":"publisher","DOI":"10.1038\/304345a0"},{"key":"e_1_2_17_270_1","doi-asserted-by":"publisher","DOI":"10.1002\/syn.890060206"},{"key":"e_1_2_17_271_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.22126"},{"key":"e_1_2_17_272_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.138.10.4220"},{"key":"e_1_2_17_273_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo.138.6.5208"},{"key":"e_1_2_17_274_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.1992.tb00216.x"},{"key":"e_1_2_17_275_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.peptides.2008.08.013"},{"key":"e_1_2_17_276_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2006-1435"},{"key":"e_1_2_17_277_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2008-0581"},{"key":"e_1_2_17_278_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2005-0488"},{"key":"e_1_2_17_279_1","doi-asserted-by":"publisher","DOI":"10.1016\/0196-9781(81)90011-5"},{"key":"e_1_2_17_280_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2009-0712"},{"key":"e_1_2_17_281_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2010-1225"},{"key":"e_1_2_17_282_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1618-06.2006"},{"key":"e_1_2_17_283_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2007-1425"},{"key":"e_1_2_17_284_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2012-1088"},{"key":"e_1_2_17_285_1","doi-asserted-by":"publisher","DOI":"10.1159\/000227806"},{"key":"e_1_2_17_286_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.110.085407"},{"key":"e_1_2_17_287_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2012-1088"},{"key":"e_1_2_17_288_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2013-1786"},{"key":"e_1_2_17_289_1","doi-asserted-by":"publisher","DOI":"10.1016\/0739-7240(91)90049-P"},{"key":"e_1_2_17_290_1","doi-asserted-by":"publisher","DOI":"10.1677\/JOE-08-0421"},{"key":"e_1_2_17_291_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.23.13203"},{"key":"e_1_2_17_292_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0305930101"},{"key":"e_1_2_17_293_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2007.01551.x"},{"key":"e_1_2_17_294_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2002-220852"},{"key":"e_1_2_17_295_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-115-5-1952"},{"key":"e_1_2_17_296_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-127-5-2551"},{"key":"e_1_2_17_297_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo.140.3.6559"},{"key":"e_1_2_17_298_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2010.02027.x"},{"key":"e_1_2_17_299_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-125-4-2204"},{"key":"e_1_2_17_300_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1110425"},{"key":"e_1_2_17_301_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-128-2-1151"},{"key":"e_1_2_17_302_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1110433"},{"key":"e_1_2_17_303_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1170115"},{"key":"e_1_2_17_304_1","doi-asserted-by":"publisher","DOI":"10.1159\/000126127"},{"key":"e_1_2_17_305_1","first-page":"83","article-title":"In vivo observation of pituitary circulation in dog","volume":"4","author":"Torok B.","year":"1954","journal-title":"Acta Morphol Acad Sci Hung"},{"key":"e_1_2_17_306_1","doi-asserted-by":"publisher","DOI":"10.1159\/000123595"},{"key":"e_1_2_17_307_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2013.00060"},{"key":"e_1_2_17_308_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2013.00038"},{"key":"e_1_2_17_309_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2011-1110"},{"key":"e_1_2_17_310_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.22191"},{"key":"e_1_2_17_311_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0008400"},{"key":"e_1_2_17_312_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.1996.tb00693.x"},{"key":"e_1_2_17_313_1","doi-asserted-by":"publisher","DOI":"10.1159\/000048224"},{"key":"e_1_2_17_314_1","doi-asserted-by":"publisher","DOI":"10.1677\/JME-09-0023"},{"key":"e_1_2_17_315_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5848-09.2010"},{"key":"e_1_2_17_316_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1001341"},{"key":"e_1_2_17_317_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-120-5-1846"},{"key":"e_1_2_17_318_1","doi-asserted-by":"publisher","DOI":"10.1530\/JME-12-0068"},{"key":"e_1_2_17_319_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-111-6-2147"},{"key":"e_1_2_17_320_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-107-6-1747"},{"key":"e_1_2_17_321_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-46262-7"},{"key":"e_1_2_17_322_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.9.4149"},{"key":"e_1_2_17_323_1","doi-asserted-by":"publisher","DOI":"10.1159\/000054491"},{"key":"e_1_2_17_324_1","doi-asserted-by":"publisher","DOI":"10.1679\/aohc.58.31"},{"key":"e_1_2_17_325_1","doi-asserted-by":"publisher","DOI":"10.1159\/000123988"},{"key":"e_1_2_17_326_1","first-page":"58","volume-title":"The Pituitary Gland","author":"Wingstrand KG","year":"1966"},{"key":"e_1_2_17_327_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2006.07.023"},{"key":"e_1_2_17_328_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00215463"},{"key":"e_1_2_17_329_1","first-page":"285","article-title":"The pars tuberalis of the hypophysis: A modulator of the pars distalis","volume":"126","author":"Wittkowski WH","year":"1992","journal-title":"Acta Endocrinol (Copenh)"},{"key":"e_1_2_17_330_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.130.4.2333"},{"key":"e_1_2_17_331_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-128-2-1144"},{"key":"e_1_2_17_332_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0402763101"},{"key":"e_1_2_17_333_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902520408"},{"key":"e_1_2_17_334_1","doi-asserted-by":"publisher","DOI":"10.1159\/000066629"},{"key":"e_1_2_17_335_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2007-1551"},{"key":"e_1_2_17_336_1","doi-asserted-by":"publisher","DOI":"10.1159\/000336376"},{"key":"e_1_2_17_337_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2003-0241"}],"container-title":["Comprehensive Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cphy.c140019","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cphy.c140019","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cphy.c140019","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T23:57:39Z","timestamp":1717631859000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cphy.c140019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12,23]]},"ISBN":["9780470650714"],"references-count":336,"alternative-id":["10.1002\/cphy.c140019","10.1002\/cphy"],"URL":"https:\/\/doi.org\/10.1002\/cphy.c140019","archive":["Portico"],"relation":{},"subject":[],"published":{"date-parts":[[2014,12,23]]}}}