{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T16:37:41Z","timestamp":1791045461384,"version":"4.1.0"},"edition-number":"1","reference-count":468,"publisher":"Wiley","isbn-type":[{"value":"9780470650714","type":"electronic"}],"license":[{"start":{"date-parts":[[2017,12,12]],"date-time":"2017-12-12T00:00:00Z","timestamp":1513036800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Solid tumor growth and metastasis require the interaction of tumor cells with the surrounding tissue, leading to a view of tumors as tissue\u2010level phenomena rather than exclusively cell\u2010intrinsic anomalies. Due to the ubiquitous nature of adipose tissue, many types of solid tumors grow in proximate or direct contact with adipocytes and adipose\u2010associated stromal and vascular components, such as fibroblasts and other connective tissue cells, stem and progenitor cells, endothelial cells, innate and adaptive immune cells, and extracellular signaling and matrix components. Excess adiposity in obesity both increases risk of cancer development and negatively influences prognosis in several cancer types, in part due to interaction with adipose tissue cell populations. Herein, we review the cellular and noncellular constituents of the adipose \u201corgan,\u201d and discuss the mechanisms by which these varied microenvironmental components contribute to tumor development, with special emphasis on obesity. Due to the prevalence of breast and prostate cancers in the United States, their close anatomical proximity to adipose tissue depots, and their complex epidemiologic associations with obesity, we particularly highlight research addressing the contribution of adipose tissue to the initiation and progression of these cancer types. Obesity dramatically modifies the adipose tissue microenvironment in numerous ways, including induction of fibrosis and angiogenesis, increased stem cell abundance, and expansion of proinflammatory immune cells. As many of these changes also resemble shifts observed within the tumor microenvironment, proximity to adipose tissue may present a hospitable environment to developing tumors, providing a critical link between adiposity and tumorigenesis. \u00a9 2018 American Physiological Society.\n                    <jats:italic>Compr Physiol<\/jats:italic>\n                    8:237\u2010282, 2018.\n                  <\/jats:p>","DOI":"10.1002\/cphy.c170008","type":"other","created":{"date-parts":[[2017,12,11]],"date-time":"2017-12-11T02:57:11Z","timestamp":1512961031000},"page":"237-282","source":"Crossref","is-referenced-by-count":128,"title":["Contribution of Adipose Tissue to Development of Cancer"],"prefix":"10.1002","author":[{"given":"Alyssa J.","family":"Cozzo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley M.","family":"Fuller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liza","family":"Makowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,12,12]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"The Human Protein Atlas www.proteinatlas.org. Human breast cancer \u2010 Female 50 years lobular carcinoma grade 1 Elston\u2010Ellis score 5. Image data available at the following URL:v16.proteinatlas.org\/learn\/dictionary\/cancer\/breast+cancer+4."},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-06-0356"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2009.06.020"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-4585"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2008.03037.x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2067"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1387\/ijdb.103226ia"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2016.04.029"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M011338"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/1476-511X-10-198"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-017-3178-8"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12028"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2013.11.017"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3003130"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-015-2420-6"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1158\/1940-6207.CAPR-12-0091"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10555-006-9004-4"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-13-0926"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2012.98"},{"issue":"10","key":"e_1_2_10_21_1","doi-asserted-by":"crossref","first-page":"2931","DOI":"10.1242\/jcs.107.10.2931","article-title":"Ectoenzyme regulation by phenotypically distinct fibroblast sub\u2010populations isolated from the human mammary gland","volume":"107","author":"Atherton AJ","year":"1994","journal-title":"J\u00a0Cell Sci"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004410051020"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2007.03.006"},{"key":"e_1_2_10_24_1","first-page":"4792","article-title":"Reactive stroma as a predictor of biochemical\u2010free recurrence in prostate cancer","volume":"9","author":"Ayala G","year":"2003","journal-title":"Clin Cancer Res"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13668-013-0068-9"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2013.00211"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1388"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2628"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)04046-0"},{"key":"e_1_2_10_30_1","first-page":"356","article-title":"PGE(2) contributes to TGF\u2010\u03b2 induced T regulatory cell function in human non\u2010small cell lung cancer","volume":"2","author":"Baratelli F","year":"2010","journal-title":"Am J Transl Res"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.175.3.1483"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20151080"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2015.0513"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11912-010-0139-7"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.05.9584"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12037"},{"key":"e_1_2_10_37_1","unstructured":"Baylor Breast Care Center BCoM.CRIZENT: Crizotinib and Sunitinib in Metastatic Breast Cancer. In:ClinicalTrials.govidentifier NCT02074878 2015."