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High pressure was conducive to enhanced product yields by a factor of 2\u201312 at a given reaction time, high reaction rates (reaction times were decreased from 72\u201324\u2005h down to 4\u201324\u2005h) and high enantioselectivity. Elucidating the effects of solvents for maximizing reaction rates and yields has been carried out using the Perturbed\u2010Chain Polar Statistical Associating Fluid Theory (PCP\u2010SAFT), allowing for the first time a prediction of the kinetic profiles under high\u2010hydrostatic\u2010pressure conditions.<\/jats:p>","DOI":"10.1002\/cplu.202000364","type":"journal-article","created":{"date-parts":[[2020,6,4]],"date-time":"2020-06-04T05:20:05Z","timestamp":1591248005000},"page":"1292-1296","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["High\u2010Pressure\u2010Mediated Thiourea\u2010Organocatalyzed Asymmetric Michael Addition to (Hetero)aromatic Nitroolefins: Prediction of Reaction Parameters by PCP\u2010SAFT Modelling"],"prefix":"10.1002","volume":"85","author":[{"given":"Thomas","family":"Weinbender","sequence":"first","affiliation":[{"name":"Institute of Organic Chemistry University of Regensburg  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