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These programmes have as their basic idea that disorders are not separate entities but share common aetiological and maintenance processes. Their use is important with children, who tend to present less differentiated psychopathological manifestations than adults. This systematic review aimed to examine the effectiveness of four evidence\u2010based transdiagnostic programmes: FRIENDS, Pyramid Club, Unified Protocol for Children (UP\u2010C) and Super Skills for Life (SSL). Studies from 2018 to 2023 including children between 4 and 14\u2009years of age were examined. Following PRISMA guidelines, 48 studies that met the inclusion criteria were considered. Most of the studies referred to treatment, only a few used the selected transdiagnostic programmes for prevention, most notably FRIENDS and SSL. Very few of the studies reviewed have been randomized controlled trials, limiting the possibility to examine incremental benefits of these programmes over alternative approaches. The findings show that all programmes showed evidence of effectiveness, but UP\u2010C and SSL appear to be the most promising transdiagnostic programmes for the prevention and treatment of anxiety and depression in children as supported by more numerous studies in recent years. Moreover, UP\u2010C and SSL specifically appeared effective in reducing externalizing problems and improving social skills and prosocial behaviour. Although the results presented are promising, they should be regarded as provisional and in need of further support in randomized controlled trials to test the effectiveness of these evidence\u2010based programmes to ensure the psychological well\u2010being of children and thus reduce healthcare costs.<\/jats:p>","DOI":"10.1002\/cpp.70072","type":"journal-article","created":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T00:59:03Z","timestamp":1746579543000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A Systematic Review Comparing Four Transdiagnostic Programmes for School\u2010Age Children"],"prefix":"10.1002","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-9844-3575","authenticated-orcid":false,"given":"Giorgio","family":"Ghizzoni","sequence":"first","affiliation":[{"name":"Department of Philosophy, Social Sciences and Education University of Perugia  Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7395-1534","authenticated-orcid":false,"given":"Maria","family":"Mirandi","sequence":"additional","affiliation":[{"name":"Department of Philosophy, Social Sciences and Education University of Perugia  Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2306-6961","authenticated-orcid":false,"given":"Carlo","family":"Garofalo","sequence":"additional","affiliation":[{"name":"Department of Philosophy, Social Sciences and Education University of Perugia  Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6861-2009","authenticated-orcid":false,"given":"Claudia","family":"Mazzeschi","sequence":"additional","affiliation":[{"name":"Department of Philosophy, Social Sciences and Education University of Perugia  Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3519-5445","authenticated-orcid":false,"given":"Elisa","family":"Delvecchio","sequence":"additional","affiliation":[{"name":"Department of Philosophy, Social Sciences and Education University of Perugia  Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,6]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"Parenting Stress Index: Professional Manual","author":"Abidin R. 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