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Their in\u2010vitro photodynamic anticancer activities against A549, MDA\u2010MB\u2010231, B16, HepG2, and Hela cell lines were also investigated. Among three compounds, phosphorus(V) complexexhibits the best photostability, highest fluorescence quantum yields (\u03a6<jats:sub>F<\/jats:sub>=0.138), and the highest singlet\u2010oxygen quantum yields (\u03a6<jats:sub>\u0394<\/jats:sub>=0.87). Also, the phosphorus(V) complex exhibits the best photodynamic antitumor activity against MDA\u2010MB\u2010231 cells with a low IC<jats:sub>50<\/jats:sub> (0.08\u2005\u03bcM) upon light irradiation at 625\u00b12\u2005nm, which is much lower than commercial PDT drug Temoporfin (0.1\u2005\u03bcM) at the same conditions. The cellular localization assay confirmed that the phosphorus(V) complexis mainly distributed in the cytoplasm and have a good ability to produce reactive oxygen species (ROS) under light illumination, which would further cause oxidative damage to tumor cells and finally result in the apoptosis. After PDT treatment, phosphorus(V) complex may cause tumor cell arrest at the G2\/M stage. The preliminary results showed phosphorus(V) corrole complex is a good candidate for photodynamic therapy (PDT) of tumors.<\/jats:p>","DOI":"10.1002\/cplu.202200188","type":"journal-article","created":{"date-parts":[[2022,7,4]],"date-time":"2022-07-04T12:53:16Z","timestamp":1656939196000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Photodynamic Antitumor Activity of 5,15\u2010Bis(perfluorophenyl)\u201010\u2010(4\u2010carboxyphenyl)corrole and its Gallium(III) and Phosphorus(V) Complexes"],"prefix":"10.1002","volume":"87","author":[{"given":"Jing\u2010He","family":"Cen","sequence":"first","affiliation":[{"name":"School of Chemistry and Chemical Engineering Guangdong Provincial Key Laboratory of Fuel Cell Technology South China University of Technology  Guangzhou 510641 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bei","family":"Wan","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering Guangdong Provincial Key Laboratory of Fuel Cell Technology South China University of Technology  Guangzhou 510641 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue","family":"Zhao","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering Guangdong Provincial Key Laboratory of Fuel Cell Technology South China University of Technology  Guangzhou 510641 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meng\u2010Yuan","family":"Li","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering Guangdong Provincial Key Laboratory of Fuel Cell Technology South China University of Technology  Guangzhou 510641 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu\u2010Hui","family":"Liao","sequence":"additional","affiliation":[{"name":"Molecular Diagnosis and Treatment Center for Infectious Diseases Dermatology Hospital Southern Medical University  Guangzhou 510091 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1793-952X","authenticated-orcid":false,"given":"Hai\u2010Yang","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering Guangdong Provincial Key Laboratory of Fuel Cell Technology South China University of Technology  Guangzhou 510641 P. R. 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