{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T07:04:18Z","timestamp":1785135858819,"version":"3.55.0"},"reference-count":31,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T00:00:00Z","timestamp":1783209600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ChemPlusChem"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:p>\n                    The formation, structural diversity, and photoreactivity of members of a series of hydrogen\u2010bonded mixed cocrystals were achieved by changing the halogen atoms of trihalophenols; namely, 2,4,6\u2010trichlorophenol, 2,4,6\u2010tribromophenol, and 2,4,6\u2010triiodophenol. The inclusion of two isosteric hydrogen\u2010bond donors led to structural diversity and different photochemical behavior when combined with\n                    <jats:italic>trans<\/jats:italic>\n                    \u20101,2\u2010bis(4\u2010pyridyl)ethylene. The realization of a three\u2010component mixed cocrystal was achieved when combining neighboring halogen atoms such as Cl\/Br and Br\/I pairs. The mixed cocrystal based upon 2,4,6\u2010trichlorophenol and 2,4,6\u2010tribromophenol was the only mixed solid to undergo a [2\u2009+\u20092] photocycloaddition reaction. The overall yield for the equal molar\u2010mixed cocrystal lies at the midpoint between the two binary cocrystals, which demonstrates that the extent of a solid\u2010state photoreaction can be affected using halogen exchange. The mixed cocrystal containing 2,4,6\u2010tribromophenol and 2,4,6\u2010triiodophenol yielded a different face\u2010to\u2010face\n                    <jats:italic>\u03c0<\/jats:italic>\n                    \u2013\n                    <jats:italic>\u03c0<\/jats:italic>\n                    stacking pattern, which illustrates that the type of halogen atom can influence crystal packing. The mixed cocrystal was determined to be photostable owing to improper positioning of the carbon\u2500carbon double bond. To test structural reliability, an additional isostructural mixed cocrystal for each system was also realized by using 1,2\u2010bis(4\u2010pyridyl)acetylene as a hydrogen\u2010bond acceptor.\n                  <\/jats:p>","DOI":"10.1002\/cplu.70193","type":"journal-article","created":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T20:47:28Z","timestamp":1783284448000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Probing the Landscape of Photoactive Mixed Cocrystals: Unexpected Photostability Involving a Br\/I Halogen Exchange"],"prefix":"10.1002","volume":"91","author":[{"given":"Tyler L. H.","family":"Ramstack","sequence":"first","affiliation":[{"name":"Department of Natural Sciences and Mathematics Webster University  St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel K.","family":"Unruh","sequence":"additional","affiliation":[{"name":"Office of the Vice President for Research University of Iowa  Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0875-677X","authenticated-orcid":false,"given":"Leonard R.","family":"MacGillivray","sequence":"additional","affiliation":[{"name":"Department of Chemistry University of Sherbrooke  Sherbrooke Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4602-6287","authenticated-orcid":false,"given":"Ryan H.","family":"Groeneman","sequence":"additional","affiliation":[{"name":"Department of Natural Sciences and Mathematics Webster University  St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.cgd.7b01643"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1039\/C8CE00691A"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.cgd.8b00972"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b12501"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200604830"},{"key":"e_1_2_8_7_1","first-page":"240031","article-title":"Organic Cocrystal Alloys: From Three Primary Colors to Continuously Tunable Emission and Applications on Optical Waveguides and Displays","volume":"20","author":"Zhang J.\u2010X.","year":"2024","journal-title":"Small"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1021\/cg800454r"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3CE01106B"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1039\/c2cc15453f"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1039\/c9pp00004f"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1107\/S2053229625001913"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.cgd.1c01285"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1021\/cm800923r"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1039\/C3NJ01395B"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5CC03033A"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.cgd.3c00304"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1039\/D4NJ01769B"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.cgd.9b00035"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.200500983"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1351\/pac197127040647"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1107\/S2053273314026370"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1107\/S2053229614024218"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1107\/S0021889808042726"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12039-010-0056-1"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja001239i"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/ic100853h"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1039\/b813850h"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1021\/cg500962y"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1021\/ar5001555"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr00078a009"},{"key":"e_1_2_8_32_1","unstructured":"Deposition numbers for (C6H2Cl3OH)1.18\u00b7(C6H2Br3OH)0.82\u00b7(BPE) is 2495151 (C6H2Br3OH).80\u00b7(C6H2I3OH)1.20\u00b7(BPE) is 2495152 (C6H2Cl3OH)1.15\u00b7(C6H2Br3OH)0.85\u00b7(BPA) is 2535113 and (C6H2Br3OH)1.02\u00b7(C6H2I3OH)0.98\u00b7(BPA) is 2516927 contain the supplementary crystallographic data for this paper. These data are provided free of charge by the joint Cambridge Crystallographic Data Centre and Fachinformationszentrum Karlsruhe Access Structures service."}],"container-title":["ChemPlusChem"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cplu.70193","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cplu.70193","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cplu.70193","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T06:49:16Z","timestamp":1785134956000},"score":1,"resource":{"primary":{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/10.1002\/cplu.70193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":31,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1002\/cplu.70193"],"URL":"https:\/\/doi.org\/10.1002\/cplu.70193","archive":["Portico"],"relation":{},"ISSN":["2192-6506","2192-6506"],"issn-type":[{"value":"2192-6506","type":"print"},{"value":"2192-6506","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"2026-03-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70193"}}