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Few studies, however, have assessed parental bonding during childhood as a predictor of response to anxiety disorders treatment. The aim of the study was to examine whether emotional memories of childhood parenting could predict short\u2010term and long\u2010term outcome in three different interventions for patients with generalized anxiety disorder (GAD): mindfulness\u2010based intervention (Body in Mind Training [BMT]), fluoxetine (FLX), and an active control group (quality of life [QoL]). A total of 124 participants from a randomized controlled trial for GAD treatment were evaluated pre\u2010 and post\u2010treatment and after 18\u2009months. Patients were assessed for the severity of GAD symptoms (GAD\u20107, PSWQ, and DERS), early memories of warmth and safeness (EMWSS), and recall of perceived threat and subordination\/submission in childhood (ELES). Negative childhood memories predicted a greater reduction in anxiety symptoms on BMT treatment compared to FLX and QoL, whereas positive childhood memories predicted more symptomatic improvement in the QoL group. Our findings suggest that individuals with GAD who have early memories of subordination and threat appear to benefit more from interventions that focus on developing emotion\u2010regulation strategies and enhancing self\u2010compassion, such as mindfulness\u2010based interventions.<\/jats:p>","DOI":"10.1002\/cpp.2804","type":"journal-article","created":{"date-parts":[[2022,11,22]],"date-time":"2022-11-22T18:19:27Z","timestamp":1669141167000},"page":"387-397","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Early emotional memories and bonding as predictors of short\u2010term and long\u2010term outcome in adults with generalized anxiety disorder"],"prefix":"10.1002","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5466-8167","authenticated-orcid":false,"given":"Vivian Pinto","family":"Vaz","sequence":"first","affiliation":[{"name":"Graduate Program in Psychiatry and Behavioral Sciences, School of Medicine Universidade Federal do Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marianna de Abreu","family":"Costa","sequence":"additional","affiliation":[{"name":"Graduate Program in Psychiatry and Behavioral Sciences, School of Medicine Universidade Federal do Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fl\u00e1via","family":"de Moraes","sequence":"additional","affiliation":[{"name":"Graduate Program in Psychiatry and Behavioral Sciences, School of Medicine Universidade Federal do Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guilherme Abu Hilu","family":"Garcia","sequence":"additional","affiliation":[{"name":"Graduate Program in Psychiatry and Behavioral Sciences, School of Medicine Universidade Federal do Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gisele Gus","family":"Manfro","sequence":"additional","affiliation":[{"name":"Graduate Program in Psychiatry and Behavioral Sciences, School of Medicine Universidade Federal do Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,12,8]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2017.06.050"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0706743718779933"},{"issue":"10","key":"e_1_2_12_4_1","first-page":"24","article-title":"Effect of mindfulness based stress management on reduction of generalized anxiety disorder","volume":"41","author":"Asmaee Majid S.","year":"2012","journal-title":"Iranian Journal of Public Health"},{"issue":"22","key":"e_1_2_12_5_1","first-page":"29","article-title":"Clinical guidelines for establishing remission in patients with depression and anxiety","volume":"60","author":"Ballenger J. 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