},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.27480"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2011.05.031"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00174.2006"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1093"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2011.38"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.3109\/09513590.2012.736559"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1101\/sqb.2005.70.013"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/35094059"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0310153"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-13-0530"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tec.2013.0683"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urolonc.2015.07.006"},{"key":"e_1_2_10_50_1","volume-title":"Urologic Surgical Pathology","author":"Bostwick DG","year":"2008"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcyt.2013.02.006"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djq239"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000132745.76882.70"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2009.02330.x"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1093\/epirev\/mxm012"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa021423"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1207751"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-010-1154-y"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-06-2538"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.101564798"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI32239"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3159"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexmp.2012.03.005"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1186\/bcr3476"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdu042"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1088\/1478-3975\/8\/1\/015008"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3415"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-016-3825-9"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI80011"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2013.04.023"},{"key":"e_1_2_10_71_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2009-0070"},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.10065"},{"key":"e_1_2_10_73_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature01322"},{"key":"e_1_2_10_74_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers7030828"},{"key":"e_1_2_10_75_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40064-016-1920-3"},{"key":"e_1_2_10_76_1","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.53.5.1285"},{"key":"e_1_2_10_77_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-006-0173-z"},{"key":"e_1_2_10_78_1","doi-asserted-by":"publisher","DOI":"10.1369\/0022155414545334"},{"key":"e_1_2_10_79_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1198973"},{"key":"e_1_2_10_80_1","doi-asserted-by":"publisher","DOI":"10.2217\/fon.10.33"},{"key":"e_1_2_10_81_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms2877"},{"key":"e_1_2_10_82_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201141817"},{"key":"e_1_2_10_83_1","doi-asserted-by":"publisher","DOI":"10.1111\/imm.12451"},{"key":"e_1_2_10_84_1","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-13-0196"},{"key":"e_1_2_10_85_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-07-1479"},{"key":"e_1_2_10_86_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00023.2015"},{"key":"e_1_2_10_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2013.02.013"},{"key":"e_1_2_10_88_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.23925"},{"key":"e_1_2_10_89_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-12-0107"},{"key":"e_1_2_10_90_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8274.CD-10-0028"},{"key":"e_1_2_10_91_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathol-012615-044359"},{"key":"e_1_2_10_92_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-06-1731"},{"key":"e_1_2_10_93_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-10-3323"},{"key":"e_1_2_10_94_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-04-1708"},{"key":"e_1_2_10_95_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012-1532"},{"key":"e_1_2_10_96_1","doi-asserted-by":"publisher","DOI":"10.2337\/db10-0585"},{"key":"e_1_2_10_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coi.2010.06.010"},{"key":"e_1_2_10_98_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0029(20010115)52:2<182::AID-JEMT1004>3.0.CO;2-M"},{"key":"e_1_2_10_99_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10911-015-9341-4"},{"key":"e_1_2_10_100_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a006536"},{"key":"e_1_2_10_101_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms6200"},{"key":"e_1_2_10_102_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198612253152606"},{"key":"e_1_2_10_103_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2002.10.088"},{"key":"e_1_2_10_104_1","first-page":"1388","article-title":"Heterogeneity of angiogenesis and blood vessel maturation in human tumors: Implications for antiangiogenic tumor therapies","volume":"60","author":"Eberhard A","year":"2000","journal-title":"Cancer