{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T16:18:41Z","timestamp":1792513121091,"version":"4.5.0"},"reference-count":48,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,8,9]],"date-time":"2018-08-09T00:00:00Z","timestamp":1533772800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001868","name":"National Science Council","doi-asserted-by":"publisher","award":["MOST103\u20102321\u2010B\u2010182\u2010001"],"award-info":[{"award-number":["MOST103\u20102321\u2010B\u2010182\u2010001"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001868","name":"National Science Council","doi-asserted-by":"publisher","award":["MOST101\u20102628\u2010B\u2010182\u2010001\u2010MY3"],"award-info":[{"award-number":["MOST101\u20102628\u2010B\u2010182\u2010001\u2010MY3"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001868","name":"National Science Council","doi-asserted-by":"publisher","award":["MOST104\u20102314\u2010B\u2010182A\u2010148\u2010MY3"],"award-info":[{"award-number":["MOST104\u20102314\u2010B\u2010182A\u2010148\u2010MY3"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001868","name":"National Science Council","doi-asserted-by":"publisher","award":["MOST104\u20102325\u2010B\u2010182A\u2010006"],"award-info":[{"award-number":["MOST104\u20102325\u2010B\u2010182A\u2010006"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["CLRPG2E0051\u223c3"],"award-info":[{"award-number":["CLRPG2E0051\u223c3"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["CORPG3F0041\u223c2"],"award-info":[{"award-number":["CORPG3F0041\u223c2"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["OMRPG3E0041"],"award-info":[{"award-number":["OMRPG3E0041"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["CMRPG1F0111\u223c2"],"award-info":[{"award-number":["CMRPG1F0111\u223c2"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004192","name":"National Science and Technology Development Agency","doi-asserted-by":"publisher","award":["P\u201013\u201000555"],"award-info":[{"award-number":["P\u201013\u201000555"]}],"id":[{"id":"10.13039\/501100004192","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ascpt.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Pharma and Therapeutics"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p>Specific ethnic genetic backgrounds are associated with the risk of Stevens\u2013Johnson syndrome \/ toxic epidermal necrolysis (SJS\/TEN) especially in Asians. However, there have been no large cohort, multiple\u2010country epidemiological studies of medication risk related to SJS\/TEN in Asian populations. Thus, we analyzed the registration databases from multiple Asian countries who were treated during 1998\u20132017. A total 1,028 SJS\/TEN cases were identified with the algorithm of drug causality for epidermal necrolysis. Furthermore, those medications labeled by the US Food and Drug Administration (FDA) as carrying a risk of SJS\/TEN were also compared with the common causes of SJS\/TEN in Asian countries. Oxcarbazepine, sulfasalazine, COX\u2010II inhibitors, and strontium ranelate were identified as new potential causes. In addition to sulfa drugs and beta\u2010lactam antibiotics, quinolones were also a common cause. Only one acetaminophen\u2010induced SJS was identified, while several medications (e.g., oseltamivir, terbinafine, isotretinoin, and sorafenib) labeled as carrying a risk of SJS\/TEN by the FDA were not found to have caused any of the cases in the Asian countries investigated in this study.<\/jats:p>","DOI":"10.1002\/cpt.1071","type":"journal-article","created":{"date-parts":[[2018,3,23]],"date-time":"2018-03-23T11:19:28Z","timestamp":1521803968000},"page":"112-120","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":71,"title":["The Medication Risk of Stevens\u2013Johnson Syndrome and Toxic Epidermal Necrolysis in Asians: The Major Drug Causality and Comparison With the US FDA Label"],"prefix":"10.1111","volume":"105","author":[{"given":"Yu\u2010Hsin","family":"Wang","sequence":"first","affiliation":[{"name":"Chang Gung Memorial Hospital Linkou Taiwan"},{"name":"Department of Dermatology Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital Taipei Linkou, and Keelung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun\u2010Bing","family":"Chen","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital Linkou Taiwan"},{"name":"Department of Dermatology Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital Taipei Linkou, and Keelung Taiwan"},{"name":"College of Medicine, Chang Gung University Taoyuan Taiwan"},{"name":"Graduate Institute of Clinical Medical Sciences, College of Medicine Chang Gung University Taoyuan Taiwan"},{"name":"Whole\u2010Genome Research Core Laboratory of Human Diseases, Chang Gung Memorial Hospital Keelung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wichittra","family":"Tassaneeyakul","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Faculty of Medicine Khon Kaen University Khon Kaen Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiro","family":"Saito","sequence":"additional","affiliation":[{"name":"Division of Medicinal Safety Science, National