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Consequently, the cell responds to external stimuli, playing an essential role in various life activities, such as nerve excitation conduction, neurotransmitter release, muscle movement, and control of cell differentiation. Supramolecular artificial channels, which mimic native protein channels in structure and function, adopt unimolecular or self\u2010assembled structures, such as crown ethers, cyclodextrins, cucurbiturils, column arenes, cyclic peptide nanotubes, and metal\u2010organic artificial channels, in channel construction strategies. Owing to the various driving forces involved, artificial synthetic ion channels can be divided into artificial cation and anion channels in terms of ion selectivity. Cation selectivity usually originates from ion coordination, whereas anion selectivity is related to hydrogen bonding, ion pairing, and anion\u2010dipole interactions. Several studies have been conducted on artificial cation channels, and several reviews have summarized them in detail; however, the research on anions is still in the initial stages, and related reviews have rarely been reported. Hence, this article primarily focuses on the recent research on anion channels.<\/jats:p>","DOI":"10.1002\/cplu.202400466","type":"journal-article","created":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T09:44:52Z","timestamp":1725011092000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Recent Advances in Artificial Anion Channels and Their Selectivity"],"prefix":"10.1002","volume":"89","author":[{"given":"Bowen","family":"Ren","sequence":"first","affiliation":[{"name":"State Key Laboratory of Antiviral Drugs Pingyuan Laboratory NMPA Key Laboratory for Research and Evaluation of Innovative Drug School of Chemistry and Chemical Engineering Henan Normal University  Xinxiang 453007 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-6105-4455","authenticated-orcid":false,"given":"Yonghui","family":"Sun","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Antiviral Drugs Pingyuan Laboratory NMPA Key Laboratory for Research and Evaluation of Innovative Drug School of Chemistry and Chemical Engineering Henan Normal University  Xinxiang 453007 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4947-7953","authenticated-orcid":false,"given":"Pengyang","family":"Xin","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Antiviral Drugs Pingyuan Laboratory NMPA Key Laboratory for Research and Evaluation of Innovative Drug School of Chemistry and Chemical Engineering Henan Normal University  Xinxiang 453007 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,23]]},"reference":[{"key":"e_1_2_6_1_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)47032-9"},{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1385\/CBB:35:3:263"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.physiol.67.032003.154341"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/356057a0"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2008.02.013"},{"key":"e_1_2_6_6_1","unstructured":"\u00a0"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.38506"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature10870"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2005.06.053"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2019.04.020"},{"key":"e_1_2_6_11_1","unstructured":"\u00a0"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2021.678962"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201915287"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.3184\/003685002783238780"},{"key":"e_1_2_6_15_1","unstructured":"\u00a0"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/tcr.202100225"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1039\/D0PY01558J"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.202100112"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1039\/D1SC03545B"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1039\/C9CS00662A"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1039\/C7CS00159B"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201207535"},{"key":"e_1_2_6_23_1","unstructured":"\u00a0"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c07977"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c02881"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature04712"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja016784d"},{"key":"e_1_2_6_28_1","doi-asserted-by":"crossref","unstructured":"P.\u2005H. 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