Res"},{"key":"e_1_2_10_105_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1417636112"},{"key":"e_1_2_10_106_1","doi-asserted-by":"publisher","DOI":"10.1309\/2HGNJ1GU57JMBJAQ"},{"key":"e_1_2_10_107_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M800132-JLR200"},{"key":"e_1_2_10_108_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc.2016.54"},{"key":"e_1_2_10_109_1","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.1209821"},{"key":"e_1_2_10_110_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-14-0992"},{"key":"e_1_2_10_111_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.85096"},{"key":"e_1_2_10_112_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.29.7614"},{"key":"e_1_2_10_113_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0802594"},{"key":"e_1_2_10_114_1","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgw062"},{"key":"e_1_2_10_115_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.12154"},{"key":"e_1_2_10_116_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm0603-669"},{"key":"e_1_2_10_117_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2002"},{"key":"e_1_2_10_118_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.06.015"},{"key":"e_1_2_10_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2014.01.008"},{"key":"e_1_2_10_120_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2012.11.035"},{"key":"e_1_2_10_121_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.6458"},{"key":"e_1_2_10_122_1","doi-asserted-by":"publisher","DOI":"10.1002\/pros.20948"},{"key":"e_1_2_10_123_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni904"},{"key":"e_1_2_10_124_1","first-page":"4161","article-title":"Relationship of endothelial cell proliferation to tumor vascularity in human breast cancer","volume":"53","author":"Fox SB","year":"1993","journal-title":"Cancer Res"},{"key":"e_1_2_10_125_1","doi-asserted-by":"publisher","DOI":"10.1186\/bcr1796"},{"key":"e_1_2_10_126_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1252510"},{"key":"e_1_2_10_127_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.023820"},{"key":"e_1_2_10_128_1","first-page":"73","article-title":"Examining the relationship between obesity and prostate cancer","volume":"6","author":"Freedland SJ","year":"2004","journal-title":"Rev Urol"},{"key":"e_1_2_10_129_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.522037"},{"key":"e_1_2_10_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2009.06.017"},{"key":"e_1_2_10_131_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.83.3.847"},{"key":"e_1_2_10_132_1","doi-asserted-by":"publisher","DOI":"10.2337\/db08-1475"},{"key":"e_1_2_10_133_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-3037"},{"key":"e_1_2_10_134_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2506"},{"key":"e_1_2_10_135_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.21.120601.141025"},{"key":"e_1_2_10_136_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2006.01.025"},{"key":"e_1_2_10_137_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2016.96"},{"key":"e_1_2_10_138_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.20472"},{"key":"e_1_2_10_139_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2419"},{"key":"e_1_2_10_140_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M700131-JLR200"},{"key":"e_1_2_10_141_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2010.06.132"},{"key":"e_1_2_10_142_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00418-008-0537-1"},{"key":"e_1_2_10_143_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11033-014-3146-1"},{"key":"e_1_2_10_144_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-009-0797-6"},{"key":"e_1_2_10_145_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2016.02.024"},{"key":"e_1_2_10_146_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdu501"},{"key":"e_1_2_10_147_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc10-0666"},{"key":"e_1_2_10_148_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2013-1403"},{"key":"e_1_2_10_149_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature13989"},{"key":"e_1_2_10_150_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.113.071399"},{"key":"e_1_2_10_151_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.200737638"},{"key":"e_1_2_10_152_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10555-013-9487-8"},{"key":"e_1_2_10_153_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1203280"},{"key":"e_1_2_10_154_1","doi-asserted-by":"publisher","DOI":"10.4161\/cbt.11.10.15473"},{"key":"e_1_2_10_155_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-013-3139-y"},{"key":"e_1_2_10_156_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-12-172825"},{"key":"e_1_2_10_157_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20080108"},{"key":"e_1_2_10_158_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms6962"},{"key":"e_1_2_10_159_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.00192-09"},{"key":"e_1_2_10_160_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80108-7"},{"key":"e_1_2_10_161_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.02.013"},{"key":"e_1_2_10_162_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10555-013-9484-y"},{"key":"e_1_2_10_163_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3361"},{"key":"e_1_2_10_164_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1642"},{"key":"e_1_2_10_165_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2013.04.004"},{"key":"e_1_2_10_166_1","doi-asserted-by":"publisher","DOI":"10.2337\/db15-0090"},{"key":"e_1_2_10_167_1","doi-asserted-by":"publisher","DOI":"10.2527\/2004.823925x"},{"key":"e_1_2_10_168_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-04-0088"},{"key":"e_1_2_10_169_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1534-5807(01)00064-8"},{"key":"e_1_2_10_170_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.1482"},{"key":"e_1_2_10_171_1","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2007-8-5-r76"},{"key":"e_1_2_10_172_1","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2007.070112"},{"key":"e_1_2_10_173_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-1588"},{"key":"e_1_2_10_174_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.28386"},{"key":"e_1_