Institute of Health Sciences  Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michiko","family":"Aihara","sequence":"additional","affiliation":[{"name":"Department of Environmental Immuno\u2010Dermatology Yokohama City University Graduate School of Medicine Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siew Eng","family":"Choon","sequence":"additional","affiliation":[{"name":"Hospital Sultanah Aminah Johor Bahru, Clinical School of Medicine and Health Sciences Monash University Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haur Yueh","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Singapore General Hospital  Singapore"},{"name":"Duke\u2010NUS medical school  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mimi Mee","family":"Chang","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine and Therapeutics, Prince of Wales Hospital the Chinese University of Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisca D.","family":"Roa","sequence":"additional","affiliation":[{"name":"University of the Philippines\u2010Philippine, General Hospital Manila Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng\u2010Wei","family":"Wu","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Dermatology the First Affiliated Hospital of Fujian Medical University Fuzhou Fujian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nontaya","family":"Nakkam","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Faculty of Medicine Khon Kaen University Khon Kaen Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parinya","family":"Konyoung","sequence":"additional","affiliation":[{"name":"Pharmacy Unit, Udon Thani Hospital Udon Thani Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshimi","family":"Okamoto\u2010Uchida","sequence":"additional","affiliation":[{"name":"Division of Medicinal Safety Science, National Institute of Health Sciences  Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina Man\u2010tung","family":"Cheung","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine and Therapeutics, Prince of Wales Hospital the Chinese University of Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin\u2010wen","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Dermatology the First Affiliated Hospital of Fujian Medical University Fuzhou Fujian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Dermatology the First Affiliated Hospital of Fujian Medical University Fuzhou Fujian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Dermatology the First Affiliated Hospital of Fujian Medical University Fuzhou Fujian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosaline Chung\u2010Yee","family":"Hui","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital Linkou Taiwan"},{"name":"Department of Dermatology Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital Taipei Linkou, and Keelung Taiwan"},{"name":"College of Medicine, Chang Gung University Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia\u2010Yu","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Dermatology National Taiwan University Hospital and National Taiwan University College of Medicine Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi\u2010Ju","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Dermatology Taichung Veterans General Hospital, National Yang Ming University Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching\u2010Ying","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of dermatology municipal Ta\u2010Tong hospital, Kaohsiung medical university  Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao\u2010Kai","family":"Hsu","sequence":"additional","affiliation":[{"name":"Department of Dermatology National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsu\u2010Man","family":"Chiu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Changhua Christian Hospital Changhua Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Huei","family":"Huang","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital Linkou Taiwan"},{"name":"Department of Dermatology Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital Taipei Linkou, and Keelung Taiwan"},{"name":"College of Medicine, Chang Gung University Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun\u2010Wei","family":"Lu","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital Linkou Taiwan"},{"name":"Department of Dermatology Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital Taipei Linkou, and Keelung Taiwan"},{"name":"College of Medicine, Chang Gung University Taoyuan Taiwan"},{"name":"Graduate Institute of Clinical Medical Sciences, College of Medicine Chang Gung University Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chin\u2010Yi","family":"Yang","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital Linkou Taiwan"},{"name":"Department of Dermatology Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital Taipei Linkou, and Keelung Taiwan"},{"name":"College of Medicine, Chang Gung University Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi\u2010Ting","family":"Lin","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital Linkou Taiwan"},{"name":"Department of Dermatology Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital Taipei Linkou, and Keelung Taiwan"},{"name":"College of Medicine, Chang Gung University Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min\u2010Hui","family":"Chi","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital Linkou Taiwan"},{"name":"Department of Dermatology Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital Taipei Linkou, and Keelung Taiwan"},{"name":"College of Medicine, Chang Gung University Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsin\u2010Chun","family":"Ho","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital Linkou Taiwan"},{"name":"Department of Dermatology Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital Taipei Linkou, and Keelung Taiwan"},{"name":"College of Medicine, Chang Gung University Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing\u2010Yi","family":"Lin","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital Linkou Taiwan"},{"name":"Department of Dermatology Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital Taipei Linkou, and Keelung Taiwan"},{"name":"College of Medicine, Chang Gung University Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih\u2010Hsun","family":"Yang","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital Linkou Taiwan"},{"name":"Department of Dermatology Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital Taipei Linkou, and Keelung Taiwan"},{"name":"College of Medicine, Chang Gung University Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya\u2010Ching","family":"Chang","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital Linkou Taiwan"},{"name":"Department of Dermatology Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital Taipei Linkou, and Keelung Taiwan"},{"name":"College of Medicine, Chang Gung University Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih\u2010Chi","family":"Su","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital Linkou Taiwan"},{"name":"Department of Dermatology Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital Taipei Linkou, and Keelung Taiwan"},{"name":"Whole\u2010Genome Research Core Laboratory of Human Diseases, Chang Gung Memorial Hospital Keelung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuang Wei","family":"Wang","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital Linkou Taiwan"},{"name":"Department of Dermatology Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital Taipei Linkou, and Keelung Taiwan"},{"name":"Whole\u2010Genome Research Core Laboratory of Human Diseases, Chang Gung Memorial Hospital Keelung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen\u2010Lang","family":"Fan","sequence":"additional","affiliation":[{"name":"Whole\u2010Genome Research Core Laboratory of Human Diseases, Chang Gung Memorial Hospital Keelung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuen\u2010Iu","family":"Hung","sequence":"additional","affiliation":[{"name":"Institute of Pharmacology, School of Medicine, National Yang-Ming University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen\u2010Hung","family":"Chung","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital Linkou Taiwan"},{"name":"Department of Dermatology Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital Taipei Linkou, and Keelung Taiwan"},{"name":"College of Medicine, Chang Gung University Taoyuan Taiwan"},{"name":"Graduate Institute of Clinical Medical Sciences, College of Medicine Chang Gung University Taoyuan Taiwan"},{"name":"Whole\u2010Genome Research Core Laboratory of Human Diseases, Chang Gung Memorial Hospital Keelung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the Asian Severe Cutaneous Adverse Reaction Consortium","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,8,9]]},"reference":[{"key":"e_1_2_9_1_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2013.4114"},{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/428486a"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.5415\/apallergy.2015.5.2.68"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2010.04745.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0409500102"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/FPC.0b013e32834282b8"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/FPC.0b013e3282f3ef9c"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.2217\/pgs.15.128"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.2217\/14622416.7.6.813"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1013297"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2009.252"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.2217\/14622416.9.10.1543"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-5-39"},{"key":"e_1_2_9_14_1","unstructured":"U.S.F.D.A.Carbamazepine Prescribing Information to Include Recommendation of Genetic Test for Patients with Asian Ancestry\u2010Connection of genetic information with medication use can improve safe use of product. <http:\/\/www.fda.gov\/NewsEvents\/Newsroom\/PressAnnouncements\/2007\/ucm109038.htm> (2007)."