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This review aimed to determine (a) the quality of therapeutic alliance between people with schizophrenia and their therapists; (b) whether alliance predicts therapeutic outcomes; and (c) variables associated with alliance. Databases were searched from inception up to April 2015. The search yielded 4,586 articles, resulting in 26 eligible studies, involving 18 independent samples. Weighted average client and therapist Working Alliance Inventory\u2010Short Form total scores were 64.51 and 61.26, respectively. There was evidence that alliance predicts overall psychotic symptomatic outcomes and preliminary evidence for alliance predicting rehospitalization, medication use, and self\u2010esteem outcomes. There was evidence for specific client\u2010related factors being linked to different perspectives of alliance. For example, poorer insight and previous sexual abuse were associated with worse client\u2010rated alliance, whereas baseline negative symptoms were associated with worse therapist\u2010rated alliance. Therapist and therapy\u2010related factors, including therapists' genuineness, trustworthiness, and empathy were associated with better client\u2010rated alliance, whereas suitability for therapy, homework compliance, and attendance were associated with better therapist\u2010rated alliance. Key clinical implications include the need to consider alliance from both client and therapist perspectives during therapy and training and supervision to enhance therapist qualities that foster good alliance. Future research requires longitudinal studies with larger samples that include pan\u2010theoretical, well\u2010validated alliance measures to determine causal predictor variables.<\/jats:p>","DOI":"10.1002\/cpp.2135","type":"journal-article","created":{"date-parts":[[2017,9,29]],"date-time":"2017-09-29T13:00:28Z","timestamp":1506690028000},"source":"Crossref","is-referenced-by-count":123,"title":["Therapeutic alliance in psychological therapy for people with schizophrenia and related psychoses: A systematic review"],"prefix":"10.1002","volume":"25","author":[{"given":"Lucy","family":"Shattock","sequence":"first","affiliation":[{"name":"Division of Psychology and Mental Health, School of Health Sciences University of Manchester  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7399-5462","authenticated-orcid":false,"given":"Katherine","family":"Berry","sequence":"additional","affiliation":[{"name":"Division of Psychology and Mental Health, School of Health Sciences University of Manchester  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Degnan","sequence":"additional","affiliation":[{"name":"Division of Psychology and Mental Health, School of Health Sciences University of Manchester  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawn","family":"Edge","sequence":"additional","affiliation":[{"name":"Division of Psychology and Mental Health, School of Health Sciences University of Manchester  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,9,29]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-7358(02)00146-0"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/00332747.1988.11024404"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2753.2010.01516.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1037\/ccp0000015"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/NMD.0b013e3181da4d4e"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2015.04.006"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1037\/h0085885"},{"issue":"1","key":"e_1_2_6_9_1","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.psychres.2010.10.018","article-title":"Therapeutic relationships in vocational rehabilitation: Predicting good relationships for people with psychosis","volume":"187","author":"Catty J.","year":"2011","journal-title":"Psychiatry Research"},{"issue":"4","key":"e_1_2_6_10_1","first-page":"17","article-title":"Factors influencing the evaluation of the relationship between schizophrenic patients and their therapists in two different therapeutic context","volume":"2","author":"Cechnicki A.","year":"2000","journal-title":"Archives of Psychiatry and Psychotherapy"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0005-7967(02)00033-5"},{"key":"e_1_2_6_12_1","first-page":"1","article-title":"Therapists' recognition of alliance ruptures as a moderator of change in alliance and symptoms","author":"Chen R.","year":"2016","journal-title":"Psychotherapy Research"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.72.3.411"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.nmd.0000195315.39196.52"},{"issue":"3","key":"e_1_2_6_15_1","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1891\/152109807781753745","article-title":"Client outcomes and the working alliance in the client\u2013case manager relationship: A causal analysis","volume":"8","author":"Cunningham J.","year":"2007","journal-title":"Care Management Journals"},{"issue":"8","key":"e_1_2_6_16_1","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1016\/j.cpr.2006.02.001","article-title":"Adult attachment patterns and individual psychotherapy: A review","volume":"26","author":"Daniels S. 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