2_10_175_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13058-015-0547-6"},{"key":"e_1_2_10_176_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1079490"},{"key":"e_1_2_10_177_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10911-010-9187-8"},{"key":"e_1_2_10_178_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-2630"},{"key":"e_1_2_10_179_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13058-015-0592-1"},{"key":"e_1_2_10_180_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-15-1177"},{"key":"e_1_2_10_181_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.087643"},{"key":"e_1_2_10_182_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.83.12.4464"},{"key":"e_1_2_10_183_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fob.2013.11.004"},{"key":"e_1_2_10_184_1","doi-asserted-by":"publisher","DOI":"10.1002\/pros.22972"},{"key":"e_1_2_10_185_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-12-4213"},{"key":"e_1_2_10_186_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1206737"},{"key":"e_1_2_10_187_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI23424"},{"key":"e_1_2_10_188_1","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2010.100070"},{"key":"e_1_2_10_189_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.2012.01151.x"},{"key":"e_1_2_10_190_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmet.2016.04.005"},{"key":"e_1_2_10_191_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.25.022106.141623"},{"key":"e_1_2_10_192_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.109.215715"},{"key":"e_1_2_10_193_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2013.06.050"},{"key":"e_1_2_10_194_1","doi-asserted-by":"publisher","DOI":"10.1158\/1541-7786.MCR-12-0307"},{"key":"e_1_2_10_195_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmet.2014.11.006"},{"key":"e_1_2_10_196_1","doi-asserted-by":"publisher","DOI":"10.1258\/ebm.2010.010227"},{"key":"e_1_2_10_197_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6603051"},{"key":"e_1_2_10_198_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2011.10754.x"},{"key":"e_1_2_10_199_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/574025"},{"key":"e_1_2_10_200_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.01300-08"},{"key":"e_1_2_10_201_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0030563"},{"key":"e_1_2_10_202_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature13528"},{"key":"e_1_2_10_203_1","doi-asserted-by":"publisher","DOI":"10.1093\/mutage\/gel032"},{"key":"e_1_2_10_204_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-59745-184-0_10"},{"key":"e_1_2_10_205_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61410-5"},{"key":"e_1_2_10_206_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2014.08.010"},{"key":"e_1_2_10_207_1","doi-asserted-by":"publisher","DOI":"10.2217\/14796694.3.5.557"},{"key":"e_1_2_10_208_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.174.8.4880"},{"key":"e_1_2_10_209_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.j477"},{"key":"e_1_2_10_210_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2010.06.019"},{"key":"e_1_2_10_211_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsr1606602"},{"key":"e_1_2_10_212_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms10230"},{"key":"e_1_2_10_213_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri3920"},{"key":"e_1_2_10_214_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2009.12.016"},{"key":"e_1_2_10_215_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1201-1291"},{"key":"e_1_2_10_216_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-16-0651"},{"key":"e_1_2_10_217_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mam.2012.10.001"},{"key":"e_1_2_10_218_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mvr.2012.04.004"},{"key":"e_1_2_10_219_1","first-page":"4625","article-title":"Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma","volume":"56","author":"Leek RD","year":"1996","journal-title":"Cancer Res"},{"key":"e_1_2_10_220_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11912-016-0539-4"},{"key":"e_1_2_10_221_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.10.027"},{"key":"e_1_2_10_222_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.100263"},{"key":"e_1_2_10_223_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-08-2164"},{"key":"e_1_2_10_224_1","doi-asserted-by":"publisher","DOI":"10.1038\/cmi.2009.53"},{"key":"e_1_2_10_225_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.58.4680"},{"key":"e_1_2_10_226_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvm007"},{"key":"e_1_2_10_227_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.9436"},{"key":"e_1_2_10_228_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-1278"},{"key":"e_1_2_10_229_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.1994"},{"key":"e_1_2_10_230_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-05-0042"},{"key":"e_1_2_10_231_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201102147"},{"key":"e_1_2_10_232_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI29881"},{"key":"e_1_2_10_233_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.147207"},{"key":"e_1_2_10_234_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2011.03842.x"},{"key":"e_1_2_10_235_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)65173-5"},{"key":"e_1_2_10_236_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20150295"},{"key":"e_1_2_10_237_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humimm.2009.02.008"},{"key":"e_1_2_10_238_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1471-4906(02)02302-5"},{"key":"e_1_2_10_239_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-14-534"},{"key":"e_1_2_10_240_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-010-0263-4"},{"key":"e_1_2_10_241_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.45.2722"},{"key":"e_1_2_10_242_