},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/tpj.2013.40"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1009717"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000001034"},{"key":"e_1_2_9_18_1","unstructured":"Recommendations for HLA\u2010B*1502 genotype testing prior to initiation of carbamazepine in new patients. <http:\/\/www.hsa.gov.sg\/content\/hsa\/en\/Health_Products_Regulation\/Safety_Information_and_Product_Recalls\/Product_Safety_Alerts\/2013\/recommendations_for.html> (2013)."},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11096-013-9777-9"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2010.02549.x"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1009717"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000156354.20227.F0"},{"key":"e_1_2_9_23_1","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/BF00609428","article-title":"First dose and steady\u2010state pharmacokinetics of oxcarbazepine and its 10\u2010hydroxy metabolite","volume":"37","author":"Dickinson R.G.","year":"1989","journal-title":"Eur. J. Clin. Pharmacol."},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000003453"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2015.03.018"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/FPC.0000000000000153"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5701033"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2017.01.031"},{"key":"e_1_2_9_29_1","first-page":"Fc17","article-title":"Nevirapine: Most common cause of cutaneous adverse drug reactions in an outpatient department of a tertiary care hospital","volume":"9","author":"Pawar M.P.","year":"2015","journal-title":"J. Clin. Diagn. Res."},{"key":"e_1_2_9_30_1","unstructured":"U.S.F.D.A.Viramune (nevirapine) Dear Healthcare Professional Letter Nov 2000. <http:\/\/www.fda.gov\/safety\/medwatch\/safetyinformation\/safetyalertsforhumanmedicalproducts\/ucm175766.htm> (2000)."},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1097\/FPC.0000000000000124"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2011.0107"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit021"},{"key":"e_1_2_9_34_1","unstructured":"Services D.o.H.a.H.Guidelines for the Use of Antiretroviral Agents in HIV\u20101\u2010Infected Adults and Adolescents. (2016)."},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.alit.2016.04.001"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-014-2688-3"},{"key":"e_1_2_9_37_1","doi-asserted-by":"crossref","first-page":"510","DOI":"10.47102\/annals-acadmedsg.V40N11p510","article-title":"Stevens\u2010Johnson syndrome due to strontium ranelate","volume":"40","author":"Tan K.W.","year":"2011","journal-title":"Ann. Acad. Med. Singapore"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-013-2265-1"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-200528100-00008"},{"key":"e_1_2_9_40_1","unstructured":"World Health Organization.Mortality and prevalence data by WHO region (2007\u2013present). <http:\/\/apps.who.int\/gho\/data\/view.main.57016?lang=en> (2013)."},{"key":"e_1_2_9_41_1","unstructured":"World Health Organization.Tuberculosis. <http:\/\/www.who.int\/mediacentre\/factsheets\/fs104\/en\/> (2015)."},{"key":"e_1_2_9_42_1","article-title":"Delayed\u2010type hypersensitivity reactions induced by proton pump inhibitors: A clinical and in vitro T\u2010cell reactivity study","author":"Lin C.Y.","year":"2017","journal-title":"Allergy"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40264-014-0165-8"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40264-015-0390-9"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1993.01680220104023"},{"key":"e_1_2_9_46_1","first-page":"203","article-title":"Severe cutaneous adverse reactions to drugs (SCAR): Definitions, diagnostic criteria, genetic predisposition","volume":"27","author":"Roujeau J.\u2010C.","year":"2009","journal-title":"Dermatol. Sinica"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1981.154"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1021\/tx5005248"}],"container-title":["Clinical Pharmacology &amp; Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcpt.1071","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cpt.1071","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cpt.1071","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ascpt.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cpt.1071","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T13:35:17Z","timestamp":1699364117000},"score":1,"resource":{"primary":{"URL":"https:\/\/ascpt.onlinelibrary.wiley.com\/doi\/10.1002\/cpt.1071"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,9]]},"references-count":48,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.1002\/cpt.1071"],"URL":"https:\/\/doi.org\/10.1002\/cpt.1071","archive":["Portico"],"relation":{},"ISSN":["0009-9236","1532-6535"],"issn-type":[{"value":"0009-9236","type":"print"},{"value":"1532-6535","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,9]]},"assertion":[{"value":"2017-11-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-02-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}