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2011.12.011"},{"key":"e_1_2_10_243_1","doi-asserted-by":"publisher","DOI":"10.12703\/P6-13"},{"key":"e_1_2_10_244_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.177.10.7303"},{"key":"e_1_2_10_245_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaf4238"},{"key":"e_1_2_10_246_1","doi-asserted-by":"publisher","DOI":"10.1093\/asj\/sjv194"},{"key":"e_1_2_10_247_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.315200"},{"key":"e_1_2_10_248_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2013.07.016"},{"key":"e_1_2_10_249_1","doi-asserted-by":"publisher","DOI":"10.15252\/emmm.201404271"},{"key":"e_1_2_10_250_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-015-4908-2"},{"key":"e_1_2_10_251_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrep.2016.06.004"},{"key":"e_1_2_10_252_1","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1186\/1755-1536-5-S1-S5","article-title":"The myofibroblast, multiple origins for major roles in normal and pathological tissue repair","volume":"5","author":"Micallef L","year":"2012","journal-title":"Fibrogenesis & Tissue Repair"},{"key":"e_1_2_10_253_1","first-page":"2573","article-title":"Serum level of cathepsin B and its density in men with prostate cancer as novel markers of disease progression","volume":"24","author":"Miyake H","year":"2004","journal-title":"Anticancer Res"},{"key":"e_1_2_10_254_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-003-1221-6"},{"key":"e_1_2_10_255_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-003-1221-6"},{"key":"e_1_2_10_256_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms14010888"},{"key":"e_1_2_10_257_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2011.4"},{"key":"e_1_2_10_258_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20121964"},{"key":"e_1_2_10_259_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2012.01.002"},{"key":"e_1_2_10_260_1","first-page":"348","article-title":"Obesity inhibits lymphangiogenesis in prostate tumors","volume":"7","author":"Moreira \u00c2","year":"2014","journal-title":"Int J Clin Exp Pathol"},{"key":"e_1_2_10_261_1","doi-asserted-by":"publisher","DOI":"10.1158\/1940-6207.CAPR-11-0110"},{"key":"e_1_2_10_262_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.05.023"},{"key":"e_1_2_10_263_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2448"},{"key":"e_1_2_10_264_1","doi-asserted-by":"publisher","DOI":"10.1387\/ijdb.113385mm"},{"key":"e_1_2_10_265_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-09-4672"},{"key":"e_1_2_10_266_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M800019-JLR200"},{"key":"e_1_2_10_267_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2444"},{"key":"e_1_2_10_268_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2014.06.008"},{"key":"e_1_2_10_269_1","doi-asserted-by":"publisher","DOI":"10.1002\/mc.21863"},{"key":"e_1_2_10_270_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1600895"},{"key":"e_1_2_10_271_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)30054-X"},{"key":"e_1_2_10_272_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.cellbio.22.010305.104315"},{"key":"e_1_2_10_273_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2015.1546"},{"key":"e_1_2_10_274_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2492"},{"key":"e_1_2_10_275_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbalip.2013.02.010"},{"key":"e_1_2_10_276_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.25429"},{"key":"e_1_2_10_277_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.1964"},{"key":"e_1_2_10_278_1","first-page":"710","article-title":"In\u00a0vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue","volume":"118","author":"Nishimura S","year":"2008","journal-title":"J\u00a0Clin Invest"},{"key":"e_1_2_10_279_1","doi-asserted-by":"crossref","first-page":"345","DOI":"10.4049\/jimmunol.160.1.345","article-title":"Neutrophils but not eosinophils are involved in growth suppression of IL\u20104\u2010secreting tumors","volume":"160","author":"Noffz G","year":"1998","journal-title":"J\u00a0Immunol"},{"key":"e_1_2_10_280_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20131916"},{"key":"e_1_2_10_281_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6603962"},{"key":"e_1_2_10_282_1","article-title":"Obesity but not high\u2010fat diet impairs lymphatic function","author":"Nores GD","year":"2016","journal-title":"Int J Obes (Lond)"},{"key":"e_1_2_10_283_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0601807103"},{"issue":"2","key":"e_1_2_10_284_1","first-page":"11","article-title":"Obesity and prostate cancer","volume":"13","author":"O'Malley RL","year":"2006","journal-title":"Can J Urol"},{"key":"e_1_2_10_285_1","first-page":"213","article-title":"Role of adiponectin and its receptors in cancer","volume":"9","author":"Obeid S","year":"2012","journal-title":"Cancer Biol Med"},{"key":"e_1_2_10_286_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-06-2197"},{"key":"e_1_2_10_287_1","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-13-0214"},{"key":"e_1_2_10_288_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.6361"},{"key":"e_1_2_10_289_1","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2009.080676"},{"key":"e_1_2_10_290_1","first-page":"21","article-title":"Obesity\u2010driven inflammation and cancer risk: Role of myeloid derived suppressor cells and alternately activated macrophages","volume":"3","author":"Okwan\u2010Duodu D","year":"2013","journal-title":"Am J Cancer Res"},{"key":"e_1_2_10_291_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-007-6211-4_18"},{"key":"e_1_2_10_292_1","first-page":"8","article-title":"The mouse prostate: A basic anatomical and histological guideline","volume":"16","author":"Oliveira DSM","year":"2016","journal-title":"Bosn J Basic Med Sci"},{"key":"e_1_2_10_293_1","doi-asserted-by":"publisher","DOI":"10.2337\/db08-0536"},{"key":"e_1_2_10_294_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S93483"},{"key":"e_1_2_10_295_1","doi-asserted-by":"publisher","DOI":"10.4137\/CMO.S32812"},{"key":"e_1_2_10_296_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1071420"},{"key":"e_1_2_10_297_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.20383"},{"key":"e_1_2_10_298_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2014.94"},{"key":"e_1_2_10_299_1","doi-asserted-by":"publisher","DOI":"10.1002\/emmm.201202006"},{"key":"e_1_2_10_300_1","doi-asserted-by":"publisher","DOI":"10.1530\/ERC-11-0163"},{"key":"e_1_2_10_301_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI63930"},{"key":"e_1_2_10_302_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-0947"},{"key":"e_1_2_10_303_1","doi-asserted-by":"publisher","DOI":"10.1186\/2052-9538-1-9"},{"key":"e_1_2_10_304_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2014.06.011"},{"key":"e_1_2_10_305_1","doi-asserted-by":"publisher","DOI":"10.1513\/pats.200708-146DR"},{"key":"e_1_2_10_306_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2011.06.004"},{"key":"e_1_2_10_307_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-15-0927"},{"key":"e_1_2_10_308_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-012-2339-3"},{"key":"e_1_2_10_309_1","doi-asserted-by":"publisher","DOI":"10.1002\/stem.523"},{"key":"e_1_2_10_310_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2005.08.023"},{"key":"e_1_2_10_311_1","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.1107762"},{"key":"e_1_2_10_312_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2012.06.003"},{"key":"e_1_2_10_313_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1612920114"},{"key":"e_1_2_10_314_1","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2009.299"},{"key":"e_1_2_10_315_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature10138"},{"key":"e_1_2_10_316_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.03.014"},{"key":"e_1_2_10_317_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12935-016-0300-y"},{"key":"e_1_2_10_318_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3394"},{"key":"e_1_2_10_319_1","first-page":"957","article-title":"Interplay between mast cells and lymphatic vessels in different molecular types of breast cancer","volume":"33","author":"Raica M","year":"2013","journal-title":"Anticancer Res"},{"key":"e_1_2_10_320_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-007-9546-3"},{"key":"e_1_2_10_321_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2009-0283"},{"key":"e_1_2_10_322_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drup.2009.03.002"},{"key":"e_1_2_10_323_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-012-2185-3"},{"key":"e_1_2_10_324_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-01-0226"},{"key":"e_1_2_10_325_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-71518-6_14"},{"key":"e_1_2_10_326_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2613.2010.00726.x"},{"key":"e_1_2_10_327_1","doi-asserted-by":"publisher","DOI":"10.1186\/1756-9966-31-32"},{"key":"e_1_2_10_328_1","doi-asserted-by":"publisher","DOI":"10.1258\/ebm.2012.012131"},{"key":"e_1_2_10_329_1","doi-asserted-by":"publisher","DOI":"10.1159\/000337604"},{"key":"e_1_2_10_330_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2015.02.005"},{"key":"e_1_2_10_331_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20050715"},{"key":"e_1_2_10_332_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-04-0465"},{"key":"e_1_2_10_333_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4171"},{"key":"e_1_2_10_334_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.162349799"},{"key":"e_1_2_10_335_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3800651"},{"key":"e_1_2_10_336_1","doi-asserted-by":"publisher","DOI":"10.2174\/0929867323666160119094313"},{"key":"e_1_2_10_337_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.11340"},{"key":"e_1_2_10_338_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0038812"},{"key":"e_1_2_10_339_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2011.18"},{"key":"e_1_2_10_340_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-065X.2000.17706.x"},{"key":"e_1_2_10_341_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a003228"},{"key":"e_1_2_10_342_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.1942"},{"key":"e_1_2_10_343_1","unstructured":"SchneiderB.Randomized controlled trial of genomically girected therapy in patients with triple negative breast cancer. In:ClinicalTrials.govidentifier NCT02101385 2016."},{"key":"e_1_2_10_344_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.12.017"},{"key":"e_1_2_10_345_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3010467"},{"key":"e_1_2_10_346_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni1309"},{"key":"e_1_2_10_347_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.27.2021"},{"key":"e_1_2_10_348_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0033308"},{"key":"e_1_2_10_349_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1203785"},{"key":"e_1_2_10_350_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-0141"},{"key":"e_1_2_10_351_1","doi-asserted-by":"publisher","DOI":"10.2337\/db09-1402"},{"key":"e_1_2_10_352_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-04-0340"},{"key":"e_1_2_10_353_1","article-title":"Therapeutic lymphangiogenesis with implantation of adipose\u2010derived regenerative cells","volume":"1","author":"Shimizu Y","year":"2012","journal-title":"J\u00a0Am Heart Assoc"},{"key":"e_1_2_10_354_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2009.10.002"},{"key":"e_1_2_10_355_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI88606"},{"key":"e_1_2_10_356_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-10-0489"},{"key":"e_1_2_10_357_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.180331.111"},{"key":"e_1_2_10_358_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21254"},{"key":"e_1_2_10_359_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0802987"},{"key":"e_1_2_10_360_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-4174"},{"key":"e_1_2_10_361_1","doi-asserted-by":"publisher","DOI":"10.1038\/84643"},{"key":"e_1_2_10_362_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1212"},{"key":"e_1_2_10_363_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3892"},{"key":"e_1_2_10_364_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00329.2010"},{"key":"e_1_2_10_365_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830250535"},{"key":"e_1_2_10_366_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-2-2"},{"key":"e_1_2_10_367_1","doi-asserted-by":"publisher","DOI":"10.1002\/stem.1229"},{"key":"e_1_2_10_368_1","doi-asserted-by":"publisher","DOI":"10.1186\/bcr3569"},{"key":"e_1_2_10_369_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-16-0439"},{"key":"e_1_2_10_370_1","doi-asserted-by":"publisher","DOI":"10.1158\/1940-6207.CAPR-10-0381"},{"key":"e_1_2_10_371_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-11-0241"},{"key":"e_1_2_10_372_1","doi-asserted-by":"publisher","DOI":"10.1042\/BC20080221"},{"key":"e_1_2_10_373_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms4485"},{"key":"e_1_2_10_374_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2013.06.016"},{"key":"e_1_2_10_375_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-011-1789-3"},{"key":"e_1_2_10_376_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0111394"},{"key":"e_1_2_10_377_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-013-2741-5"},{"key":"e_1_2_10_378_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2014.00175"},{"key":"e_1_2_10_379_1","doi-asserted-by":"publisher","DOI":"10.1080\/00313020600820914"},{"key":"e_1_2_10_380_1","doi-asserted-by":"publisher","DOI":"10.1381\/0960892054222678"},{"key":"e_1_2_10_381_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3971"},{"key":"e_1_2_10_382_1","first-page":"247","article-title":"The relationship between inflammatory markers, angiogenesis, and obesity","volume":"9","author":"Tahergorabi Z","year":"2013","journal-title":"ARYA Atheroscler"},{"key":"e_1_2_10_383_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.192.2.303"},{"key":"e_1_2_10_384_1","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0000000000000084"},{"key":"e_1_2_10_385_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2885"},{"key":"e_1_2_10_386_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0004974"},{"key":"e_1_2_10_387_1","doi-asserted-by":"crossref","first-page":"4939","DOI":"10.18632\/oncotarget.6643","article-title":"Adipocytes promote prostate cancer stem cell self\u2010renewal through amplification of the cholecystokinin autocrine loop","volume":"7","author":"Tang KD","year":"2016","journal-title":"Oncotarget"},{"key":"e_1_2_10_388_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-2896.2005.00275.x"},{"key":"e_1_2_10_389_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2008.157669"},{"key":"e_1_2_10_390_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1636093"},{"key":"e_1_2_10_391_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2004.02.013"},{"key":"e_1_2_10_392_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri1937"},{"key":"e_1_2_10_393_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc927"},{"key":"e_1_2_10_394_1","doi-asserted-by":"publisher","DOI":"10.1152\/physiol.00019.2005"},{"key":"e_1_2_10_395_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOG.0b013e3283347e77"},{"key":"e_1_2_10_396_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coi.2011.12.009"},{"key":"e_1_2_10_397_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clgc.2013.07.013"},{"key":"e_1_2_10_398_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2014.195"},{"key":"e_1_2_10_399_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00017.2012"},{"key":"e_1_2_10_400_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000128860.00639.9c"},{"key":"e_1_2_10_401_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1205129109"},{"key":"e_1_2_10_402_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.25788"},{"key":"e_1_2_10_403_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.2006-0033"},{"key":"e_1_2_10_404_1","doi-asserted-by":"publisher","DOI":"10.1080\/23320885.2017.1316201"},{"key":"e_1_2_10_405_1","first-page":"225","article-title":"Coexpression of hepatocyte growth factor and receptor (Met) in human breast carcinoma","volume":"148","author":"Tuck AB","year":"1996","journal-title":"Am J Pathol"},{"key":"e_1_2_10_406_1","first-page":"335","article-title":"The prognostic impact of obesity on molecular subtypes of breast cancer in premenopausal women","volume":"18","author":"Turkoz FP","year":"2013","journal-title":"J\u00a0BUON"},{"key":"e_1_2_10_407_1","first-page":"2912","article-title":"Reactive stroma in human prostate cancer: Induction of myofibroblast phenotype and extracellular matrix remodeling","volume":"8","author":"Tuxhorn JA","year":"2002","journal-title":"Clin Cancer Res"},{"key":"e_1_2_10_408_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1260419"},{"key":"e_1_2_10_409_1","doi-asserted-by":"publisher","DOI":"10.1186\/bcr1260"},{"issue":"2","key":"e_1_2_10_410_1","first-page":"S94","article-title":"Weight control and physical activity in cancer prevention: International evaluation of the evidence","volume":"11","author":"Vainio H","year":"2002","journal-title":"Eur J Cancer Prev"},{"key":"e_1_2_10_411_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.09.024"},{"key":"e_1_2_10_412_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.2010.02414.x"},{"key":"e_1_2_10_413_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-09-0372"},{"key":"e_1_2_10_414_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2010.09811.x"},{"key":"e_1_2_10_415_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-009-0497-7"},{"key":"e_1_2_10_416_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V97.8.2478"},{"key":"e_1_2_10_417_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0940-9602(02)80016-4"},{"key":"e_1_2_10_418_1","doi-asserted-by":"publisher","DOI":"10.1002\/pros.22756"},{"key":"e_1_2_10_419_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2003.014480"},{"key":"e_1_2_10_420_1","first-page":"506","article-title":"Collagen\u2010receptor signaling in health and disease","volume":"11","author":"Vogel WF.","year":"2001","journal-title":"Eur J Dermatol"},{"key":"e_1_2_10_421_1","doi-asserted-by":"publisher","DOI":"10.4061\/2011\/523276"},{"key":"e_1_2_10_422_1","doi-asserted-by":"publisher","DOI":"10.1677\/ERC-06-0068"},{"key":"e_1_2_10_423_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10456-012-9276-y"},{"key":"e_1_2_10_424_1","doi-asserted-by":"publisher","DOI":"10.4161\/adip.23016"},{"key":"e_1_2_10_425_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2009.11.009"},{"key":"e_1_2_10_426_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0710441105"},{"key":"e_1_2_10_427_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.87489"},{"key":"e_1_2_10_428_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2012.05.019"},{"key":"e_1_2_10_429_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2011.11.050"},{"key":"e_1_2_10_430_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI200319246"},{"key":"e_1_2_10_431_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0070703"},{"key":"e_1_2_10_432_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI44562"},{"key":"e_1_2_10_433_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2006.05.001"},{"key":"e_1_2_10_434_1","doi-asserted-by":"publisher","DOI":"10.2337\/db09-0287"},{"key":"e_1_2_10_435_1","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgq088"},{"key":"e_1_2_10_436_1","doi-asserted-by":"publisher","DOI":"10.1007\/0-387-26283-0_5"},{"key":"e_1_2_10_437_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13058-015-0639-3"},{"key":"e_1_2_10_438_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.25464"},{"key":"e_1_2_10_439_1","doi-asserted-by":"publisher","DOI":"10.1038\/npjbcancer.2015.25"},{"key":"e_1_2_10_440_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.1343"},{"key":"e_1_2_10_441_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-0901"},{"key":"e_1_2_10_442_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.14.12689"},{"key":"e_1_2_10_443_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200305010"},{"key":"e_1_2_10_444_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keq045"},{"key":"e_1_2_10_445_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1201475"},{"key":"e_1_2_10_446_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.05.016"},{"key":"e_1_2_10_447_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1255354"},{"key":"e_1_2_10_448_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.237123"},{"key":"e_1_2_10_449_1","first-page":"615","article-title":"Mast cell tryptase promotes breast cancer migration and invasion","volume":"23","author":"Xiang M","year":"2010","journal-title":"Oncol Rep"},{"key":"e_1_2_10_450_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI200319451"},{"key":"e_1_2_10_451_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2013.11.001"},{"key":"e_1_2_10_452_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2014.01.006"},{"key":"e_1_2_10_453_1","doi-asserted-by":"publisher","DOI":"10.1186\/bcr2102"},{"key":"e_1_2_10_454_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djr225"},{"key":"e_1_2_10_455_1","doi-asserted-by":"publisher","DOI":"10.1309\/MX6KKA1UNJ1YG8VN"},{"key":"e_1_2_10_456_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1000021"},{"key":"e_1_2_10_457_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-03-213595"},{"key":"e_1_2_10_458_1","first-page":"1","article-title":"PD\u20101, PD\u2010L1 and PD\u2010L2 expression in mouse prostate cancer","volume":"4","author":"Yang S","year":"2016","journal-title":"Am J Clin Exp Urol"},{"key":"e_1_2_10_459_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc11-0255"},{"key":"e_1_2_10_460_1","doi-asserted-by":"publisher","DOI":"10.2217\/rme.15.24"},{"key":"e_1_2_10_461_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0803632"},{"key":"e_1_2_10_462_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2010.123"},{"key":"e_1_2_10_463_1","article-title":"CXCL1 mediates obesity\u2010associated adipose stromal cell trafficking and function in the tumour microenvironment","volume":"7","author":"Zhang T","year":"2016","journal-title":"Nat Commun"},{"key":"e_1_2_10_464_1","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2014.2841"},{"key":"e_1_2_10_465_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-12-0294"},{"key":"e_1_2_10_466_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2015.09.013"},{"key":"e_1_2_10_467_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri1806"},{"key":"e_1_2_10_468_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e02-02-0105"},{"key":"e_1_2_10_469_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0007067"}],"container-title":["Comprehensive Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcphy.c170008","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cphy.c170008","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cphy.c170008","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cphy.c170008","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T16:34:32Z","timestamp":1693326872000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cphy.c170008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,12]]},"ISBN":["9780470650714"],"references-count":468,"alternative-id":["10.1002\/cphy.c170008","10.1002\/cphy"],"URL":"https:\/\/doi.org\/10.1002\/cphy.c170008","archive":["Portico"],"relation":{},"subject":[],"published":{"date-parts":[[2017,12,12]]}}}